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Iron in PDB 8uoq: Composite Map of PIC_DELTA_TFIIK FORM2

Enzymatic activity of Composite Map of PIC_DELTA_TFIIK FORM2

All present enzymatic activity of Composite Map of PIC_DELTA_TFIIK FORM2:
2.7.7.6; 3.6.4.12; 5.6.2.3;

Other elements in 8uoq:

The structure of Composite Map of PIC_DELTA_TFIIK FORM2 also contains other interesting chemical elements:

Zinc (Zn) 15 atoms
Magnesium (Mg) 2 atoms

Iron Binding Sites:

The binding sites of Iron atom in the Composite Map of PIC_DELTA_TFIIK FORM2 (pdb code 8uoq). This binding sites where shown within 5.0 Angstroms radius around Iron atom.
In total 4 binding sites of Iron where determined in the Composite Map of PIC_DELTA_TFIIK FORM2, PDB code: 8uoq:
Jump to Iron binding site number: 1; 2; 3; 4;

Iron binding site 1 out of 4 in 8uoq

Go back to Iron Binding Sites List in 8uoq
Iron binding site 1 out of 4 in the Composite Map of PIC_DELTA_TFIIK FORM2


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 1 of Composite Map of PIC_DELTA_TFIIK FORM2 within 5.0Å range:
probe atom residue distance (Å) B Occ
0:Fe801

b:287.9
occ:1.00
 FE1 0:SF4801 0.0 287.9 1.0
SG 0:CYS115 2.3 218.2 1.0
S4 0:SF4801 2.3 287.9 1.0
S3 0:SF4801 2.3 287.9 1.0
S2 0:SF4801 2.3 287.9 1.0
FE4 0:SF4801 2.7 287.9 1.0
FE2 0:SF4801 2.7 287.9 1.0
FE3 0:SF4801 2.7 287.9 1.0
CB 0:CYS115 2.9 218.2 1.0
CA 0:CYS115 3.2 218.2 1.0
C 0:CYS115 3.8 218.2 1.0
CB 0:HIS117 3.8 161.7 1.0
N 0:HIS117 3.8 161.7 1.0
S1 0:SF4801 3.9 287.9 1.0
N 0:LEU116 3.9 173.1 1.0
SG 0:CYS133 4.3 227.9 1.0
CA 0:HIS117 4.4 161.7 1.0
N 0:CYS115 4.5 218.2 1.0
CB 0:VAL120 4.6 197.9 1.0
O 0:CYS115 4.6 218.2 1.0
SG 0:CYS156 4.7 194.5 1.0
CB 0:CYS133 4.8 227.9 1.0
CG1 0:VAL120 4.8 197.9 1.0
O 0:HIS117 4.8 161.7 1.0
C 0:LEU116 4.8 173.1 1.0
SG 0:CYS191 4.9 199.4 1.0
CA 0:LEU116 5.0 173.1 1.0

Iron binding site 2 out of 4 in 8uoq

Go back to Iron Binding Sites List in 8uoq
Iron binding site 2 out of 4 in the Composite Map of PIC_DELTA_TFIIK FORM2


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 2 of Composite Map of PIC_DELTA_TFIIK FORM2 within 5.0Å range:
probe atom residue distance (Å) B Occ
0:Fe801

b:287.9
occ:1.00
 FE2 0:SF4801 0.0 287.9 1.0
SG 0:CYS156 2.3 194.5 1.0
S1 0:SF4801 2.3 287.9 1.0
S3 0:SF4801 2.3 287.9 1.0
S4 0:SF4801 2.3 287.9 1.0
FE1 0:SF4801 2.7 287.9 1.0
FE4 0:SF4801 2.7 287.9 1.0
FE3 0:SF4801 2.7 287.9 1.0
CB 0:CYS156 3.0 194.5 1.0
CB 0:HIS117 3.7 161.7 1.0
S2 0:SF4801 3.9 287.9 1.0
CG2 0:THR137 4.2 220.8 1.0
N 0:HIS117 4.3 161.7 1.0
SG 0:CYS191 4.4 199.4 1.0
N 0:HIS159 4.5 226.7 1.0
CG 0:HIS117 4.5 161.7 1.0
CA 0:CYS156 4.5 194.5 1.0
CB 0:HIS159 4.5 226.7 1.0
CA 0:HIS117 4.6 161.7 1.0
CB 0:TYR158 4.6 171.7 1.0
CB 0:CYS191 4.6 199.4 1.0
SG 0:CYS115 4.7 218.2 1.0
CD2 0:HIS117 4.7 161.7 1.0
SG 0:CYS133 5.0 227.9 1.0
CA 0:HIS159 5.0 226.7 1.0

Iron binding site 3 out of 4 in 8uoq

Go back to Iron Binding Sites List in 8uoq
Iron binding site 3 out of 4 in the Composite Map of PIC_DELTA_TFIIK FORM2


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 3 of Composite Map of PIC_DELTA_TFIIK FORM2 within 5.0Å range:
probe atom residue distance (Å) B Occ
0:Fe801

b:287.9
occ:1.00
 FE3 0:SF4801 0.0 287.9 1.0
S2 0:SF4801 2.3 287.9 1.0
S4 0:SF4801 2.3 287.9 1.0
S1 0:SF4801 2.3 287.9 1.0
SG 0:CYS133 2.3 227.9 1.0
FE1 0:SF4801 2.7 287.9 1.0
FE4 0:SF4801 2.7 287.9 1.0
FE2 0:SF4801 2.7 287.9 1.0
CB 0:CYS133 3.5 227.9 1.0
CG2 0:THR137 3.7 220.8 1.0
OG1 0:THR137 3.8 220.8 1.0
S3 0:SF4801 3.9 287.9 1.0
CE2 0:PHE194 4.1 239.5 1.0
CA 0:CYS133 4.3 227.9 1.0
CB 0:THR137 4.3 220.8 1.0
SG 0:CYS191 4.5 199.4 1.0
O 0:CYS133 4.6 227.9 1.0
CD2 0:PHE194 4.7 239.5 1.0
SG 0:CYS115 4.8 218.2 1.0
C 0:CYS133 4.8 227.9 1.0
SG 0:CYS156 4.9 194.5 1.0
CD2 0:TYR193 4.9 229.8 1.0
CB 0:CYS156 5.0 194.5 1.0

Iron binding site 4 out of 4 in 8uoq

Go back to Iron Binding Sites List in 8uoq
Iron binding site 4 out of 4 in the Composite Map of PIC_DELTA_TFIIK FORM2


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 4 of Composite Map of PIC_DELTA_TFIIK FORM2 within 5.0Å range:
probe atom residue distance (Å) B Occ
0:Fe801

b:287.9
occ:1.00
 FE4 0:SF4801 0.0 287.9 1.0
SG 0:CYS191 2.2 199.4 1.0
S1 0:SF4801 2.3 287.9 1.0
S3 0:SF4801 2.3 287.9 1.0
S2 0:SF4801 2.3 287.9 1.0
FE1 0:SF4801 2.7 287.9 1.0
FE2 0:SF4801 2.7 287.9 1.0
FE3 0:SF4801 2.7 287.9 1.0
CB 0:CYS191 3.4 199.4 1.0
S4 0:SF4801 3.9 287.9 1.0
CA 0:CYS115 4.2 218.2 1.0
CA 0:CYS191 4.3 199.4 1.0
CB 0:TYR193 4.3 229.8 1.0
N 0:LEU116 4.3 173.1 1.0
O 0:LEU114 4.4 240.4 1.0
CD2 0:PHE194 4.4 239.5 1.0
CD2 0:TYR193 4.6 229.8 1.0
SG 0:CYS156 4.7 194.5 1.0
SG 0:CYS133 4.7 227.9 1.0
CB 0:CYS115 4.7 218.2 1.0
CE2 0:PHE194 4.7 239.5 1.0
SG 0:CYS115 4.8 218.2 1.0
C 0:CYS115 4.8 218.2 1.0
C 0:CYS191 4.9 199.4 1.0
CG 0:TYR193 4.9 229.8 1.0

Reference:

C.Yang, P.Basnet, S.Sharmin, H.Shen, C.D.Kaplan, K.Murakami. Transcription Start Site Scanning Requires the Fungi-Specific Hydrophobic Loop of TFB3. Nucleic Acids Res. 2024.
ISSN: ESSN 1362-4962
PubMed: 39287137
DOI: 10.1093/NAR/GKAE805
Page generated: Fri Aug 8 00:00:29 2025

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