Iron in PDB 8uot: Composite Map of Picdeltatfiik FORM1

All present enzymatic activity of Composite Map of Picdeltatfiik FORM1:
2.7.7.6; 3.6.4.12; 5.6.2.3;

The structure of Composite Map of Picdeltatfiik FORM1 also contains other interesting chemical elements:

Zinc	(Zn)	15 atoms
Magnesium	(Mg)	2 atoms

The binding sites of Iron atom in the Composite Map of Picdeltatfiik FORM1 (pdb code 8uot). This binding sites where shown within 5.0 Angstroms radius around Iron atom.
In total 4 binding sites of Iron where determined in the Composite Map of Picdeltatfiik FORM1, PDB code: 8uot:
Jump to Iron binding site number: 1; 2; 3; 4;

Iron binding site 1 out of 4 in the Composite Map of Picdeltatfiik FORM1


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 1 of Composite Map of Picdeltatfiik FORM1 within 5.0Å range: probe atom residue distance (Å) B Occ 0:Fe801 b:223.7 occ:1.00 FE1 0:SF4801 0.0 223.7 1.0 SG 0:CYS115 1.2 131.2 1.0 S2 0:SF4801 2.2 223.7 1.0 S3 0:SF4801 2.2 223.7 1.0 S4 0:SF4801 2.3 223.7 1.0 CB 0:CYS115 2.5 131.2 1.0 FE4 0:SF4801 2.7 223.7 1.0 FE3 0:SF4801 2.7 223.7 1.0 FE2 0:SF4801 2.7 223.7 1.0 CA 0:CYS115 3.0 131.2 1.0 SG 0:CYS191 3.3 163.4 1.0 C 0:CYS115 3.5 131.2 1.0 N 0:LEU116 3.7 118.0 1.0 S1 0:SF4801 3.8 223.7 1.0 N 0:HIS117 3.9 115.0 1.0 NE 0:ARG111 4.0 173.3 1.0 CD 0:ARG111 4.1 173.3 1.0 CB 0:HIS117 4.1 115.0 1.0 O 0:CYS115 4.3 131.2 1.0 N 0:CYS115 4.4 131.2 1.0 CB 0:CYS191 4.5 163.4 1.0 SG 0:CYS133 4.5 154.3 1.0 CG 0:ARG111 4.5 173.3 1.0 CA 0:HIS117 4.7 115.0 1.0 SG 0:CYS156 4.7 151.3 1.0 C 0:LEU116 4.9 118.0 1.0 CA 0:LEU116 4.9 118.0 1.0

Iron binding site 2 out of 4 in the Composite Map of Picdeltatfiik FORM1


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 2 of Composite Map of Picdeltatfiik FORM1 within 5.0Å range: probe atom residue distance (Å) B Occ 0:Fe801 b:223.7 occ:1.00 FE2 0:SF4801 0.0 223.7 1.0 SG 0:CYS156 2.2 151.3 1.0 S3 0:SF4801 2.3 223.7 1.0 S4 0:SF4801 2.3 223.7 1.0 S1 0:SF4801 2.3 223.7 1.0 FE1 0:SF4801 2.7 223.7 1.0 FE4 0:SF4801 2.8 223.7 1.0 FE3 0:SF4801 2.8 223.7 1.0 CB 0:HIS117 3.0 115.0 1.0 CB 0:CYS156 3.2 151.3 1.0 SG 0:CYS115 3.2 131.2 1.0 ND1 0:HIS117 3.3 115.0 1.0 CG 0:HIS117 3.4 115.0 1.0 S2 0:SF4801 3.9 223.7 1.0 CA 0:HIS117 4.0 115.0 1.0 N 0:HIS117 4.1 115.0 1.0 CE1 0:HIS117 4.4 115.0 1.0 CA 0:CYS156 4.5 151.3 1.0 SG 0:CYS133 4.6 154.3 1.0 CD1 0:TYR158 4.6 151.8 1.0 CD2 0:HIS117 4.6 115.0 1.0 SD 0:MET136 4.6 163.1 1.0 SG 0:CYS191 4.8 163.4 1.0 CB 0:TYR158 4.9 151.8 1.0 CB 0:CYS115 4.9 131.2 1.0

Iron binding site 3 out of 4 in the Composite Map of Picdeltatfiik FORM1


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 3 of Composite Map of Picdeltatfiik FORM1 within 5.0Å range: probe atom residue distance (Å) B Occ 0:Fe801 b:223.7 occ:1.00 FE3 0:SF4801 0.0 223.7 1.0 SG 0:CYS133 2.2 154.3 1.0 S1 0:SF4801 2.3 223.7 1.0 S4 0:SF4801 2.3 223.7 1.0 S2 0:SF4801 2.3 223.7 1.0 FE1 0:SF4801 2.7 223.7 1.0 FE4 0:SF4801 2.7 223.7 1.0 FE2 0:SF4801 2.8 223.7 1.0 NE 0:ARG111 3.2 173.3 1.0 SG 0:CYS115 3.2 131.2 1.0 CB 0:CYS133 3.6 154.3 1.0 CE2 0:PHE194 3.7 173.8 1.0 S3 0:SF4801 3.9 223.7 1.0 SG 0:CYS191 3.9 163.4 1.0 NH2 0:ARG111 4.0 173.3 1.0 CD 0:ARG111 4.0 173.3 1.0 CZ 0:ARG111 4.0 173.3 1.0 OG1 0:THR137 4.2 145.8 1.0 CD2 0:PHE194 4.3 173.8 1.0 SG 0:CYS156 4.4 151.3 1.0 CA 0:CYS133 4.5 154.3 1.0 CZ 0:PHE194 4.5 173.8 1.0 NH2 0:ARG134 4.6 165.7 1.0 CB 0:CYS115 4.7 131.2 1.0 CB 0:CYS156 4.7 151.3 1.0 CB 0:CYS191 4.8 163.4 1.0 CG2 0:THR137 4.9 145.8 1.0 O 0:CYS133 5.0 154.3 1.0 CG 0:ARG111 5.0 173.3 1.0

Iron binding site 4 out of 4 in the Composite Map of Picdeltatfiik FORM1


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 4 of Composite Map of Picdeltatfiik FORM1 within 5.0Å range: probe atom residue distance (Å) B Occ 0:Fe801 b:223.7 occ:1.00 FE4 0:SF4801 0.0 223.7 1.0 SG 0:CYS191 2.2 163.4 1.0 S3 0:SF4801 2.3 223.7 1.0 S1 0:SF4801 2.3 223.7 1.0 S2 0:SF4801 2.3 223.7 1.0 CB 0:CYS191 2.4 163.4 1.0 FE1 0:SF4801 2.7 223.7 1.0 FE3 0:SF4801 2.7 223.7 1.0 FE2 0:SF4801 2.8 223.7 1.0 SG 0:CYS156 3.6 151.3 1.0 CA 0:CYS191 3.6 163.4 1.0 CD2 0:PHE194 3.8 173.8 1.0 SG 0:CYS115 3.8 131.2 1.0 S4 0:SF4801 3.9 223.7 1.0 CE2 0:PHE194 3.9 173.8 1.0 CB 0:TYR158 4.0 151.8 1.0 N 0:CYS191 4.4 163.4 1.0 N 0:HIS159 4.5 184.4 1.0 CB 0:CYS156 4.6 151.3 1.0 CB 0:HIS159 4.7 184.4 1.0 C 0:CYS191 4.7 163.4 1.0 CG 0:TYR158 4.7 151.8 1.0 NE 0:ARG111 4.9 173.3 1.0 SG 0:CYS133 4.9 154.3 1.0 CD1 0:TYR158 5.0 151.8 1.0 C 0:TYR158 5.0 151.8 1.0

C.Yang, P.Basnet, S.Sharmin, H.Shen, C.D.Kaplan, K.Murakami. Transcription Start Site Scanning Requires the Fungi-Specific Hydrophobic Loop of TFB3. Nucleic Acids Res. 2024.
ISSN: ESSN 1362-4962
PubMed: 39287137
DOI: 10.1093/NAR/GKAE805