Iron in PDB 9c7t: PP2A:B55-EYA3 Substrate Complex

All present enzymatic activity of PP2A:B55-EYA3 Substrate Complex:
3.1.3.16; 3.1.3.48;

The structure of PP2A:B55-EYA3 Substrate Complex also contains other interesting chemical elements:

Zinc

(Zn)

1 atom

The binding sites of Iron atom in the PP2A:B55-EYA3 Substrate Complex (pdb code 9c7t). This binding sites where shown within 5.0 Angstroms radius around Iron atom.
In total only one binding site of Iron was determined in the PP2A:B55-EYA3 Substrate Complex, PDB code: 9c7t:

Iron binding site 1 out of 1 in the PP2A:B55-EYA3 Substrate Complex


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 1 of PP2A:B55-EYA3 Substrate Complex within 5.0Å range: probe atom residue distance (Å) B Occ C:Fe401 b:112.3 occ:1.00 OD2 C:ASP85 2.0 99.5 1.0 ND1 C:HIS241 2.0 104.7 1.0 NE2 C:HIS167 2.1 101.1 1.0 OD1 C:ASN117 2.1 104.3 1.0 CG C:ASP85 2.7 99.5 1.0 ZN C:ZN402 2.7 113.2 1.0 CE1 C:HIS241 2.9 104.7 1.0 CE1 C:HIS167 2.9 101.1 1.0 CG C:HIS241 2.9 104.7 1.0 OD1 C:ASP85 3.0 99.5 1.0 CD2 C:HIS167 3.1 101.1 1.0 CG C:ASN117 3.2 104.3 1.0 CB C:HIS241 3.4 104.7 1.0 CA C:HIS241 3.7 104.7 1.0 NE2 C:HIS241 3.9 104.7 1.0 CD2 C:HIS241 3.9 104.7 1.0 ND2 C:ASN117 3.9 104.3 1.0 CB C:ASP85 4.0 99.5 1.0 ND1 C:HIS167 4.1 101.1 1.0 OD2 C:ASP57 4.2 93.5 1.0 CD2 C:HIS118 4.2 103.7 1.0 CG C:HIS167 4.2 101.1 1.0 CB C:ASN117 4.2 104.3 1.0 N C:ASN117 4.3 104.3 1.0 NE2 C:HIS59 4.4 96.3 1.0 OD1 C:ASP57 4.4 93.5 1.0 O C:HIS241 4.4 104.7 1.0 CG C:ASP57 4.6 93.5 1.0 C C:HIS241 4.6 104.7 1.0 CE1 C:HIS59 4.7 96.3 1.0 N C:HIS241 4.8 104.7 1.0 CA C:ASN117 4.8 104.3 1.0 NE2 C:HIS118 4.9 103.7 1.0 N C:HIS118 5.0 103.7 1.0

S.K.R.Padi, R.J.Godek, W.Peti, R.Page. Cryo-Em Structures of PP2A:B55 with P107 and EYA3 Define Substrate Recruitment. Nat.Struct.Mol.Biol. 2025.
ISSN: ESSN 1545-9985
PubMed: 40247147
DOI: 10.1038/S41594-025-01535-3