Iron in PDB 9lxo: Human Rna Polymerase III De Novo Transcribing Complex 6 (TC6)(Without 3'Datp)

All present enzymatic activity of Human Rna Polymerase III De Novo Transcribing Complex 6 (TC6)(Without 3'Datp):
2.7.7.6;

The structure of Human Rna Polymerase III De Novo Transcribing Complex 6 (TC6)(Without 3'Datp) also contains other interesting chemical elements:

Magnesium	(Mg)	1 atom
Zinc	(Zn)	6 atoms

The binding sites of Iron atom in the Human Rna Polymerase III De Novo Transcribing Complex 6 (TC6)(Without 3'Datp) (pdb code 9lxo). This binding sites where shown within 5.0 Angstroms radius around Iron atom.
In total 4 binding sites of Iron where determined in the Human Rna Polymerase III De Novo Transcribing Complex 6 (TC6)(Without 3'Datp), PDB code: 9lxo:
Jump to Iron binding site number: 1; 2; 3; 4;

Iron binding site 1 out of 4 in the Human Rna Polymerase III De Novo Transcribing Complex 6 (TC6)(Without 3'Datp)


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 1 of Human Rna Polymerase III De Novo Transcribing Complex 6 (TC6)(Without 3'Datp) within 5.0Å range: probe atom residue distance (Å) B Occ P:Fe401 b:101.0 occ:1.00 FE1 P:SF4401 0.0 101.0 1.0 S4 P:SF4401 2.3 101.0 1.0 S3 P:SF4401 2.3 101.0 1.0 S2 P:SF4401 2.3 101.0 1.0 FE3 P:SF4401 2.7 101.0 1.0 FE2 P:SF4401 2.7 101.0 1.0 FE4 P:SF4401 2.7 101.0 1.0 SG P:CYS290 3.3 103.3 1.0 CD2 P:TYR309 3.4 111.4 1.0 SG P:CYS307 3.5 108.3 1.0 CB P:CYS290 3.8 103.3 1.0 S1 P:SF4401 3.9 101.0 1.0 CG P:TYR309 4.0 111.4 1.0 CE2 P:TYR309 4.1 111.4 1.0 CB P:TYR309 4.2 111.4 1.0 O P:PRO286 4.6 105.3 1.0 CB P:CYS307 4.9 108.3 1.0 CA P:CYS287 5.0 106.3 1.0

Iron binding site 2 out of 4 in the Human Rna Polymerase III De Novo Transcribing Complex 6 (TC6)(Without 3'Datp)


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 2 of Human Rna Polymerase III De Novo Transcribing Complex 6 (TC6)(Without 3'Datp) within 5.0Å range: probe atom residue distance (Å) B Occ P:Fe401 b:101.0 occ:1.00 FE2 P:SF4401 0.0 101.0 1.0 S1 P:SF4401 2.3 101.0 1.0 S3 P:SF4401 2.3 101.0 1.0 S4 P:SF4401 2.3 101.0 1.0 FE3 P:SF4401 2.7 101.0 1.0 FE4 P:SF4401 2.7 101.0 1.0 FE1 P:SF4401 2.7 101.0 1.0 S2 P:SF4401 3.9 101.0 1.0 SG P:CYS296 4.0 104.5 1.0 CB P:CYS296 4.0 104.5 1.0 CG2 P:ILE302 4.2 107.9 1.0 SG P:CYS290 4.5 103.3 1.0 SG P:CYS307 4.6 108.3 1.0 CA P:CYS296 4.7 104.5 1.0 ND2 O:ASN445 4.9 104.9 1.0

Iron binding site 3 out of 4 in the Human Rna Polymerase III De Novo Transcribing Complex 6 (TC6)(Without 3'Datp)


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 3 of Human Rna Polymerase III De Novo Transcribing Complex 6 (TC6)(Without 3'Datp) within 5.0Å range: probe atom residue distance (Å) B Occ P:Fe401 b:101.0 occ:1.00 FE3 P:SF4401 0.0 101.0 1.0 S1 P:SF4401 2.3 101.0 1.0 S4 P:SF4401 2.3 101.0 1.0 S2 P:SF4401 2.3 101.0 1.0 FE2 P:SF4401 2.7 101.0 1.0 FE1 P:SF4401 2.7 101.0 1.0 FE4 P:SF4401 2.7 101.0 1.0 SG P:CYS287 3.2 106.3 1.0 CB P:CYS287 3.8 106.3 1.0 CA P:CYS287 3.8 106.3 1.0 S3 P:SF4401 3.9 101.0 1.0 ND2 O:ASN445 4.2 104.9 1.0 N P:CYS287 4.3 106.3 1.0 CE P:MET310 4.3 117.8 1.0 CB O:ASN445 4.5 104.9 1.0 SG P:CYS307 4.5 108.3 1.0 SD P:MET310 4.6 117.8 1.0 CG O:ASN445 4.7 104.9 1.0 CG P:MET310 4.7 117.8 1.0 C P:PRO286 4.8 105.3 1.0 O P:PRO286 5.0 105.3 1.0

Iron binding site 4 out of 4 in the Human Rna Polymerase III De Novo Transcribing Complex 6 (TC6)(Without 3'Datp)


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 4 of Human Rna Polymerase III De Novo Transcribing Complex 6 (TC6)(Without 3'Datp) within 5.0Å range: probe atom residue distance (Å) B Occ P:Fe401 b:101.0 occ:1.00 FE4 P:SF4401 0.0 101.0 1.0 SG P:CYS307 2.2 108.3 1.0 S1 P:SF4401 2.3 101.0 1.0 S2 P:SF4401 2.3 101.0 1.0 S3 P:SF4401 2.3 101.0 1.0 CB P:CYS307 2.6 108.3 1.0 FE2 P:SF4401 2.7 101.0 1.0 FE1 P:SF4401 2.7 101.0 1.0 FE3 P:SF4401 2.7 101.0 1.0 CE P:MET310 3.5 117.8 1.0 S4 P:SF4401 3.9 101.0 1.0 CA P:CYS307 4.0 108.3 1.0 CA P:PRO304 4.1 105.5 1.0 O P:SER303 4.4 107.8 1.0 CG P:MET310 4.5 117.8 1.0 SD P:MET310 4.6 117.8 1.0 N P:PRO304 4.7 105.5 1.0 CB P:PRO304 4.8 105.5 1.0 C P:SER303 4.8 107.8 1.0 O P:PRO304 4.8 105.5 1.0 CD2 P:TYR309 4.9 111.4 1.0 N P:CYS307 4.9 108.3 1.0 C P:PRO304 4.9 105.5 1.0 C P:CYS307 4.9 108.3 1.0

Q.Wang, Y.Ren, Q.Jin, X.Chen, Y.Xu. Human Rna Polymerase III De Novo Transcribing Complex 5 (TC5)(Without 3'Datp) To Be Published.