Iron in PDB 1a4e: Catalase A From Saccharomyces Cerevisiae

All present enzymatic activity of Catalase A From Saccharomyces Cerevisiae:
1.11.1.6;

The structure of Catalase A From Saccharomyces Cerevisiae, PDB code: 1a4e was solved by M.J.Mate, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	20.00 / 2.40
Space group	P 61 2 2
Cell size a, b, c (Å), α, β, γ (°)	184.172, 184.172, 304.977, 90.00, 90.00, 120.00
R / Rfree (%)	15.4 / 19.8

The binding sites of Iron atom in the Catalase A From Saccharomyces Cerevisiae (pdb code 1a4e). This binding sites where shown within 5.0 Angstroms radius around Iron atom.
In total 4 binding sites of Iron where determined in the Catalase A From Saccharomyces Cerevisiae, PDB code: 1a4e:
Jump to Iron binding site number: 1; 2; 3; 4;

Iron binding site 1 out of 4 in the Catalase A From Saccharomyces Cerevisiae


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 1 of Catalase A From Saccharomyces Cerevisiae within 5.0Å range: probe atom residue distance (Å) B Occ A:Fe503 b:23.1 occ:1.00 FE A:HEM503 0.0 23.1 1.0 OH A:TYR355 1.9 21.0 1.0 ND A:HEM503 1.9 21.7 1.0 NB A:HEM503 2.0 22.0 1.0 NC A:HEM503 2.0 23.9 1.0 NA A:HEM503 2.0 26.2 1.0 N1 A:AZI504 2.1 28.3 1.0 CZ A:TYR355 3.0 21.3 1.0 C4D A:HEM503 3.0 23.4 1.0 C1D A:HEM503 3.0 24.7 1.0 C1B A:HEM503 3.0 25.6 1.0 C4B A:HEM503 3.0 23.9 1.0 C4C A:HEM503 3.0 24.6 1.0 C1C A:HEM503 3.0 21.7 1.0 C4A A:HEM503 3.0 24.0 1.0 C1A A:HEM503 3.0 24.1 1.0 N2 A:AZI504 3.1 25.5 1.0 CHD A:HEM503 3.4 24.0 1.0 CHC A:HEM503 3.4 23.2 1.0 CHA A:HEM503 3.4 21.9 1.0 CHB A:HEM503 3.4 24.3 1.0 CE2 A:TYR355 3.7 18.1 1.0 CE1 A:TYR355 3.8 19.0 1.0 NE A:ARG351 4.2 19.4 1.0 C3D A:HEM503 4.2 22.0 1.0 C2D A:HEM503 4.2 22.6 1.0 C3A A:HEM503 4.3 24.5 1.0 C2B A:HEM503 4.3 20.2 1.0 C2A A:HEM503 4.3 23.8 1.0 C2C A:HEM503 4.3 24.9 1.0 C3C A:HEM503 4.3 24.6 1.0 C3B A:HEM503 4.3 23.2 1.0 N3 A:AZI504 4.3 28.5 1.0 NH2 A:ARG351 4.4 16.2 1.0 CZ A:PHE156 4.5 29.3 1.0 NE2 A:HIS70 4.7 24.9 1.0 CZ A:ARG351 4.7 19.6 1.0 CD2 A:HIS70 4.8 23.6 1.0 CE1 A:PHE156 4.9 28.1 1.0 CD A:PRO69 4.9 24.4 1.0 CD2 A:TYR355 5.0 15.3 1.0

Iron binding site 2 out of 4 in the Catalase A From Saccharomyces Cerevisiae


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 2 of Catalase A From Saccharomyces Cerevisiae within 5.0Å range: probe atom residue distance (Å) B Occ B:Fe503 b:20.8 occ:1.00 FE B:HEM503 0.0 20.8 1.0 OH B:TYR355 1.9 17.2 1.0 ND B:HEM503 2.0 20.6 1.0 NB B:HEM503 2.0 23.4 1.0 NA B:HEM503 2.0 23.4 1.0 NC B:HEM503 2.0 24.8 1.0 N1 B:AZI504 2.1 25.3 1.0 N2 B:AZI504 3.0 27.5 1.0 CZ B:TYR355 3.0 22.7 1.0 C4D B:HEM503 3.0 20.8 1.0 C1B B:HEM503 3.0 24.7 1.0 C1C B:HEM503 3.0 23.5 1.0 C4A B:HEM503 3.0 24.6 1.0 C4B B:HEM503 3.0 22.1 1.0 C1D B:HEM503 3.0 20.6 1.0 C1A B:HEM503 3.0 21.8 1.0 C4C B:HEM503 3.0 24.4 1.0 CHC B:HEM503 3.4 22.8 1.0 CHB B:HEM503 3.4 23.1 1.0 CHA B:HEM503 3.4 19.7 1.0 CHD B:HEM503 3.4 22.3 1.0 CE2 B:TYR355 3.8 19.3 1.0 CE1 B:TYR355 3.8 20.6 1.0 N3 B:AZI504 4.1 27.8 1.0 NE B:ARG351 4.2 22.8 1.0 C3D B:HEM503 4.2 21.9 1.0 C2D B:HEM503 4.2 20.6 1.0 C3A B:HEM503 4.2 24.2 1.0 C2C B:HEM503 4.2 25.6 1.0 C2B B:HEM503 4.3 24.3 1.0 C2A B:HEM503 4.3 23.9 1.0 C3C B:HEM503 4.3 24.9 1.0 C3B B:HEM503 4.3 25.4 1.0 NH2 B:ARG351 4.3 22.5 1.0 CZ B:PHE156 4.6 23.2 1.0 CZ B:ARG351 4.7 21.6 1.0 NE2 B:HIS70 4.7 24.5 1.0 CD2 B:HIS70 4.8 24.0 1.0 CE1 B:PHE156 5.0 23.9 1.0

Iron binding site 3 out of 4 in the Catalase A From Saccharomyces Cerevisiae


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 3 of Catalase A From Saccharomyces Cerevisiae within 5.0Å range: probe atom residue distance (Å) B Occ C:Fe503 b:21.0 occ:1.00 FE C:HEM503 0.0 21.0 1.0 OH C:TYR355 1.9 19.7 1.0 ND C:HEM503 2.0 21.8 1.0 NC C:HEM503 2.0 22.2 1.0 NB C:HEM503 2.0 21.2 1.0 NA C:HEM503 2.0 23.4 1.0 N1 C:AZI504 2.1 22.4 1.0 CZ C:TYR355 3.0 21.5 1.0 C4D C:HEM503 3.0 20.7 1.0 C1D C:HEM503 3.0 22.8 1.0 C4C C:HEM503 3.0 24.6 1.0 C1C C:HEM503 3.0 24.0 1.0 C1B C:HEM503 3.0 22.9 1.0 C4B C:HEM503 3.0 21.1 1.0 C1A C:HEM503 3.0 22.4 1.0 C4A C:HEM503 3.0 22.8 1.0 N2 C:AZI504 3.1 21.3 1.0 CHD C:HEM503 3.4 23.2 1.0 CHA C:HEM503 3.4 21.4 1.0 CHC C:HEM503 3.4 23.7 1.0 CHB C:HEM503 3.4 21.2 1.0 CE2 C:TYR355 3.7 20.2 1.0 CE1 C:TYR355 3.9 20.6 1.0 NE C:ARG351 4.1 21.9 1.0 C3D C:HEM503 4.2 20.3 1.0 C2D C:HEM503 4.2 19.3 1.0 C2C C:HEM503 4.2 25.7 1.0 C3C C:HEM503 4.3 25.9 1.0 C3A C:HEM503 4.3 21.9 1.0 C2B C:HEM503 4.3 18.8 1.0 C2A C:HEM503 4.3 24.4 1.0 NH2 C:ARG351 4.3 17.3 1.0 C3B C:HEM503 4.3 21.4 1.0 N3 C:AZI504 4.3 20.5 1.0 CZ C:PHE156 4.5 22.1 1.0 CZ C:ARG351 4.6 22.3 1.0 NE2 C:HIS70 4.8 25.9 1.0 CD2 C:HIS70 4.8 24.7 1.0 CE1 C:PHE156 4.9 21.3 1.0 CD2 C:TYR355 5.0 18.7 1.0

Iron binding site 4 out of 4 in the Catalase A From Saccharomyces Cerevisiae


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 4 of Catalase A From Saccharomyces Cerevisiae within 5.0Å range: probe atom residue distance (Å) B Occ D:Fe503 b:24.2 occ:1.00 FE D:HEM503 0.0 24.2 1.0 OH D:TYR355 1.9 23.0 1.0 ND D:HEM503 2.0 26.4 1.0 NA D:HEM503 2.0 27.8 1.0 NB D:HEM503 2.0 25.6 1.0 NC D:HEM503 2.0 28.8 1.0 N1 D:AZI504 2.1 28.0 1.0 N2 D:AZI504 2.9 28.3 1.0 C1D D:HEM503 3.0 26.5 1.0 C1B D:HEM503 3.0 24.2 1.0 C4D D:HEM503 3.0 27.5 1.0 C4A D:HEM503 3.0 27.3 1.0 C1A D:HEM503 3.0 27.4 1.0 C4C D:HEM503 3.0 27.2 1.0 C1C D:HEM503 3.0 27.6 1.0 C4B D:HEM503 3.0 26.6 1.0 CZ D:TYR355 3.0 25.2 1.0 CHD D:HEM503 3.4 27.9 1.0 CHB D:HEM503 3.4 24.9 1.0 CHA D:HEM503 3.4 26.5 1.0 CHC D:HEM503 3.4 24.6 1.0 CE2 D:TYR355 3.8 23.1 1.0 CE1 D:TYR355 3.9 24.7 1.0 N3 D:AZI504 4.1 32.1 1.0 NE D:ARG351 4.1 24.2 1.0 C3A D:HEM503 4.2 26.0 1.0 C2A D:HEM503 4.2 27.2 1.0 C2B D:HEM503 4.2 25.3 1.0 C2D D:HEM503 4.2 24.8 1.0 C3D D:HEM503 4.3 26.8 1.0 C2C D:HEM503 4.3 28.1 1.0 C3C D:HEM503 4.3 28.9 1.0 C3B D:HEM503 4.3 27.0 1.0 NH2 D:ARG351 4.3 25.1 1.0 CZ D:PHE156 4.5 30.4 1.0 CZ D:ARG351 4.6 27.4 1.0 NE2 D:HIS70 4.7 28.6 1.0 CD2 D:HIS70 4.8 27.6 1.0 CE1 D:PHE156 4.9 26.4 1.0

M.J.Mate, M.Zamocky, L.M.Nykyri, C.Herzog, P.M.Alzari, C.Betzel, F.Koller, I.Fita. Structure of Catalase-A From Saccharomyces Cerevisiae. J.Mol.Biol. V. 286 135 1999.
ISSN: ISSN 0022-2836
PubMed: 9931255
DOI: 10.1006/JMBI.1998.2453