Atomistry » Iron » PDB 1a9w-1aop » 1aa6
Atomistry »
  Iron »
    PDB 1a9w-1aop »
      1aa6 »

Iron in PDB 1aa6: Reduced Form of Formate Dehydrogenase H From E. Coli

Enzymatic activity of Reduced Form of Formate Dehydrogenase H From E. Coli

All present enzymatic activity of Reduced Form of Formate Dehydrogenase H From E. Coli:
1.2.1.2;

Protein crystallography data

The structure of Reduced Form of Formate Dehydrogenase H From E. Coli, PDB code: 1aa6 was solved by P.D.Sun, J.C.Boyington, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 6.00 / 2.30
Space group P 41 21 2
Cell size a, b, c (Å), α, β, γ (°) 146.400, 146.400, 82.700, 90.00, 90.00, 90.00
R / Rfree (%) 21.7 / 28.7

Other elements in 1aa6:

The structure of Reduced Form of Formate Dehydrogenase H From E. Coli also contains other interesting chemical elements:

Molybdenum (Mo) 1 atom

Iron Binding Sites:

The binding sites of Iron atom in the Reduced Form of Formate Dehydrogenase H From E. Coli (pdb code 1aa6). This binding sites where shown within 5.0 Angstroms radius around Iron atom.
In total 4 binding sites of Iron where determined in the Reduced Form of Formate Dehydrogenase H From E. Coli, PDB code: 1aa6:
Jump to Iron binding site number: 1; 2; 3; 4;

Iron binding site 1 out of 4 in 1aa6

Go back to Iron Binding Sites List in 1aa6
Iron binding site 1 out of 4 in the Reduced Form of Formate Dehydrogenase H From E. Coli


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 1 of Reduced Form of Formate Dehydrogenase H From E. Coli within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Fe800

b:19.6
occ:1.00
FE1 A:SF4800 0.0 19.6 1.0
SG A:CYS42 2.3 15.1 1.0
S2 A:SF4800 2.3 17.3 1.0
S3 A:SF4800 2.3 15.7 1.0
S4 A:SF4800 2.3 16.4 1.0
FE2 A:SF4800 2.7 17.9 1.0
FE4 A:SF4800 2.7 17.0 1.0
FE3 A:SF4800 2.8 19.3 1.0
CB A:CYS42 3.3 19.3 1.0
N A:CYS42 3.8 19.8 1.0
S1 A:SF4800 3.9 16.3 1.0
CA A:CYS42 4.1 20.1 1.0
N A:GLY45 4.4 19.1 1.0
CD A:PRO182 4.5 14.6 1.0
C A:CYS42 4.5 20.9 1.0
CG A:PRO182 4.6 13.8 1.0
O A:CYS42 4.6 21.6 1.0
NZ A:LYS44 4.6 28.1 1.0
CE A:LYS44 4.6 26.6 1.0
CB A:PRO182 4.7 13.0 1.0
CB A:LYS44 4.7 20.5 1.0
SG A:CYS8 4.8 18.6 1.0
O A:HOH833 4.8 22.3 1.0
SG A:CYS11 4.8 13.9 1.0
SG A:CYS15 4.9 17.0 1.0
N A:LYS44 4.9 21.2 1.0
C A:LEU41 5.0 20.5 1.0

Iron binding site 2 out of 4 in 1aa6

Go back to Iron Binding Sites List in 1aa6
Iron binding site 2 out of 4 in the Reduced Form of Formate Dehydrogenase H From E. Coli


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 2 of Reduced Form of Formate Dehydrogenase H From E. Coli within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Fe800

b:17.9
occ:1.00
FE2 A:SF4800 0.0 17.9 1.0
S1 A:SF4800 2.2 16.3 1.0
SG A:CYS8 2.3 18.6 1.0
S3 A:SF4800 2.3 15.7 1.0
S4 A:SF4800 2.4 16.4 1.0
FE3 A:SF4800 2.6 19.3 1.0
FE4 A:SF4800 2.7 17.0 1.0
FE1 A:SF4800 2.7 19.6 1.0
CB A:CYS8 3.1 16.5 1.0
S2 A:SF4800 3.8 17.3 1.0
CB A:TYR10 4.2 14.4 1.0
N A:GLY45 4.3 19.1 1.0
CA A:GLY45 4.3 20.4 1.0
CA A:CYS8 4.5 16.6 1.0
SG A:CYS15 4.6 17.0 1.0
N A:CYS11 4.6 12.6 1.0
CB A:CYS15 4.6 12.8 1.0
SG A:CYS42 4.7 15.1 1.0
CD2 A:TYR10 4.8 14.9 1.0
SG A:CYS11 4.9 13.9 1.0
N A:TYR10 4.9 12.9 1.0
O A:CYS11 4.9 11.1 1.0
CA A:TYR10 5.0 14.5 1.0

Iron binding site 3 out of 4 in 1aa6

Go back to Iron Binding Sites List in 1aa6
Iron binding site 3 out of 4 in the Reduced Form of Formate Dehydrogenase H From E. Coli


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 3 of Reduced Form of Formate Dehydrogenase H From E. Coli within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Fe800

b:19.3
occ:1.00
FE3 A:SF4800 0.0 19.3 1.0
SG A:CYS15 2.2 17.0 1.0
S2 A:SF4800 2.3 17.3 1.0
S4 A:SF4800 2.3 16.4 1.0
S1 A:SF4800 2.3 16.3 1.0
FE2 A:SF4800 2.6 17.9 1.0
FE4 A:SF4800 2.8 17.0 1.0
FE1 A:SF4800 2.8 19.6 1.0
CB A:CYS15 3.2 12.8 1.0
S3 A:SF4800 4.0 15.7 1.0
CB A:SER13 4.0 10.4 1.0
N A:CYS15 4.3 15.2 1.0
CD1 A:ILE183 4.3 10.2 1.0
CA A:CYS15 4.3 14.8 1.0
CG1 A:ILE183 4.3 11.8 1.0
CB A:ILE183 4.4 12.4 1.0
CB A:CYS8 4.5 16.5 1.0
SG A:CYS8 4.6 18.6 1.0
OG A:SER13 4.6 12.1 1.0
N A:CYS42 4.8 19.8 1.0
SG A:CYS11 4.9 13.9 1.0
CD2 A:LEU41 4.9 20.0 1.0

Iron binding site 4 out of 4 in 1aa6

Go back to Iron Binding Sites List in 1aa6
Iron binding site 4 out of 4 in the Reduced Form of Formate Dehydrogenase H From E. Coli


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 4 of Reduced Form of Formate Dehydrogenase H From E. Coli within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Fe800

b:17.0
occ:1.00
FE4 A:SF4800 0.0 17.0 1.0
S3 A:SF4800 2.3 15.7 1.0
S1 A:SF4800 2.3 16.3 1.0
S2 A:SF4800 2.3 17.3 1.0
SG A:CYS11 2.4 13.9 1.0
FE2 A:SF4800 2.7 17.9 1.0
FE1 A:SF4800 2.7 19.6 1.0
FE3 A:SF4800 2.8 19.3 1.0
CB A:CYS11 3.5 12.7 1.0
N A:CYS11 3.9 12.6 1.0
CB A:SER13 3.9 10.4 1.0
OG A:SER13 3.9 12.1 1.0
S4 A:SF4800 4.0 16.4 1.0
CA A:CYS11 4.0 12.7 1.0
O A:HOH833 4.0 22.3 1.0
O A:CYS11 4.0 11.1 1.0
C A:CYS11 4.2 12.4 1.0
N A:SER13 4.5 12.7 1.0
CD A:PRO182 4.6 14.6 1.0
SG A:CYS8 4.6 18.6 1.0
NZ A:LYS44 4.7 28.1 1.0
SG A:CYS42 4.7 15.1 1.0
SG A:CYS15 4.8 17.0 1.0
CA A:SER13 4.8 12.9 1.0
CB A:TYR10 4.8 14.4 1.0

Reference:

J.C.Boyington, V.N.Gladyshev, S.V.Khangulov, T.C.Stadtman, P.D.Sun. Crystal Structure of Formate Dehydrogenase H: Catalysis Involving Mo, Molybdopterin, Selenocysteine, and An FE4S4 Cluster. Science V. 275 1305 1997.
ISSN: ISSN 0036-8075
PubMed: 9036855
DOI: 10.1126/SCIENCE.275.5304.1305
Page generated: Sun Dec 13 14:03:35 2020

Last articles

Zn in 7O75
Zn in 7O73
Zn in 7O4I
Zn in 7O72
Zn in 7O4J
Zn in 7NVR
Zn in 7NVY
Zn in 7NVZ
Zn in 7NW0
Zn in 7O4K
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy