Iron in PDB 1ep1: Crystal Structure of Lactococcus Lactis Dihydroorotate Dehydrogenase B

All present enzymatic activity of Crystal Structure of Lactococcus Lactis Dihydroorotate Dehydrogenase B:
1.3.3.1;

The structure of Crystal Structure of Lactococcus Lactis Dihydroorotate Dehydrogenase B, PDB code: 1ep1 was solved by P.Rowland, S.Norager, K.F.Jensen, S.Larsen, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	30.70 / 2.20
Space group	H 3 2
Cell size a, b, c (Å), α, β, γ (°)	202.670, 202.670, 81.110, 90.00, 90.00, 120.00
R / Rfree (%)	20.2 / 25.6

The binding sites of Iron atom in the Crystal Structure of Lactococcus Lactis Dihydroorotate Dehydrogenase B (pdb code 1ep1). This binding sites where shown within 5.0 Angstroms radius around Iron atom.
In total 2 binding sites of Iron where determined in the Crystal Structure of Lactococcus Lactis Dihydroorotate Dehydrogenase B, PDB code: 1ep1:
Jump to Iron binding site number: 1; 2;

Iron binding site 1 out of 2 in the Crystal Structure of Lactococcus Lactis Dihydroorotate Dehydrogenase B


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 1 of Crystal Structure of Lactococcus Lactis Dihydroorotate Dehydrogenase B within 5.0Å range: probe atom residue distance (Å) B Occ B:Fe503 b:32.0 occ:1.00 FE1 B:FES503 0.0 32.0 1.0 S2 B:FES503 2.2 32.4 1.0 SG B:CYS231 2.2 33.4 1.0 S1 B:FES503 2.3 31.5 1.0 SG B:CYS226 2.3 27.4 1.0 FE2 B:FES503 2.7 32.2 1.0 CB B:CYS231 3.4 31.1 1.0 CB B:CYS226 3.4 25.5 1.0 N B:CYS226 3.5 27.2 1.0 N B:CYS231 3.6 33.0 1.0 N B:GLY227 3.6 32.6 1.0 N B:TYR232 3.8 36.9 1.0 CA B:CYS231 3.8 33.0 1.0 CA B:CYS226 3.9 28.4 1.0 N B:ALA233 4.2 37.2 1.0 C B:CYS231 4.2 35.9 1.0 C B:CYS226 4.2 30.1 1.0 SG B:CYS249 4.2 34.3 1.0 N B:GLY229 4.3 29.3 1.0 N B:ALA230 4.4 29.0 1.0 CB B:ALA233 4.4 36.7 1.0 N B:ALA225 4.5 25.7 1.0 CA B:GLY227 4.6 34.0 1.0 C B:ALA225 4.6 24.9 1.0 N B:ILE228 4.6 31.7 1.0 SG B:CYS234 4.6 32.0 1.0 CA B:GLY229 4.7 27.6 1.0 C B:GLY229 4.7 27.6 1.0 C B:ALA230 4.7 31.5 1.0 CA B:TYR232 4.8 37.5 1.0 CB B:ALA225 4.8 25.4 1.0 CA B:ALA225 4.9 25.9 1.0 CA B:ALA233 4.9 37.4 1.0 C B:GLY227 5.0 35.2 1.0

Iron binding site 2 out of 2 in the Crystal Structure of Lactococcus Lactis Dihydroorotate Dehydrogenase B


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 2 of Crystal Structure of Lactococcus Lactis Dihydroorotate Dehydrogenase B within 5.0Å range: probe atom residue distance (Å) B Occ B:Fe503 b:32.2 occ:1.00 FE2 B:FES503 0.0 32.2 1.0 SG B:CYS249 2.2 34.3 1.0 SG B:CYS234 2.2 32.0 1.0 S1 B:FES503 2.2 31.5 1.0 S2 B:FES503 2.3 32.4 1.0 FE1 B:FES503 2.7 32.0 1.0 CB B:CYS249 3.3 36.0 1.0 CB B:CYS234 3.4 35.7 1.0 N B:CYS234 4.1 38.5 1.0 N B:GLY229 4.3 29.3 1.0 N B:CYS249 4.3 36.7 1.0 SG B:CYS226 4.4 27.4 1.0 CA B:CYS234 4.4 38.2 1.0 N B:GLY227 4.4 32.6 1.0 CA B:CYS249 4.5 36.1 1.0 SG B:CYS231 4.5 33.4 1.0 CA B:GLY229 4.5 27.6 1.0 CA B:GLY227 4.6 34.0 1.0 N B:ALA233 4.6 37.2 1.0 CB B:LYS247 4.7 38.5 1.0 N B:TYR232 4.8 36.9 1.0 C B:GLY227 4.8 35.2 1.0 N B:ILE228 4.9 31.7 1.0

P.Rowland, S.Norager, K.F.Jensen, S.Larsen. Structure of Dihydroorotate Dehydrogenase B: Electron Transfer Between Two Flavin Groups Bridged By An Iron-Sulphur Cluster. Structure Fold.Des. V. 8 1227 2000.
ISSN: ISSN 0969-2126
PubMed: 11188687
DOI: 10.1016/S0969-2126(00)00530-X