Iron in PDB 1f8n: Lipoxygenase-1 (Soybean) at 100K, New Refinement

All present enzymatic activity of Lipoxygenase-1 (Soybean) at 100K, New Refinement:
1.13.11.12;

The structure of Lipoxygenase-1 (Soybean) at 100K, New Refinement, PDB code: 1f8n was solved by D.R.Tomchick, W.Minor, T.Holman, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	20.00 / 1.40
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	94.900, 94.000, 49.900, 90.00, 90.10, 90.00
R / Rfree (%)	19.8 / 21.2

The binding sites of Iron atom in the Lipoxygenase-1 (Soybean) at 100K, New Refinement (pdb code 1f8n). This binding sites where shown within 5.0 Angstroms radius around Iron atom.
In total only one binding site of Iron was determined in the Lipoxygenase-1 (Soybean) at 100K, New Refinement, PDB code: 1f8n:

Iron binding site 1 out of 1 in the Lipoxygenase-1 (Soybean) at 100K, New Refinement


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 1 of Lipoxygenase-1 (Soybean) at 100K, New Refinement within 5.0Å range: probe atom residue distance (Å) B Occ A:Fe840 b:20.7 occ:1.00 O A:HOH841 2.1 21.5 1.0 NE2 A:HIS499 2.2 17.5 0.6 NE2 A:HIS499 2.2 19.6 0.4 OXT A:ILE839 2.3 19.4 1.0 NE2 A:HIS690 2.3 13.6 1.0 NE2 A:HIS504 2.3 18.0 1.0 OD1 A:ASN694 2.9 18.9 1.0 CE1 A:HIS499 3.0 15.7 0.6 CE1 A:HIS499 3.1 17.9 0.4 CE1 A:HIS504 3.2 17.7 1.0 C A:ILE839 3.3 21.2 1.0 CD2 A:HIS690 3.3 12.2 1.0 CE1 A:HIS690 3.3 14.2 1.0 CD2 A:HIS499 3.3 17.9 0.6 CD2 A:HIS499 3.3 19.6 0.4 CD2 A:HIS504 3.4 17.6 1.0 O A:ILE839 3.5 20.4 1.0 CG A:ASN694 3.6 13.5 1.0 CB A:ASN694 4.1 11.8 1.0 ND1 A:HIS499 4.2 18.7 0.6 ND1 A:HIS499 4.3 20.5 0.4 ND1 A:HIS504 4.4 17.6 1.0 O A:HOH1626 4.4 41.0 1.0 CG A:HIS499 4.4 14.9 0.6 ND1 A:HIS690 4.4 13.6 1.0 CG A:HIS499 4.4 18.0 0.4 CG A:HIS690 4.4 13.4 1.0 ND2 A:ASN694 4.5 12.1 1.0 CG A:HIS504 4.5 15.4 1.0 CG2 A:ILE837 4.5 15.7 1.0 CA A:ILE839 4.7 16.8 1.0 N A:ILE839 4.9 17.4 1.0

D.R.Tomchick, P.Phan, M.Cymborowski, W.Minor, T.R.Holman. Structural and Functional Characterization of Second-Coordination Sphere Mutants of Soybean Lipoxygenase-1. Biochemistry V. 40 7509 2001.
ISSN: ISSN 0006-2960
PubMed: 11412104
DOI: 10.1021/BI002893D