Iron in PDB 1fgo: Lipoxygenase-1 (Soybean) at 100K, Q495A Mutant

All present enzymatic activity of Lipoxygenase-1 (Soybean) at 100K, Q495A Mutant:
1.13.11.12;

The structure of Lipoxygenase-1 (Soybean) at 100K, Q495A Mutant, PDB code: 1fgo was solved by D.R.Tomchick, W.Minor, T.Holman, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	20.00 / 1.62
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	94.210, 92.780, 49.450, 90.00, 90.46, 90.00
R / Rfree (%)	18.9 / 22.4

The binding sites of Iron atom in the Lipoxygenase-1 (Soybean) at 100K, Q495A Mutant (pdb code 1fgo). This binding sites where shown within 5.0 Angstroms radius around Iron atom.
In total only one binding site of Iron was determined in the Lipoxygenase-1 (Soybean) at 100K, Q495A Mutant, PDB code: 1fgo:

Iron binding site 1 out of 1 in the Lipoxygenase-1 (Soybean) at 100K, Q495A Mutant


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 1 of Lipoxygenase-1 (Soybean) at 100K, Q495A Mutant within 5.0Å range: probe atom residue distance (Å) B Occ A:Fe840 b:15.6 occ:1.00 O A:HOH1665 2.1 18.4 1.0 NE2 A:HIS504 2.2 15.6 1.0 NE2 A:HIS690 2.2 12.4 1.0 OXT A:ILE839 2.2 15.3 1.0 NE2 A:HIS499 2.2 17.1 1.0 OD1 A:ASN694 2.9 18.7 1.0 CE1 A:HIS499 3.0 22.1 1.0 CE1 A:HIS504 3.1 15.7 1.0 CE1 A:HIS690 3.1 13.0 1.0 C A:ILE839 3.1 16.9 1.0 CD2 A:HIS690 3.2 14.4 1.0 CD2 A:HIS504 3.2 16.7 1.0 CD2 A:HIS499 3.4 17.1 1.0 O A:ILE839 3.4 14.0 1.0 CG A:ASN694 3.6 16.1 1.0 CB A:ASN694 4.2 10.3 1.0 ND1 A:HIS499 4.2 21.5 1.0 ND1 A:HIS504 4.2 15.2 1.0 ND1 A:HIS690 4.3 12.5 1.0 CG A:HIS690 4.3 12.3 1.0 CG A:HIS504 4.3 14.2 1.0 CG A:HIS499 4.4 15.3 1.0 CG2 A:ILE837 4.5 12.9 1.0 ND2 A:ASN694 4.5 12.0 1.0 CA A:ILE839 4.5 15.0 1.0 N A:ILE839 4.8 14.8 1.0 CG2 A:ILE839 4.9 14.8 1.0

D.R.Tomchick, P.Phan, M.Cymborowski, W.Minor, T.R.Holman. Structural and Functional Characterization of Second-Coordination Sphere Mutants of Soybean Lipoxygenase-1. Biochemistry V. 40 7509 2001.
ISSN: ISSN 0006-2960
PubMed: 11412104
DOI: 10.1021/BI002893D