Iron in PDB 1fgq: Lipoxygenase-1 (Soybean) at 100K, Q495E Mutant

All present enzymatic activity of Lipoxygenase-1 (Soybean) at 100K, Q495E Mutant:
1.13.11.12;

The structure of Lipoxygenase-1 (Soybean) at 100K, Q495E Mutant, PDB code: 1fgq was solved by D.R.Tomchick, W.Minor, T.Holman, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	20.00 / 1.85
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	93.243, 92.551, 49.177, 90.00, 90.37, 90.00
R / Rfree (%)	18.3 / 21.6

The binding sites of Iron atom in the Lipoxygenase-1 (Soybean) at 100K, Q495E Mutant (pdb code 1fgq). This binding sites where shown within 5.0 Angstroms radius around Iron atom.
In total only one binding site of Iron was determined in the Lipoxygenase-1 (Soybean) at 100K, Q495E Mutant, PDB code: 1fgq:

Iron binding site 1 out of 1 in the Lipoxygenase-1 (Soybean) at 100K, Q495E Mutant


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 1 of Lipoxygenase-1 (Soybean) at 100K, Q495E Mutant within 5.0Å range: probe atom residue distance (Å) B Occ A:Fe840 b:28.8 occ:1.00 NE2 A:HIS499 2.1 28.1 1.0 NE2 A:HIS690 2.1 16.0 1.0 NE2 A:HIS504 2.1 21.2 1.0 O A:HOH1472 2.3 26.8 1.0 OXT A:ILE839 2.3 24.3 1.0 CE1 A:HIS499 2.9 28.7 1.0 CE1 A:HIS504 2.9 18.8 1.0 OD1 A:ASN694 3.0 24.2 1.0 CD2 A:HIS690 3.1 18.5 1.0 CE1 A:HIS690 3.1 18.6 1.0 CD2 A:HIS499 3.2 26.6 1.0 C A:ILE839 3.3 25.2 1.0 CD2 A:HIS504 3.3 19.6 1.0 O A:ILE839 3.5 25.1 1.0 CG A:ASN694 3.6 19.8 1.0 ND1 A:HIS499 4.1 29.5 1.0 CB A:ASN694 4.1 17.8 1.0 ND1 A:HIS504 4.1 19.9 1.0 ND1 A:HIS690 4.2 19.6 1.0 CG A:HIS690 4.2 17.9 1.0 CG A:HIS499 4.3 25.7 1.0 CG A:HIS504 4.3 17.9 1.0 CG2 A:ILE837 4.4 19.0 1.0 ND2 A:ASN694 4.4 20.3 1.0 CA A:ILE839 4.6 22.8 1.0 N A:ILE839 4.8 20.8 1.0 OG1 A:THR503 4.9 19.5 1.0

D.R.Tomchick, P.Phan, M.Cymborowski, W.Minor, T.R.Holman. Structural and Functional Characterization of Second-Coordination Sphere Mutants of Soybean Lipoxygenase-1. Biochemistry V. 40 7509 2001.
ISSN: ISSN 0006-2960
PubMed: 11412104
DOI: 10.1021/BI002893D