Iron in PDB 1fgr: Lipoxygenase-1 (Soybean) at 100K, Q697E Mutant

All present enzymatic activity of Lipoxygenase-1 (Soybean) at 100K, Q697E Mutant:
1.13.11.12;

The structure of Lipoxygenase-1 (Soybean) at 100K, Q697E Mutant, PDB code: 1fgr was solved by D.R.Tomchick, W.Minor, T.Holman, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	20.00 / 1.60
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	94.420, 92.830, 49.360, 90.00, 90.08, 90.00
R / Rfree (%)	19.6 / 22.2

The binding sites of Iron atom in the Lipoxygenase-1 (Soybean) at 100K, Q697E Mutant (pdb code 1fgr). This binding sites where shown within 5.0 Angstroms radius around Iron atom.
In total only one binding site of Iron was determined in the Lipoxygenase-1 (Soybean) at 100K, Q697E Mutant, PDB code: 1fgr:

Iron binding site 1 out of 1 in the Lipoxygenase-1 (Soybean) at 100K, Q697E Mutant


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 1 of Lipoxygenase-1 (Soybean) at 100K, Q697E Mutant within 5.0Å range: probe atom residue distance (Å) B Occ A:Fe840 b:31.6 occ:0.63 NE2 A:HIS504 2.1 30.0 1.0 NE2 A:HIS499 2.1 34.2 0.6 NE2 A:HIS690 2.2 23.6 1.0 O A:HOH1429 2.3 38.2 1.0 NE2 A:HIS499 2.4 36.3 0.4 OXT A:ILE839 2.5 35.2 1.0 CE1 A:HIS499 2.9 35.0 0.6 CE1 A:HIS504 2.9 30.2 1.0 CD2 A:HIS690 3.1 24.1 1.0 CE1 A:HIS499 3.2 34.6 0.4 CD2 A:HIS499 3.2 31.5 0.6 CD2 A:HIS504 3.2 28.0 1.0 CE1 A:HIS690 3.3 22.3 1.0 CD2 A:HIS499 3.4 32.9 0.4 C A:ILE839 3.4 34.4 1.0 OD1 A:ASN694 3.4 25.6 1.0 O A:ILE839 3.6 34.3 1.0 CG A:ASN694 3.9 23.2 1.0 ND1 A:HIS499 4.1 34.4 0.6 ND1 A:HIS504 4.1 29.5 1.0 CG2 A:ILE837 4.2 22.7 1.0 CG A:HIS499 4.2 31.9 0.6 CG A:HIS504 4.3 25.9 1.0 ND1 A:HIS499 4.3 34.2 0.4 CG A:HIS690 4.3 22.1 1.0 CB A:ASN694 4.3 19.6 1.0 ND1 A:HIS690 4.4 23.4 1.0 CG A:HIS499 4.4 32.4 0.4 ND2 A:ASN694 4.7 23.8 1.0 CA A:ILE839 4.8 30.3 1.0 OG1 A:THR503 4.8 24.2 1.0

D.R.Tomchick, P.Phan, M.Cymborowski, W.Minor, T.R.Holman. Structural and Functional Characterization of Second-Coordination Sphere Mutants of Soybean Lipoxygenase-1. Biochemistry V. 40 7509 2001.
ISSN: ISSN 0006-2960
PubMed: 11412104
DOI: 10.1021/BI002893D