Iron in PDB 1gzx: Oxy T State Haemoglobin: Oxygen Bound at All Four Haems

The structure of Oxy T State Haemoglobin: Oxygen Bound at All Four Haems, PDB code: 1gzx was solved by M.Paoli, R.Liddington, J.Tame, A.Wilkinson, G.Dodson, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	10.00 / 2.10
Space group	P 21 21 2 A
Cell size a, b, c (Å), α, β, γ (°)	97.050, 99.500, 66.110, 90.00, 90.00, 90.00
R / Rfree (%)	n/a / n/a

The binding sites of Iron atom in the Oxy T State Haemoglobin: Oxygen Bound at All Four Haems (pdb code 1gzx). This binding sites where shown within 5.0 Angstroms radius around Iron atom.
In total 4 binding sites of Iron where determined in the Oxy T State Haemoglobin: Oxygen Bound at All Four Haems, PDB code: 1gzx:
Jump to Iron binding site number: 1; 2; 3; 4;

Iron binding site 1 out of 4 in the Oxy T State Haemoglobin: Oxygen Bound at All Four Haems


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 1 of Oxy T State Haemoglobin: Oxygen Bound at All Four Haems within 5.0Å range: probe atom residue distance (Å) B Occ A:Fe1142 b:27.5 occ:1.00 FE A:HEM1142 0.0 27.5 1.0 O1 A:OXY1143 1.6 27.5 1.0 NB A:HEM1142 2.0 25.8 1.0 ND A:HEM1142 2.0 27.1 1.0 NC A:HEM1142 2.0 27.8 1.0 NA A:HEM1142 2.1 28.0 1.0 NE2 A:HIS87 2.3 25.5 1.0 O2 A:OXY1143 2.8 33.7 1.0 C1B A:HEM1142 3.0 25.0 1.0 C4D A:HEM1142 3.1 28.1 1.0 C4C A:HEM1142 3.1 25.9 1.0 C1D A:HEM1142 3.1 28.2 1.0 C4B A:HEM1142 3.1 26.8 1.0 C1A A:HEM1142 3.1 27.2 1.0 C4A A:HEM1142 3.1 26.7 1.0 C1C A:HEM1142 3.1 26.5 1.0 CE1 A:HIS87 3.2 24.8 1.0 CHD A:HEM1142 3.4 25.7 1.0 CD2 A:HIS87 3.4 26.5 1.0 CHB A:HEM1142 3.4 26.7 1.0 CHC A:HEM1142 3.4 27.0 1.0 CHA A:HEM1142 3.5 27.8 1.0 NE2 A:HIS58 4.2 20.7 1.0 C2A A:HEM1142 4.2 28.6 1.0 C3D A:HEM1142 4.3 28.6 1.0 C2B A:HEM1142 4.3 25.4 1.0 C3B A:HEM1142 4.3 25.4 1.0 C3A A:HEM1142 4.3 27.2 1.0 C2D A:HEM1142 4.3 28.9 1.0 C3C A:HEM1142 4.3 25.6 1.0 C2C A:HEM1142 4.3 24.9 1.0 ND1 A:HIS87 4.3 26.1 1.0 CE1 A:HIS58 4.5 21.7 1.0 CG A:HIS87 4.5 27.2 1.0 CD1 A:LEU91 4.8 26.7 1.0 CG2 A:VAL62 4.9 27.5 1.0

Iron binding site 2 out of 4 in the Oxy T State Haemoglobin: Oxygen Bound at All Four Haems


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 2 of Oxy T State Haemoglobin: Oxygen Bound at All Four Haems within 5.0Å range: probe atom residue distance (Å) B Occ B:Fe1290 b:19.8 occ:1.00 FE B:HEM1290 0.0 19.8 1.0 O2 B:OXY1291 1.7 19.6 0.5 ND B:HEM1290 2.0 19.4 1.0 NB B:HEM1290 2.0 16.4 1.0 NA B:HEM1290 2.0 19.3 1.0 NC B:HEM1290 2.1 17.1 1.0 NE2 B:HIS235 2.2 20.0 1.0 O1 B:OXY1291 2.8 21.9 0.5 CE1 B:HIS235 3.0 18.9 1.0 C4D B:HEM1290 3.0 21.3 1.0 C4B B:HEM1290 3.0 18.5 1.0 C1A B:HEM1290 3.0 19.1 1.0 C4A B:HEM1290 3.1 18.1 1.0 C1D B:HEM1290 3.1 19.5 1.0 C1B B:HEM1290 3.1 19.3 1.0 C1C B:HEM1290 3.1 14.9 1.0 C4C B:HEM1290 3.1 14.9 1.0 CD2 B:HIS235 3.2 19.5 1.0 CHC B:HEM1290 3.4 16.1 1.0 CHA B:HEM1290 3.4 21.1 1.0 CHD B:HEM1290 3.5 15.6 1.0 CHB B:HEM1290 3.5 18.9 1.0 NE2 B:HIS206 4.0 24.1 1.0 ND1 B:HIS235 4.1 21.7 1.0 CG2 B:VAL210 4.2 20.9 1.0 C3D B:HEM1290 4.2 20.7 1.0 C2D B:HEM1290 4.3 19.3 1.0 C3B B:HEM1290 4.3 17.4 1.0 C3A B:HEM1290 4.3 18.3 1.0 C2A B:HEM1290 4.3 18.9 1.0 CG B:HIS235 4.3 20.9 1.0 C2B B:HEM1290 4.3 18.1 1.0 C3C B:HEM1290 4.3 16.7 1.0 C2C B:HEM1290 4.3 15.8 1.0 CE1 B:HIS206 4.7 25.6 1.0

Iron binding site 3 out of 4 in the Oxy T State Haemoglobin: Oxygen Bound at All Four Haems


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 3 of Oxy T State Haemoglobin: Oxygen Bound at All Four Haems within 5.0Å range: probe atom residue distance (Å) B Occ C:Fe1542 b:25.6 occ:1.00 FE C:HEM1542 0.0 25.6 1.0 O1 C:OXY1543 1.8 25.4 1.0 NA C:HEM1542 2.0 25.0 1.0 ND C:HEM1542 2.0 22.4 1.0 NC C:HEM1542 2.0 23.1 1.0 NB C:HEM1542 2.1 23.1 1.0 NE2 C:HIS487 2.4 26.3 1.0 C4D C:HEM1542 3.0 22.1 1.0 C1A C:HEM1542 3.0 25.8 1.0 C1D C:HEM1542 3.0 21.1 1.0 C4A C:HEM1542 3.1 24.8 1.0 C1B C:HEM1542 3.1 22.4 1.0 C4B C:HEM1542 3.1 21.9 1.0 C4C C:HEM1542 3.1 21.1 1.0 C1C C:HEM1542 3.1 21.2 1.0 O2 C:OXY1543 3.1 30.4 1.0 CHA C:HEM1542 3.3 23.4 1.0 CE1 C:HIS487 3.3 25.8 1.0 CD2 C:HIS487 3.3 24.8 1.0 CHD C:HEM1542 3.4 20.4 1.0 CHB C:HEM1542 3.4 23.5 1.0 CHC C:HEM1542 3.5 22.0 1.0 C3D C:HEM1542 4.2 21.0 1.0 C2D C:HEM1542 4.2 21.7 1.0 C2A C:HEM1542 4.2 26.8 1.0 C3A C:HEM1542 4.3 26.2 1.0 C3C C:HEM1542 4.3 19.2 1.0 C2C C:HEM1542 4.3 19.6 1.0 C2B C:HEM1542 4.3 21.4 1.0 C3B C:HEM1542 4.4 21.7 1.0 ND1 C:HIS487 4.4 25.0 1.0 CG C:HIS487 4.5 26.3 1.0 CD1 C:LEU491 4.5 21.0 1.0 NE2 C:HIS458 4.6 21.0 1.0 CE1 C:HIS458 4.7 22.1 1.0

Iron binding site 4 out of 4 in the Oxy T State Haemoglobin: Oxygen Bound at All Four Haems


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 4 of Oxy T State Haemoglobin: Oxygen Bound at All Four Haems within 5.0Å range: probe atom residue distance (Å) B Occ D:Fe1690 b:26.2 occ:1.00 FE D:HEM1690 0.0 26.2 1.0 O2 D:OXY1691 1.8 30.0 1.0 ND D:HEM1690 2.0 27.8 1.0 NB D:HEM1690 2.0 27.5 1.0 NA D:HEM1690 2.0 28.9 1.0 NC D:HEM1690 2.1 27.2 1.0 NE2 D:HIS635 2.2 23.7 1.0 O1 D:OXY1691 3.0 36.5 1.0 C1B D:HEM1690 3.0 27.7 1.0 C1D D:HEM1690 3.0 28.4 1.0 C4D D:HEM1690 3.0 28.3 1.0 C4A D:HEM1690 3.1 28.3 1.0 C1A D:HEM1690 3.1 28.8 1.0 C4C D:HEM1690 3.1 26.4 1.0 C4B D:HEM1690 3.1 27.7 1.0 C1C D:HEM1690 3.1 26.7 1.0 CD2 D:HIS635 3.2 24.3 1.0 CE1 D:HIS635 3.2 23.7 1.0 CHA D:HEM1690 3.4 28.9 1.0 CHD D:HEM1690 3.4 27.5 1.0 CHB D:HEM1690 3.4 28.8 1.0 CHC D:HEM1690 3.6 27.5 1.0 C2D D:HEM1690 4.2 28.5 1.0 C3D D:HEM1690 4.2 29.3 1.0 C2B D:HEM1690 4.2 27.8 1.0 C2A D:HEM1690 4.2 29.8 1.0 C3A D:HEM1690 4.3 29.9 1.0 C3C D:HEM1690 4.3 26.3 1.0 C3B D:HEM1690 4.3 27.6 1.0 ND1 D:HIS635 4.3 21.5 1.0 C2C D:HEM1690 4.3 26.1 1.0 CG D:HIS635 4.4 23.6 1.0 NE2 D:HIS606 4.4 34.5 1.0 CG2 D:VAL610 4.5 24.1 1.0 CE1 D:HIS606 4.7 34.6 1.0

M.Paoli, R.Liddington, J.Tame, A.Wilkinson, G.Dodson. Crystal Structure of T State Haemoglobin with Oxygen Bound at All Four Haems. J.Mol.Biol. V. 256 775 1996.
ISSN: ISSN 0022-2836
PubMed: 8642597
DOI: 10.1006/JMBI.1996.0124