Iron in PDB 1h76: The Crystal Structure of Diferric Porcine Serum Transferrin

The structure of The Crystal Structure of Diferric Porcine Serum Transferrin, PDB code: 1h76 was solved by D.R.Hall, J.M.Hadden, G.A.Leonard, S.Bailey, M.Neu, M.Winn, P.F.Lindley, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	30.00 / 2.15
Space group	C 1 2 1
Cell size a, b, c (Å), α, β, γ (°)	223.770, 44.890, 78.860, 90.00, 105.39, 90.00
R / Rfree (%)	13.6 / 18.2

The binding sites of Iron atom in the The Crystal Structure of Diferric Porcine Serum Transferrin (pdb code 1h76). This binding sites where shown within 5.0 Angstroms radius around Iron atom.
In total 2 binding sites of Iron where determined in the The Crystal Structure of Diferric Porcine Serum Transferrin, PDB code: 1h76:
Jump to Iron binding site number: 1; 2;

Iron binding site 1 out of 2 in the The Crystal Structure of Diferric Porcine Serum Transferrin


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 1 of The Crystal Structure of Diferric Porcine Serum Transferrin within 5.0Å range: probe atom residue distance (Å) B Occ A:Fe702 b:14.1 occ:1.00 OH A:TYR192 1.8 15.2 1.0 OH A:TYR94 2.0 13.0 1.0 OD1 A:ASP62 2.1 12.8 1.0 O2 A:CO3700 2.1 13.9 1.0 O3 A:CO3700 2.2 14.4 1.0 NE2 A:HIS253 2.2 13.9 1.0 C A:CO3700 2.5 14.8 1.0 CZ A:TYR192 3.0 15.2 1.0 CZ A:TYR94 3.0 11.2 1.0 CD2 A:HIS253 3.2 13.6 1.0 CG A:ASP62 3.2 11.2 1.0 CE1 A:HIS253 3.2 12.6 1.0 CE1 A:TYR94 3.6 13.6 1.0 CE1 A:TYR192 3.7 18.1 1.0 CB A:ASP62 3.7 12.5 1.0 O1 A:CO3700 3.8 13.6 1.0 O A:HOH2059 3.8 12.1 1.0 CE2 A:TYR192 3.9 14.3 1.0 CE2 A:TYR94 4.1 14.4 1.0 OD2 A:ASP62 4.2 14.1 1.0 ND1 A:HIS253 4.3 15.8 1.0 CG A:HIS253 4.3 14.3 1.0 NZ A:LYS300 4.4 16.2 1.0 CA A:ASP62 4.5 11.6 1.0 CB A:SER124 4.6 14.4 1.0 NH1 A:ARG123 4.6 18.2 1.0 N A:ALA125 4.8 14.4 1.0 NE A:ARG123 4.8 17.3 1.0 N A:SER124 4.9 13.8 1.0 CD1 A:TYR94 4.9 14.1 1.0 OG A:SER124 5.0 13.6 1.0

Iron binding site 2 out of 2 in the The Crystal Structure of Diferric Porcine Serum Transferrin


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 2 of The Crystal Structure of Diferric Porcine Serum Transferrin within 5.0Å range: probe atom residue distance (Å) B Occ A:Fe703 b:9.0 occ:1.00 OH A:TYR526 1.9 11.0 1.0 OH A:TYR431 1.9 7.3 1.0 OD2 A:ASP396 2.0 8.5 1.0 O3 A:CO3701 2.1 7.6 1.0 O1 A:CO3701 2.1 6.9 1.0 NE2 A:HIS594 2.2 6.2 1.0 C A:CO3701 2.4 8.5 1.0 CZ A:TYR526 3.0 8.3 1.0 CZ A:TYR431 3.0 7.1 1.0 CG A:ASP396 3.1 8.2 1.0 CE1 A:HIS594 3.1 7.0 1.0 CD2 A:HIS594 3.2 8.8 1.0 CE2 A:TYR431 3.6 9.2 1.0 O2 A:CO3701 3.6 9.3 1.0 CE2 A:TYR526 3.7 6.8 1.0 CB A:ASP396 3.9 5.3 1.0 O A:HOH2316 3.9 5.7 1.0 CE1 A:TYR526 4.0 9.7 1.0 CE1 A:TYR431 4.0 7.3 1.0 OD1 A:ASP396 4.0 10.8 1.0 ND1 A:HIS594 4.3 5.9 1.0 CG A:HIS594 4.3 8.6 1.0 NH1 A:ARG641 4.4 16.3 1.0 CB A:THR463 4.4 10.3 1.0 NH1 A:ARG462 4.5 13.8 1.0 CA A:ASP396 4.5 6.7 1.0 N A:ALA464 4.9 9.2 1.0 N A:THR463 4.9 9.7 1.0 OG1 A:THR463 4.9 6.8 1.0 CD2 A:TYR431 4.9 10.0 1.0 NE A:ARG462 4.9 13.2 1.0

D.R.Hall, J.M.Hadden, G.A.Leonard, S.Bailey, M.Neu, M.Winn, P.F.Lindley. The Crystal and Molecular Structures of Diferric Porcine and Rabbit Serum Transferrins at Resolutions of 2.15 and 2.60A, Respectively Acta Crystallogr.,Sect.D V. 58 70 2002.
ISSN: ISSN 0907-4449
PubMed: 11752780
DOI: 10.1107/S0907444901017309