Iron in PDB 1hjg: Alteration of the Co-Substrate Selectivity of Deacetoxycephalosporin C Synthase: the Role of Arginine-258

The structure of Alteration of the Co-Substrate Selectivity of Deacetoxycephalosporin C Synthase: the Role of Arginine-258, PDB code: 1hjg was solved by H.J.Lee, M.D.Lloyd, I.J.Clifton, K.Harlos, A.Dubus, J.E.Baldwin, J.M.Frere, C.J.Schofield, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	19.40 / 1.50
Space group	H 3
Cell size a, b, c (Å), α, β, γ (°)	107.100, 107.100, 70.858, 90.00, 90.00, 120.00
R / Rfree (%)	22.5 / 24.1

The binding sites of Iron atom in the Alteration of the Co-Substrate Selectivity of Deacetoxycephalosporin C Synthase: the Role of Arginine-258 (pdb code 1hjg). This binding sites where shown within 5.0 Angstroms radius around Iron atom.
In total only one binding site of Iron was determined in the Alteration of the Co-Substrate Selectivity of Deacetoxycephalosporin C Synthase: the Role of Arginine-258, PDB code: 1hjg:

Iron binding site 1 out of 1 in the Alteration of the Co-Substrate Selectivity of Deacetoxycephalosporin C Synthase: the Role of Arginine-258


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 1 of Alteration of the Co-Substrate Selectivity of Deacetoxycephalosporin C Synthase: the Role of Arginine-258 within 5.0Å range: probe atom residue distance (Å) B Occ A:Fe1307 b:19.8 occ:1.00 O1 A:KIV1308 2.1 24.6 1.0 OD1 A:ASP185 2.2 15.7 1.0 O3 A:KIV1308 2.2 25.2 1.0 NE2 A:HIS243 2.2 20.7 1.0 NE2 A:HIS183 2.3 21.1 1.0 O A:HOH2129 2.3 23.7 1.0 C1 A:KIV1308 2.8 27.4 1.0 C2 A:KIV1308 2.9 28.1 1.0 CG A:ASP185 3.1 16.6 1.0 CE1 A:HIS243 3.2 20.7 1.0 OD2 A:ASP185 3.2 17.1 1.0 CE1 A:HIS183 3.2 21.4 1.0 CD2 A:HIS243 3.2 21.6 1.0 CD2 A:HIS183 3.3 20.4 1.0 O2 A:KIV1308 4.0 29.3 1.0 CG2 A:ILE305 4.2 20.1 1.0 ND1 A:HIS243 4.4 20.6 1.0 C3 A:KIV1308 4.4 28.9 1.0 ND1 A:HIS183 4.4 21.3 1.0 CG A:HIS243 4.4 21.2 1.0 CG A:HIS183 4.4 21.0 1.0 CB A:ASP185 4.5 14.8 1.0 C4 A:KIV1308 4.9 30.1 1.0 N A:ASP185 4.9 14.6 1.0 CE1 A:PHE264 4.9 19.8 1.0 CA A:ASP185 4.9 13.9 1.0 CD2 A:PHE225 5.0 22.2 1.0

H.J.Lee, M.D.Lloyd, K.Harlos, I.J.Clifton, J.E.Baldwin, C.J.Schofield. Alteration of the 2-Oxoacid Cosubstrate Selectivity in Deacetoxycephalosporin C Synthase: the Role of Arginine-258 J.Biol.Chem. V. 276 18290 2001.
ISSN: ISSN 0021-9258
PubMed: 11279000
DOI: 10.1074/JBC.M100085200