Iron in PDB 1jnq: Lipoxygenase-3 (Soybean) Complex with Epigallocathechin (Egc)

All present enzymatic activity of Lipoxygenase-3 (Soybean) Complex with Epigallocathechin (Egc):
1.13.11.12;

The structure of Lipoxygenase-3 (Soybean) Complex with Epigallocathechin (Egc), PDB code: 1jnq was solved by K.Zhou, E.Skrzypczak-Jankun, J.Jankun, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	8.00 / 2.10
Space group	C 1 2 1
Cell size a, b, c (Å), α, β, γ (°)	112.730, 137.270, 61.880, 90.00, 95.53, 90.00
R / Rfree (%)	19.9 / 29.5

The binding sites of Iron atom in the Lipoxygenase-3 (Soybean) Complex with Epigallocathechin (Egc) (pdb code 1jnq). This binding sites where shown within 5.0 Angstroms radius around Iron atom.
In total only one binding site of Iron was determined in the Lipoxygenase-3 (Soybean) Complex with Epigallocathechin (Egc), PDB code: 1jnq:

Iron binding site 1 out of 1 in the Lipoxygenase-3 (Soybean) Complex with Epigallocathechin (Egc)


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 1 of Lipoxygenase-3 (Soybean) Complex with Epigallocathechin (Egc) within 5.0Å range: probe atom residue distance (Å) B Occ A:Fe858 b:32.1 occ:1.00 OXT A:ILE857 2.1 27.1 1.0 NE2 A:HIS518 2.2 30.6 1.0 NE2 A:HIS709 2.2 19.5 1.0 NE2 A:HIS523 2.2 30.6 1.0 O19 A:EGT871 2.7 50.2 1.0 C A:ILE857 2.9 29.9 1.0 CE1 A:HIS518 3.0 26.8 1.0 O A:ILE857 3.1 35.8 1.0 CE1 A:HIS709 3.1 18.6 1.0 CE1 A:HIS523 3.2 30.8 1.0 C8 A:EGT871 3.3 51.8 1.0 CD2 A:HIS523 3.3 25.6 1.0 CD2 A:HIS709 3.4 9.3 1.0 CD2 A:HIS518 3.4 34.1 1.0 C9 A:EGT871 3.6 50.4 1.0 OD1 A:ASN713 3.8 17.6 1.0 CG A:ASN713 4.0 13.8 1.0 ND1 A:HIS518 4.2 25.5 1.0 ND1 A:HIS709 4.3 13.3 1.0 ND1 A:HIS523 4.3 23.7 1.0 CG2 A:ILE855 4.4 13.5 1.0 CA A:ILE857 4.4 27.9 1.0 C7 A:EGT871 4.4 51.7 1.0 CG A:HIS709 4.5 13.9 1.0 CG A:HIS518 4.5 27.9 1.0 ND2 A:ASN713 4.5 12.6 1.0 CG A:HIS523 4.5 19.9 1.0 CB A:ASN713 4.5 10.4 1.0 C10 A:EGT871 4.7 48.6 1.0 N A:ILE857 4.8 28.6 1.0

E.Skrzypczak-Jankun, K.Zhou, J.Jankun. Inhibition of Lipoxygenase By (-)-Epigallocatechin Gallate: X-Ray Analysis at 2.1 A Reveals Degradation of Egcg and Shows Soybean Lox-3 Complex with Egc Instead. Int.J.Mol.Med. V. 12 415 2003.
ISSN: ISSN 1107-3756
PubMed: 12964012