Iron in PDB 1lfk: Crystal Structure of Oxyb, A Cytochrome P450 Implicated in An Oxidative Phenol Coupling Reaction During Vancomycin Biosynthesis

The structure of Crystal Structure of Oxyb, A Cytochrome P450 Implicated in An Oxidative Phenol Coupling Reaction During Vancomycin Biosynthesis, PDB code: 1lfk was solved by O.Pylypenko, K.Zerbe, F.Vitali, W.Zhang, J.W.Vrijbloed, J.A.Robinson, I.Schlichting, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	28.80 / 1.70
Space group	C 1 2 1
Cell size a, b, c (Å), α, β, γ (°)	100.400, 60.400, 90.300, 90.00, 122.70, 90.00
R / Rfree (%)	20.3 / 23.5

The binding sites of Iron atom in the Crystal Structure of Oxyb, A Cytochrome P450 Implicated in An Oxidative Phenol Coupling Reaction During Vancomycin Biosynthesis (pdb code 1lfk). This binding sites where shown within 5.0 Angstroms radius around Iron atom.
In total only one binding site of Iron was determined in the Crystal Structure of Oxyb, A Cytochrome P450 Implicated in An Oxidative Phenol Coupling Reaction During Vancomycin Biosynthesis, PDB code: 1lfk:

Iron binding site 1 out of 1 in the Crystal Structure of Oxyb, A Cytochrome P450 Implicated in An Oxidative Phenol Coupling Reaction During Vancomycin Biosynthesis


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 1 of Crystal Structure of Oxyb, A Cytochrome P450 Implicated in An Oxidative Phenol Coupling Reaction During Vancomycin Biosynthesis within 5.0Å range: probe atom residue distance (Å) B Occ A:Fe430 b:14.7 occ:1.00 FE A:HEM430 0.0 14.7 1.0 ND A:HEM430 2.0 14.9 1.0 NA A:HEM430 2.0 14.5 1.0 NC A:HEM430 2.0 14.2 1.0 NB A:HEM430 2.0 14.6 1.0 O A:HOH698 2.3 25.1 1.0 SG A:CYS347 2.3 17.0 1.0 C1D A:HEM430 3.0 16.2 1.0 C4D A:HEM430 3.0 16.5 1.0 C4A A:HEM430 3.1 15.0 1.0 C1A A:HEM430 3.1 17.1 1.0 C4C A:HEM430 3.1 15.1 1.0 C1B A:HEM430 3.1 14.3 1.0 C1C A:HEM430 3.1 15.2 1.0 C4B A:HEM430 3.1 13.7 1.0 CB A:CYS347 3.4 13.1 1.0 CHD A:HEM430 3.4 16.2 1.0 CHA A:HEM430 3.4 16.9 1.0 CHB A:HEM430 3.4 14.1 1.0 CHC A:HEM430 3.5 14.4 1.0 CA A:CYS347 4.0 15.2 1.0 C2D A:HEM430 4.3 16.3 1.0 C3D A:HEM430 4.3 17.4 1.0 C2A A:HEM430 4.3 16.0 1.0 C3A A:HEM430 4.3 16.1 1.0 C3C A:HEM430 4.3 15.5 1.0 C2C A:HEM430 4.3 14.8 1.0 C2B A:HEM430 4.3 14.2 1.0 C3B A:HEM430 4.3 13.9 1.0 O A:ALA236 4.4 20.5 1.0 ND2 A:ASN240 4.6 21.9 1.0 C A:CYS347 4.7 13.9 1.0 O A:HOH626 4.7 43.6 1.0 N A:LEU348 4.8 15.4 1.0 N A:GLY349 4.8 16.6 1.0 CB A:ALA236 4.8 20.7 1.0

K.Zerbe, O.Pylypenko, F.Vitali, W.Zhang, S.Rouset, M.Heck, J.W.Vrijbloed, D.Bischoff, B.Bister, R.D.Sussmuth, S.Pelzer, W.Wohlleben, J.A.Robinson, I.Schlichting. Crystal Structure of Oxyb, A Cytochrome P450 Implicated in An Oxidative Phenol Coupling Reaction During Vancomycin Biosynthesis. J.Biol.Chem. V. 277 47476 2002.
ISSN: ISSN 0021-9258
PubMed: 12207020
DOI: 10.1074/JBC.M206342200