Iron in PDB 1lm4: Structure of Peptide Deformylase From Staphylococcus Aureus at 1.45 A

All present enzymatic activity of Structure of Peptide Deformylase From Staphylococcus Aureus at 1.45 A:
3.5.1.88;

The structure of Structure of Peptide Deformylase From Staphylococcus Aureus at 1.45 A, PDB code: 1lm4 was solved by A.Kreusch, G.Spraggon, C.C.Lee, H.Klock, D.Mcmullan, K.Ng, T.Shin, J.Vincent, I.Warner, C.Ericson, S.A.Lesley, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	45.26 / 1.45
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	38.224, 76.703, 112.116, 90.00, 90.00, 90.00
R / Rfree (%)	17 / 20

The binding sites of Iron atom in the Structure of Peptide Deformylase From Staphylococcus Aureus at 1.45 A (pdb code 1lm4). This binding sites where shown within 5.0 Angstroms radius around Iron atom.
In total 2 binding sites of Iron where determined in the Structure of Peptide Deformylase From Staphylococcus Aureus at 1.45 A, PDB code: 1lm4:
Jump to Iron binding site number: 1; 2;

Iron binding site 1 out of 2 in the Structure of Peptide Deformylase From Staphylococcus Aureus at 1.45 A


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 1 of Structure of Peptide Deformylase From Staphylococcus Aureus at 1.45 A within 5.0Å range: probe atom residue distance (Å) B Occ A:Fe603 b:22.8 occ:1.00 N A:GLY-10 2.1 17.3 1.0 NE2 A:HIS158 2.2 16.6 1.0 NE2 A:HIS154 2.2 16.9 1.0 SG A:OCS111 2.2 18.3 1.0 OD3 A:OCS111 2.7 28.2 1.0 OD1 A:OCS111 3.0 35.6 1.0 CD2 A:HIS154 3.0 15.6 1.0 CA A:GLY-10 3.0 18.5 1.0 CE1 A:HIS158 3.1 17.2 1.0 CD2 A:HIS158 3.2 17.2 1.0 C A:GLY-10 3.3 20.2 1.0 CE1 A:HIS154 3.3 18.0 1.0 CB A:OCS111 3.5 17.3 1.0 O A:HOH628 3.5 19.5 1.0 O A:GLY-10 3.7 20.4 1.0 NE2 A:GLN65 3.7 21.0 1.0 N A:SER-9 3.8 19.0 1.0 CA A:OCS111 3.9 16.1 1.0 OE1 A:GLN65 4.0 17.1 1.0 CD A:GLN65 4.1 19.4 1.0 ND1 A:HIS158 4.2 16.8 1.0 CG A:HIS154 4.2 15.9 1.0 OE1 A:GLU155 4.3 19.8 1.0 CG A:HIS158 4.3 16.2 1.0 ND1 A:HIS154 4.3 20.4 1.0 O A:HOH614 4.6 17.8 1.0 N A:LEU112 4.6 17.1 1.0 OE2 A:GLU155 4.7 22.4 1.0 C A:OCS111 4.7 15.4 1.0 CA A:SER-9 4.8 19.4 1.0 O A:GLY110 4.8 20.0 1.0 CD A:GLU155 4.8 20.3 1.0

Iron binding site 2 out of 2 in the Structure of Peptide Deformylase From Staphylococcus Aureus at 1.45 A


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 2 of Structure of Peptide Deformylase From Staphylococcus Aureus at 1.45 A within 5.0Å range: probe atom residue distance (Å) B Occ B:Fe603 b:24.1 occ:1.00 O B:HOH616 2.1 19.3 1.0 NE2 B:HIS158 2.1 17.1 1.0 NE2 B:HIS154 2.2 17.1 1.0 SG B:OCS111 2.3 19.4 1.0 OD1 B:OCS111 2.8 30.8 1.0 CD2 B:HIS154 3.0 15.8 1.0 CE1 B:HIS158 3.0 18.3 1.0 OD3 B:OCS111 3.1 32.4 1.0 CD2 B:HIS158 3.1 17.0 1.0 CE1 B:HIS154 3.3 17.7 1.0 O B:HOH692 3.4 29.4 1.0 O B:HOH606 3.5 17.8 1.0 CB B:OCS111 3.5 17.3 1.0 NE2 B:GLN65 3.6 18.8 1.0 CA B:OCS111 3.9 19.7 1.0 OE1 B:GLN65 3.9 17.4 1.0 CD B:GLN65 3.9 18.5 1.0 OE2 B:GLU155 4.0 21.5 1.0 ND1 B:HIS158 4.1 15.0 1.0 CG B:HIS154 4.2 14.8 1.0 CG B:HIS158 4.2 14.0 1.0 ND1 B:HIS154 4.3 18.4 1.0 O B:HOH615 4.4 17.2 1.0 OE1 B:GLU155 4.5 19.7 1.0 N B:LEU112 4.6 22.4 1.0 CD B:GLU155 4.6 19.0 1.0 O B:GLY110 4.7 23.5 1.0 C B:OCS111 4.7 19.7 1.0 O3 B:GOL601 5.0 33.4 1.0

A.Kreusch, G.Spraggon, C.C.Lee, H.Klock, D.Mcmullan, K.Ng, T.Shin, J.Vincent, I.Warner, C.Ericson, S.A.Lesley. Structure Analysis of Peptide Deformylases From Streptococcus Pneumoniae,Staphylococcus Aureus, Thermotoga Maritima, and Pseudomonas Aeruginosa: Snapshots of the Oxygen Sensitivity of Peptide Deformylase J.Mol.Biol. V. 330 309 2003.
ISSN: ISSN 0022-2836
PubMed: 12823970
DOI: 10.1016/S0022-2836(03)00596-5