Iron in PDB 1p2y: Crystal Structure of Cytochrome P450CAM in Complex with (S)- (-)-Nicotine

All present enzymatic activity of Crystal Structure of Cytochrome P450CAM in Complex with (S)- (-)-Nicotine:
1.14.15.1;

The structure of Crystal Structure of Cytochrome P450CAM in Complex with (S)- (-)-Nicotine, PDB code: 1p2y was solved by M.Strickler, B.M.Goldstein, K.Maxfield, L.Shireman, G.Kim, D.Matteson, J.P.Jones, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	39.52 / 2.30
Space group	P 43 21 2
Cell size a, b, c (Å), α, β, γ (°)	64.050, 64.050, 251.060, 90.00, 90.00, 90.00
R / Rfree (%)	22.3 / 26.3

The binding sites of Iron atom in the Crystal Structure of Cytochrome P450CAM in Complex with (S)- (-)-Nicotine (pdb code 1p2y). This binding sites where shown within 5.0 Angstroms radius around Iron atom.
In total only one binding site of Iron was determined in the Crystal Structure of Cytochrome P450CAM in Complex with (S)- (-)-Nicotine, PDB code: 1p2y:

Iron binding site 1 out of 1 in the Crystal Structure of Cytochrome P450CAM in Complex with (S)- (-)-Nicotine


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 1 of Crystal Structure of Cytochrome P450CAM in Complex with (S)- (-)-Nicotine within 5.0Å range: probe atom residue distance (Å) B Occ A:Fe430 b:13.8 occ:1.00 FE A:HEM430 0.0 13.8 1.0 NA A:HEM430 2.0 13.8 1.0 NC A:HEM430 2.0 13.8 1.0 ND A:HEM430 2.0 13.8 1.0 NB A:HEM430 2.0 13.8 1.0 N1 A:NCT440 2.2 18.0 1.0 SG A:CYS357 2.3 16.4 1.0 C1 A:NCT440 3.0 18.0 1.0 C4A A:HEM430 3.0 13.8 1.0 C1A A:HEM430 3.0 13.8 1.0 C1C A:HEM430 3.0 13.8 1.0 C4D A:HEM430 3.0 13.8 1.0 C4B A:HEM430 3.0 13.8 1.0 C4C A:HEM430 3.0 13.8 1.0 C1D A:HEM430 3.0 13.8 1.0 C1B A:HEM430 3.1 13.8 1.0 C5 A:NCT440 3.2 18.0 1.0 CHC A:HEM430 3.4 13.8 1.0 CHB A:HEM430 3.4 13.8 1.0 CHA A:HEM430 3.4 13.8 1.0 CHD A:HEM430 3.4 13.8 1.0 CB A:CYS357 3.4 16.4 1.0 CA A:CYS357 4.2 16.1 1.0 C3A A:HEM430 4.3 13.8 1.0 C2A A:HEM430 4.3 13.8 1.0 C2C A:HEM430 4.3 13.8 1.0 C3D A:HEM430 4.3 13.8 1.0 C2D A:HEM430 4.3 13.8 1.0 C3C A:HEM430 4.3 13.8 1.0 C3B A:HEM430 4.3 13.8 1.0 C2B A:HEM430 4.3 13.8 1.0 C2 A:NCT440 4.3 18.0 1.0 C4 A:NCT440 4.5 18.0 1.0 N A:GLY359 4.7 23.4 1.0 N A:LEU358 4.8 22.5 1.0 C A:CYS357 4.9 16.1 1.0 C3 A:NCT440 4.9 18.0 1.0

M.Strickler, B.M.Goldstein, K.Maxfield, L.Shireman, G.Kim, D.Matteson, J.P.Jones. Crystallographic Studies on the Complex Behavior of Nicotine Binding to P450CAM (CYP101)(Dagger). Biochemistry V. 42 11943 2003.
ISSN: ISSN 0006-2960
PubMed: 14556625
DOI: 10.1021/BI034833O