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Atomistry » Iron » PDB 1ozr-1pha » 1pgg » |
Iron in PDB 1pgg: Prostaglandin H2 Synthase-1 Complexed with 1-(4-Iodobenzoyl)-5- Methoxy-2-Methylindole-3-Acetic Acid (Iodoindomethacin), Trans ModelEnzymatic activity of Prostaglandin H2 Synthase-1 Complexed with 1-(4-Iodobenzoyl)-5- Methoxy-2-Methylindole-3-Acetic Acid (Iodoindomethacin), Trans Model
All present enzymatic activity of Prostaglandin H2 Synthase-1 Complexed with 1-(4-Iodobenzoyl)-5- Methoxy-2-Methylindole-3-Acetic Acid (Iodoindomethacin), Trans Model:
1.14.99.1; Protein crystallography data
The structure of Prostaglandin H2 Synthase-1 Complexed with 1-(4-Iodobenzoyl)-5- Methoxy-2-Methylindole-3-Acetic Acid (Iodoindomethacin), Trans Model, PDB code: 1pgg
was solved by
P.J.Loll,
D.Picot,
R.M.Garavito,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 1pgg:
The structure of Prostaglandin H2 Synthase-1 Complexed with 1-(4-Iodobenzoyl)-5- Methoxy-2-Methylindole-3-Acetic Acid (Iodoindomethacin), Trans Model also contains other interesting chemical elements:
Iron Binding Sites:
The binding sites of Iron atom in the Prostaglandin H2 Synthase-1 Complexed with 1-(4-Iodobenzoyl)-5- Methoxy-2-Methylindole-3-Acetic Acid (Iodoindomethacin), Trans Model
(pdb code 1pgg). This binding sites where shown within
5.0 Angstroms radius around Iron atom.
In total 2 binding sites of Iron where determined in the Prostaglandin H2 Synthase-1 Complexed with 1-(4-Iodobenzoyl)-5- Methoxy-2-Methylindole-3-Acetic Acid (Iodoindomethacin), Trans Model, PDB code: 1pgg: Jump to Iron binding site number: 1; 2; Iron binding site 1 out of 2 in 1pggGo back to Iron Binding Sites List in 1pgg
Iron binding site 1 out
of 2 in the Prostaglandin H2 Synthase-1 Complexed with 1-(4-Iodobenzoyl)-5- Methoxy-2-Methylindole-3-Acetic Acid (Iodoindomethacin), Trans Model
Mono view Stereo pair view
Iron binding site 2 out of 2 in 1pggGo back to Iron Binding Sites List in 1pgg
Iron binding site 2 out
of 2 in the Prostaglandin H2 Synthase-1 Complexed with 1-(4-Iodobenzoyl)-5- Methoxy-2-Methylindole-3-Acetic Acid (Iodoindomethacin), Trans Model
Mono view Stereo pair view
Reference:
P.J.Loll,
D.Picot,
O.Ekabo,
R.M.Garavito.
Synthesis and Use of Iodinated Nonsteroidal Antiinflammatory Drug Analogs As Crystallographic Probes of the Prostaglandin H2 Synthase Cyclooxygenase Active Site. Biochemistry V. 35 7330 1996.
Page generated: Sat Aug 3 13:04:59 2024
ISSN: ISSN 0006-2960 PubMed: 8652509 DOI: 10.1021/BI952776W |
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