Iron in PDB 1s13: Human Heme Oxygenase Oxidatition of Alpha- and Gamma-Meso- Phenylhemes

All present enzymatic activity of Human Heme Oxygenase Oxidatition of Alpha- and Gamma-Meso- Phenylhemes:
1.14.99.3;

The structure of Human Heme Oxygenase Oxidatition of Alpha- and Gamma-Meso- Phenylhemes, PDB code: 1s13 was solved by J.Wang, F.Niemevz, L.Lad, G.Buldain, T.L.Poulos, P.R.Ortiz Demontellano, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	50.00 / 2.29
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	55.070, 75.750, 107.310, 90.00, 90.00, 90.00
R / Rfree (%)	21 / 25

The binding sites of Iron atom in the Human Heme Oxygenase Oxidatition of Alpha- and Gamma-Meso- Phenylhemes (pdb code 1s13). This binding sites where shown within 5.0 Angstroms radius around Iron atom.
In total 2 binding sites of Iron where determined in the Human Heme Oxygenase Oxidatition of Alpha- and Gamma-Meso- Phenylhemes, PDB code: 1s13:
Jump to Iron binding site number: 1; 2;

Iron binding site 1 out of 2 in the Human Heme Oxygenase Oxidatition of Alpha- and Gamma-Meso- Phenylhemes


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 1 of Human Heme Oxygenase Oxidatition of Alpha- and Gamma-Meso- Phenylhemes within 5.0Å range: probe atom residue distance (Å) B Occ A:Fe300 b:57.8 occ:1.00 FE A:2FH300 0.0 57.8 1.0 NB A:2FH300 2.0 58.6 1.0 NC A:2FH300 2.0 57.9 1.0 NA A:2FH300 2.0 58.2 1.0 ND A:2FH300 2.0 57.6 1.0 NE2 A:HIS25 2.3 52.6 1.0 C4B A:2FH300 3.0 58.6 1.0 C4C A:2FH300 3.1 57.7 1.0 C4A A:2FH300 3.1 58.4 1.0 C1B A:2FH300 3.1 58.9 1.0 CD2 A:HIS25 3.1 52.8 1.0 C1C A:2FH300 3.1 58.1 1.0 C1D A:2FH300 3.1 57.5 1.0 C1A A:2FH300 3.1 58.1 1.0 C4D A:2FH300 3.1 57.4 1.0 CHC A:2FH300 3.4 58.4 1.0 CHD A:2FH300 3.4 57.6 1.0 CE1 A:HIS25 3.4 53.0 1.0 CHB A:2FH300 3.4 58.8 1.0 CHA A:2FH300 3.5 57.9 1.0 C3B A:2FH300 4.3 59.3 1.0 C3C A:2FH300 4.3 57.9 1.0 C3A A:2FH300 4.3 58.6 1.0 C2B A:2FH300 4.3 59.3 1.0 CG A:HIS25 4.3 52.9 1.0 C2C A:2FH300 4.3 58.0 1.0 C2D A:2FH300 4.3 57.3 1.0 C2A A:2FH300 4.3 58.4 1.0 C3D A:2FH300 4.3 57.3 1.0 ND1 A:HIS25 4.4 52.9 1.0 O A:GLY139 4.6 47.6 1.0

Iron binding site 2 out of 2 in the Human Heme Oxygenase Oxidatition of Alpha- and Gamma-Meso- Phenylhemes


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 2 of Human Heme Oxygenase Oxidatition of Alpha- and Gamma-Meso- Phenylhemes within 5.0Å range: probe atom residue distance (Å) B Occ B:Fe300 b:66.1 occ:1.00 FE B:2FH300 0.0 66.1 1.0 NB B:2FH300 2.0 66.4 1.0 NA B:2FH300 2.0 66.5 1.0 NC B:2FH300 2.0 66.0 1.0 ND B:2FH300 2.0 66.3 1.0 NE2 B:HIS25 2.4 79.7 1.0 C4B B:2FH300 3.0 66.5 1.0 C4A B:2FH300 3.1 66.6 1.0 C1B B:2FH300 3.1 66.6 1.0 C4C B:2FH300 3.1 66.0 1.0 C1C B:2FH300 3.1 66.0 1.0 C1A B:2FH300 3.1 66.6 1.0 C1D B:2FH300 3.1 66.1 1.0 C4D B:2FH300 3.1 66.3 1.0 CD2 B:HIS25 3.3 79.8 1.0 CHC B:2FH300 3.4 66.3 1.0 CE1 B:HIS25 3.4 79.7 1.0 CHB B:2FH300 3.4 66.5 1.0 CHD B:2FH300 3.4 66.0 1.0 CHA B:2FH300 3.5 66.8 1.0 C3B B:2FH300 4.3 66.8 1.0 C2B B:2FH300 4.3 66.8 1.0 C3A B:2FH300 4.3 66.7 1.0 C2A B:2FH300 4.3 66.7 1.0 C3C B:2FH300 4.3 66.0 1.0 C2C B:2FH300 4.3 65.8 1.0 C2D B:2FH300 4.4 66.2 1.0 C3D B:2FH300 4.4 66.2 1.0 CG B:HIS25 4.4 79.8 1.0 ND1 B:HIS25 4.4 79.8 1.0 O B:GLY139 4.8 53.5 1.0 CA B:GLY139 4.9 52.6 1.0

J.Wang, F.Niemevz, L.Lad, L.Huang, D.E.Alvarez, G.Buldain, T.L.Poulos, P.R.Ortiz De Montellano. Human Heme Oxygenase Oxidation of 5- and 15-Phenylhemes. J.Biol.Chem. V. 279 42593 2004.
ISSN: ISSN 0021-9258
PubMed: 15297453
DOI: 10.1074/JBC.M406346200