Iron in PDB 1suv: Structure of Human Transferrin Receptor-Transferrin Complex

The binding sites of Iron atom in the Structure of Human Transferrin Receptor-Transferrin Complex (pdb code 1suv). This binding sites where shown within 5.0 Angstroms radius around Iron atom.
In total 4 binding sites of Iron where determined in the Structure of Human Transferrin Receptor-Transferrin Complex, PDB code: 1suv:
Jump to Iron binding site number: 1; 2; 3; 4;

Iron binding site 1 out of 4 in the Structure of Human Transferrin Receptor-Transferrin Complex


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 1 of Structure of Human Transferrin Receptor-Transferrin Complex within 5.0Å range: probe atom residue distance (Å) B Occ C:Fe339 b:20.4 occ:1.00 OH C:TYR188 1.8 18.2 1.0 OH C:TYR95 2.0 20.6 1.0 O2 C:CO3338 2.0 10.5 0.3 OD1 C:ASP63 2.0 19.1 1.0 NE2 C:HIS249 2.0 22.0 1.0 O1 C:CO3338 2.1 13.4 0.7 O2 C:CO3338 2.2 28.7 0.7 O1 C:CO3338 2.4 20.1 0.3 C C:CO3338 2.5 19.4 0.7 C C:CO3338 2.5 19.9 0.3 CZ C:TYR188 2.9 25.2 1.0 CE1 C:HIS249 2.9 21.4 1.0 CZ C:TYR95 3.1 27.2 1.0 CD2 C:HIS249 3.1 22.1 1.0 CG C:ASP63 3.2 21.6 1.0 CE2 C:TYR95 3.6 21.5 1.0 CE1 C:TYR188 3.7 21.8 1.0 CB C:ASP63 3.7 18.7 1.0 CE2 C:TYR188 3.8 22.8 1.0 O3 C:CO3338 3.8 15.8 0.3 O3 C:CO3338 3.8 8.9 0.7 ND1 C:HIS249 4.1 21.7 1.0 CE1 C:TYR95 4.1 25.3 1.0 OD2 C:ASP63 4.2 22.2 1.0 CG C:HIS249 4.2 21.6 1.0 NZ C:LYS296 4.3 23.7 1.0 NH2 C:ARG124 4.3 38.3 0.7 CA C:ASP63 4.5 17.7 1.0 CB C:SER125 4.7 19.0 1.0 NE C:ARG124 4.9 46.0 0.7 N C:ALA126 4.9 20.1 1.0 CD C:LYS296 4.9 24.9 1.0 CD2 C:TYR95 4.9 21.9 1.0 N C:SER125 5.0 19.6 1.0 CD1 C:TYR188 5.0 22.4 1.0 OG C:SER125 5.0 21.4 1.0

Iron binding site 2 out of 4 in the Structure of Human Transferrin Receptor-Transferrin Complex


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 2 of Structure of Human Transferrin Receptor-Transferrin Complex within 5.0Å range: probe atom residue distance (Å) B Occ D:Fe339 b:20.4 occ:1.00 OH D:TYR188 1.8 18.2 1.0 OH D:TYR95 2.0 20.6 1.0 O2 D:CO3338 2.0 10.5 0.3 OD1 D:ASP63 2.0 19.1 1.0 NE2 D:HIS249 2.0 22.0 1.0 O1 D:CO3338 2.1 13.4 0.7 O2 D:CO3338 2.2 28.7 0.7 O1 D:CO3338 2.4 20.1 0.3 C D:CO3338 2.5 19.4 0.7 C D:CO3338 2.5 19.9 0.3 CZ D:TYR188 2.9 25.2 1.0 CE1 D:HIS249 2.9 21.4 1.0 CZ D:TYR95 3.1 27.2 1.0 CD2 D:HIS249 3.1 22.1 1.0 CG D:ASP63 3.2 21.6 1.0 CE2 D:TYR95 3.6 21.5 1.0 CE1 D:TYR188 3.7 21.8 1.0 CB D:ASP63 3.7 18.7 1.0 CE2 D:TYR188 3.8 22.8 1.0 O3 D:CO3338 3.8 15.8 0.3 O3 D:CO3338 3.8 8.9 0.7 ND1 D:HIS249 4.1 21.7 1.0 CE1 D:TYR95 4.1 25.3 1.0 OD2 D:ASP63 4.2 22.2 1.0 CG D:HIS249 4.2 21.6 1.0 NZ D:LYS296 4.3 23.7 1.0 NH2 D:ARG124 4.3 38.3 0.7 CA D:ASP63 4.5 17.7 1.0 CB D:SER125 4.7 19.0 1.0 NE D:ARG124 4.9 46.0 0.7 N D:ALA126 4.9 20.1 1.0 CD D:LYS296 4.9 24.9 1.0 CD2 D:TYR95 4.9 21.9 1.0 N D:SER125 5.0 19.6 1.0 CD1 D:TYR188 5.0 22.4 1.0 OG D:SER125 5.0 21.4 1.0

Iron binding site 3 out of 4 in the Structure of Human Transferrin Receptor-Transferrin Complex


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 3 of Structure of Human Transferrin Receptor-Transferrin Complex within 5.0Å range: probe atom residue distance (Å) B Occ E:Fe703 b:32.8 occ:1.00 OH E:TYR425 1.7 25.4 1.0 OH E:TYR514 1.9 39.6 1.0 O1 E:CO3701 1.9 26.0 1.0 NE2 E:HIS582 2.1 27.8 1.0 O3 E:CO3701 2.2 27.5 1.0 C E:CO3701 2.3 28.3 1.0 OD1 E:ASP392 2.4 46.0 1.0 CZ E:TYR425 2.8 32.0 1.0 CZ E:TYR514 3.0 33.5 1.0 CE1 E:HIS582 3.0 27.7 1.0 CG E:ASP392 3.1 37.2 1.0 CD2 E:HIS582 3.2 27.9 1.0 CE2 E:TYR425 3.5 36.0 1.0 O2 E:CO3701 3.6 28.8 1.0 CE1 E:TYR514 3.6 33.1 1.0 CB E:ASP392 3.7 36.1 1.0 CE1 E:TYR425 3.9 32.9 1.0 OD2 E:ASP392 3.9 38.0 1.0 CE2 E:TYR514 3.9 32.6 1.0 ND1 E:HIS582 4.1 23.4 1.0 NH1 E:ARG629 4.2 40.6 1.0 CG E:HIS582 4.3 29.3 1.0 CA E:ASP392 4.5 36.9 1.0 NH2 E:ARG455 4.6 37.2 1.0 CB E:THR456 4.6 35.1 1.0 OG1 E:THR456 4.6 35.4 1.0 N E:ALA457 4.8 37.4 1.0 CD2 E:TYR425 4.8 38.2 1.0 N E:THR456 4.8 33.7 1.0 NE E:ARG455 4.8 38.1 1.0 CD1 E:TYR514 4.9 32.5 1.0

Iron binding site 4 out of 4 in the Structure of Human Transferrin Receptor-Transferrin Complex


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 4 of Structure of Human Transferrin Receptor-Transferrin Complex within 5.0Å range: probe atom residue distance (Å) B Occ F:Fe703 b:32.8 occ:1.00 OH F:TYR425 1.7 25.4 1.0 OH F:TYR514 1.9 39.6 1.0 O1 F:CO3701 1.9 26.0 1.0 NE2 F:HIS582 2.1 27.8 1.0 O3 F:CO3701 2.2 27.5 1.0 C F:CO3701 2.3 28.3 1.0 OD1 F:ASP392 2.4 46.0 1.0 CZ F:TYR425 2.8 32.0 1.0 CZ F:TYR514 3.0 33.5 1.0 CE1 F:HIS582 3.0 27.7 1.0 CG F:ASP392 3.1 37.2 1.0 CD2 F:HIS582 3.2 27.9 1.0 CE2 F:TYR425 3.5 36.0 1.0 O2 F:CO3701 3.6 28.8 1.0 CE1 F:TYR514 3.6 33.1 1.0 CB F:ASP392 3.7 36.1 1.0 CE1 F:TYR425 3.9 32.9 1.0 OD2 F:ASP392 3.9 38.0 1.0 CE2 F:TYR514 3.9 32.6 1.0 ND1 F:HIS582 4.1 23.4 1.0 NH1 F:ARG629 4.2 40.6 1.0 CG F:HIS582 4.3 29.3 1.0 CA F:ASP392 4.5 36.9 1.0 NH2 F:ARG455 4.6 37.2 1.0 CB F:THR456 4.6 35.1 1.0 OG1 F:THR456 4.6 35.4 1.0 N F:ALA457 4.8 37.4 1.0 CD2 F:TYR425 4.8 38.2 1.0 N F:THR456 4.8 33.7 1.0 NE F:ARG455 4.8 38.1 1.0 CD1 F:TYR514 4.9 32.5 1.0

Y.Cheng, O.Zak, P.Aisen, S.C.Harrison, T.Walz. Structure of the Human Transferrin Receptor-Transferrin Complex Cell(Cambridge,Mass.) V. 116 565 2004.
ISSN: ISSN 0092-8674
PubMed: 14980223
DOI: 10.1016/S0092-8674(04)00130-8