Iron in PDB 1wb7: Iron Superoxide Dismutase (Fe-Sod) From the Hyperthermophile Sulfolobus Solfataricus. Crystal Structure of the Y41F Mutant.

All present enzymatic activity of Iron Superoxide Dismutase (Fe-Sod) From the Hyperthermophile Sulfolobus Solfataricus. Crystal Structure of the Y41F Mutant.:
1.15.1.1;

The structure of Iron Superoxide Dismutase (Fe-Sod) From the Hyperthermophile Sulfolobus Solfataricus. Crystal Structure of the Y41F Mutant., PDB code: 1wb7 was solved by M.A.Gogliettino, F.Tanfani, A.Scire, T.Ursby, B.S.Adinolfi, T.Cacciamani, E.De Vendittis, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	29.07 / 2.24
Space group	C 1 2 1
Cell size a, b, c (Å), α, β, γ (°)	75.188, 121.753, 59.420, 90.00, 128.74, 90.00
R / Rfree (%)	18.1 / 20.9

The binding sites of Iron atom in the Iron Superoxide Dismutase (Fe-Sod) From the Hyperthermophile Sulfolobus Solfataricus. Crystal Structure of the Y41F Mutant. (pdb code 1wb7). This binding sites where shown within 5.0 Angstroms radius around Iron atom.
In total 2 binding sites of Iron where determined in the Iron Superoxide Dismutase (Fe-Sod) From the Hyperthermophile Sulfolobus Solfataricus. Crystal Structure of the Y41F Mutant., PDB code: 1wb7:
Jump to Iron binding site number: 1; 2;

Iron binding site 1 out of 2 in the Iron Superoxide Dismutase (Fe-Sod) From the Hyperthermophile Sulfolobus Solfataricus. Crystal Structure of the Y41F Mutant.


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 1 of Iron Superoxide Dismutase (Fe-Sod) From the Hyperthermophile Sulfolobus Solfataricus. Crystal Structure of the Y41F Mutant. within 5.0Å range: probe atom residue distance (Å) B Occ A:Fe212 b:14.6 occ:1.00 OD2 A:ASP170 1.9 13.8 1.0 NE2 A:HIS84 2.1 11.1 1.0 NE2 A:HIS174 2.1 16.2 1.0 NE2 A:HIS33 2.2 10.3 1.0 O A:HOH2088 2.4 29.1 1.0 CD2 A:HIS84 3.0 11.6 1.0 CG A:ASP170 3.1 14.0 1.0 CD2 A:HIS174 3.1 16.3 1.0 CE1 A:HIS84 3.1 11.9 1.0 CE1 A:HIS33 3.1 8.7 1.0 CD2 A:HIS33 3.2 8.3 1.0 CE1 A:HIS174 3.2 14.5 1.0 OD1 A:ASP170 3.5 16.1 1.0 ND1 A:HIS84 4.1 11.8 1.0 CG A:HIS84 4.2 10.4 1.0 ND1 A:HIS33 4.2 8.7 1.0 CG A:HIS174 4.2 16.1 1.0 ND1 A:HIS174 4.2 16.6 1.0 CG A:HIS33 4.3 9.7 1.0 CB A:ASP170 4.3 12.8 1.0 CH2 A:TRP135 4.4 10.8 1.0 CZ2 A:TRP135 4.5 8.6 1.0 CB A:PHE172 4.5 14.3 1.0 CB A:ALA175 4.8 15.0 1.0

Iron binding site 2 out of 2 in the Iron Superoxide Dismutase (Fe-Sod) From the Hyperthermophile Sulfolobus Solfataricus. Crystal Structure of the Y41F Mutant.


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 2 of Iron Superoxide Dismutase (Fe-Sod) From the Hyperthermophile Sulfolobus Solfataricus. Crystal Structure of the Y41F Mutant. within 5.0Å range: probe atom residue distance (Å) B Occ B:Fe211 b:14.5 occ:1.00 OD2 B:ASP170 1.9 13.7 1.0 NE2 B:HIS174 2.1 16.2 1.0 NE2 B:HIS84 2.1 11.2 1.0 NE2 B:HIS33 2.2 10.3 1.0 O B:HOH2093 2.4 29.1 1.0 CG B:ASP170 3.0 14.0 1.0 CD2 B:HIS174 3.1 16.3 1.0 CD2 B:HIS84 3.1 11.6 1.0 CE1 B:HIS84 3.1 11.8 1.0 CE1 B:HIS33 3.1 8.7 1.0 CE1 B:HIS174 3.2 14.5 1.0 CD2 B:HIS33 3.2 8.3 1.0 OD1 B:ASP170 3.5 16.1 1.0 ND1 B:HIS84 4.2 11.8 1.0 CG B:HIS84 4.2 10.4 1.0 ND1 B:HIS33 4.2 8.7 1.0 CG B:HIS174 4.2 16.1 1.0 ND1 B:HIS174 4.2 16.6 1.0 CG B:HIS33 4.3 9.7 1.0 CB B:ASP170 4.3 12.8 1.0 CH2 B:TRP135 4.4 10.8 1.0 CZ2 B:TRP135 4.5 8.6 1.0 CB B:PHE172 4.5 14.2 1.0 CB B:ALA175 4.8 15.0 1.0

M.A.Gogliettino, F.Tanfani, A.Scire, T.Ursby, B.S.Adinolfi, T.Cacciamani, E.De Vendittis. The Role of TYR41 and HIS155 in the Functional Properties of Superoxide Dismutase From the Archaeon Sulfolobus Solfataricus Biochemistry V. 43 2199 2004.
ISSN: ISSN 0006-2960
PubMed: 14979716
DOI: 10.1021/BI035661Y