Iron in PDB 1xsm: Protein R2 of Ribonucleotide Reductase From Mouse

All present enzymatic activity of Protein R2 of Ribonucleotide Reductase From Mouse:
1.17.4.1;

The structure of Protein R2 of Ribonucleotide Reductase From Mouse, PDB code: 1xsm was solved by B.Kauppi, B.N.Nielsen, S.Ramaswamy, I.Kjoller-Larsen, M.Thelander, L.Thelander, H.Eklund, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	25.00 / 2.30
Space group	C 2 2 21
Cell size a, b, c (Å), α, β, γ (°)	77.078, 108.932, 92.900, 90.00, 90.00, 90.00
R / Rfree (%)	19.1 / 25

The binding sites of Iron atom in the Protein R2 of Ribonucleotide Reductase From Mouse (pdb code 1xsm). This binding sites where shown within 5.0 Angstroms radius around Iron atom.
In total only one binding site of Iron was determined in the Protein R2 of Ribonucleotide Reductase From Mouse, PDB code: 1xsm:

Iron binding site 1 out of 1 in the Protein R2 of Ribonucleotide Reductase From Mouse


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 1 of Protein R2 of Ribonucleotide Reductase From Mouse within 5.0Å range: probe atom residue distance (Å) B Occ A:Fe401 b:42.6 occ:0.35 OE2 A:GLU170 1.8 45.0 1.0 OE1 A:GLU267 2.3 28.3 1.0 OE2 A:GLU233 2.3 26.3 1.0 OE2 A:GLU267 2.4 44.8 1.0 CD A:GLU170 2.5 28.9 1.0 OE1 A:GLU170 2.6 33.0 1.0 CD A:GLU267 2.7 23.2 1.0 ND1 A:HIS270 2.9 7.8 1.0 CD A:GLU233 3.2 21.9 1.0 CE1 A:HIS270 3.5 7.4 1.0 CG A:GLU170 3.7 19.8 1.0 CG A:GLU233 3.9 29.1 1.0 CG1 A:VAL142 3.9 19.3 1.0 NE2 A:GLN166 4.0 14.8 1.0 CG A:HIS270 4.1 7.4 1.0 CG A:GLU267 4.2 20.1 1.0 OE1 A:GLU233 4.2 26.2 1.0 OD1 A:ASP139 4.5 54.5 1.0 ND1 A:HIS173 4.5 7.2 1.0 CB A:HIS270 4.6 6.3 1.0 CB A:VAL142 4.6 22.4 1.0 CE1 A:HIS173 4.7 5.3 1.0 NE2 A:HIS270 4.8 7.2 1.0 CG2 A:VAL142 4.8 19.2 1.0 CG A:GLN166 4.9 16.1 1.0 CD A:GLN166 4.9 16.3 1.0 CB A:GLU170 5.0 9.4 1.0

B.Kauppi, B.B.Nielsen, S.Ramaswamy, I.K.Larsen, M.Thelander, L.Thelander, H.Eklund. The Three-Dimensional Structure of Mammalian Ribonucleotide Reductase Protein R2 Reveals A More-Accessible Iron-Radical Site Than Escherichia Coli R2. J.Mol.Biol. V. 262 706 1996.
ISSN: ISSN 0022-2836
PubMed: 8876648
DOI: 10.1006/JMBI.1996.0546