Iron in PDB 1yvt: The High Salt (Phosphate) Crystal Structure of Co Hemoglobin E (GLU26LYS) at Physiological pH (pH 7.35)

The structure of The High Salt (Phosphate) Crystal Structure of Co Hemoglobin E (GLU26LYS) at Physiological pH (pH 7.35), PDB code: 1yvt was solved by V.N.Malashkevich, T.C.Balazs, S.C.Almo, R.E.Hirsch, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	22.41 / 1.80
Space group	P 41 21 2
Cell size a, b, c (Å), α, β, γ (°)	53.502, 53.502, 191.958, 90.00, 90.00, 90.00
R / Rfree (%)	19.6 / 23.6

The binding sites of Iron atom in the The High Salt (Phosphate) Crystal Structure of Co Hemoglobin E (GLU26LYS) at Physiological pH (pH 7.35) (pdb code 1yvt). This binding sites where shown within 5.0 Angstroms radius around Iron atom.
In total 2 binding sites of Iron where determined in the The High Salt (Phosphate) Crystal Structure of Co Hemoglobin E (GLU26LYS) at Physiological pH (pH 7.35), PDB code: 1yvt:
Jump to Iron binding site number: 1; 2;

Iron binding site 1 out of 2 in the The High Salt (Phosphate) Crystal Structure of Co Hemoglobin E (GLU26LYS) at Physiological pH (pH 7.35)


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 1 of The High Salt (Phosphate) Crystal Structure of Co Hemoglobin E (GLU26LYS) at Physiological pH (pH 7.35) within 5.0Å range: probe atom residue distance (Å) B Occ A:Fe401 b:22.8 occ:1.00 FE A:HEM401 0.0 22.8 1.0 C A:CMO501 1.9 20.2 1.0 NA A:HEM401 2.0 23.1 1.0 NC A:HEM401 2.1 22.4 1.0 NB A:HEM401 2.1 18.5 1.0 ND A:HEM401 2.1 21.6 1.0 NE2 A:HIS87 2.1 19.7 1.0 O A:CMO501 3.0 22.4 1.0 CD2 A:HIS87 3.0 22.2 1.0 C1C A:HEM401 3.1 19.6 1.0 C4A A:HEM401 3.1 19.9 1.0 C4B A:HEM401 3.1 19.4 1.0 C1A A:HEM401 3.1 21.5 1.0 C1B A:HEM401 3.1 21.0 1.0 C4C A:HEM401 3.1 20.3 1.0 C4D A:HEM401 3.1 24.6 1.0 C1D A:HEM401 3.1 21.3 1.0 CE1 A:HIS87 3.1 20.2 1.0 CHC A:HEM401 3.4 20.3 1.0 CHB A:HEM401 3.4 21.8 1.0 CHA A:HEM401 3.5 21.7 1.0 CHD A:HEM401 3.5 19.4 1.0 CG A:HIS87 4.2 21.2 1.0 ND1 A:HIS87 4.2 22.0 1.0 C3C A:HEM401 4.3 20.5 1.0 C2C A:HEM401 4.3 21.1 1.0 C3A A:HEM401 4.3 22.4 1.0 C3B A:HEM401 4.3 20.5 1.0 C2A A:HEM401 4.3 23.7 1.0 C2B A:HEM401 4.3 20.6 1.0 C3D A:HEM401 4.4 24.2 1.0 C2D A:HEM401 4.4 22.6 1.0 NE2 A:HIS58 4.4 23.7 1.0 CG2 A:VAL62 4.9 20.3 1.0

Iron binding site 2 out of 2 in the The High Salt (Phosphate) Crystal Structure of Co Hemoglobin E (GLU26LYS) at Physiological pH (pH 7.35)


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 2 of The High Salt (Phosphate) Crystal Structure of Co Hemoglobin E (GLU26LYS) at Physiological pH (pH 7.35) within 5.0Å range: probe atom residue distance (Å) B Occ B:Fe402 b:28.3 occ:1.00 FE B:HEM402 0.0 28.3 1.0 C B:CMO502 1.8 26.8 1.0 ND B:HEM402 2.0 28.1 1.0 NA B:HEM402 2.1 24.4 1.0 NB B:HEM402 2.1 28.4 1.0 NC B:HEM402 2.1 24.9 1.0 NE2 B:HIS92 2.1 28.5 1.0 O B:CMO502 2.9 23.8 1.0 C1A B:HEM402 3.0 27.0 1.0 C4D B:HEM402 3.1 28.2 1.0 C1D B:HEM402 3.1 26.3 1.0 C4A B:HEM402 3.1 26.5 1.0 C4B B:HEM402 3.1 28.1 1.0 CD2 B:HIS92 3.1 30.1 1.0 C1B B:HEM402 3.1 25.1 1.0 CE1 B:HIS92 3.1 29.1 1.0 C4C B:HEM402 3.1 29.0 1.0 C1C B:HEM402 3.1 26.6 1.0 CHA B:HEM402 3.4 25.9 1.0 CHC B:HEM402 3.4 26.6 1.0 CHD B:HEM402 3.5 25.5 1.0 CHB B:HEM402 3.5 23.7 1.0 ND1 B:HIS92 4.2 27.9 1.0 CG B:HIS92 4.3 26.8 1.0 C2A B:HEM402 4.3 27.0 1.0 C3D B:HEM402 4.3 28.0 1.0 C2D B:HEM402 4.3 29.1 1.0 C3B B:HEM402 4.3 29.0 1.0 C3A B:HEM402 4.3 22.7 1.0 C2B B:HEM402 4.3 28.8 1.0 C2C B:HEM402 4.4 25.9 1.0 C3C B:HEM402 4.4 25.2 1.0 NE2 B:HIS63 4.5 31.4 1.0 CG2 B:VAL67 4.8 27.5 1.0

V.N.Malashkevich, T.C.Balazs, S.C.Almo, R.E.Hirsch. The High Salt (Phosphate) Crystal Structure of Co Hemoglobin E (GLU26LYS) at Physiological pH (pH 7.35) To Be Published.