Iron in PDB 1zz7: Crystal Structure of Feii Hppe in Complex with Substrate Form 1

The structure of Crystal Structure of Feii Hppe in Complex with Substrate Form 1, PDB code: 1zz7 was solved by L.J.Higgins, F.Yan, P.Liu, H.W.Liu, C.L.Drennan, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	29.03 / 2.10
Space group	P 65 2 2
Cell size a, b, c (Å), α, β, γ (°)	86.560, 86.560, 220.360, 90.00, 90.00, 120.00
R / Rfree (%)	24.4 / 26.6

The binding sites of Iron atom in the Crystal Structure of Feii Hppe in Complex with Substrate Form 1 (pdb code 1zz7). This binding sites where shown within 5.0 Angstroms radius around Iron atom.
In total 2 binding sites of Iron where determined in the Crystal Structure of Feii Hppe in Complex with Substrate Form 1, PDB code: 1zz7:
Jump to Iron binding site number: 1; 2;

Iron binding site 1 out of 2 in the Crystal Structure of Feii Hppe in Complex with Substrate Form 1


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 1 of Crystal Structure of Feii Hppe in Complex with Substrate Form 1 within 5.0Å range: probe atom residue distance (Å) B Occ A:Fe199 b:46.1 occ:1.00 NE2 A:HIS138 1.8 42.2 1.0 O14 A:S0H1002 2.1 69.4 1.0 OE2 A:GLU142 2.2 40.7 1.0 O A:HOH1006 2.2 33.0 1.0 NE2 A:HIS180 2.2 32.9 1.0 O A:HOH1003 2.6 35.3 1.0 CD2 A:HIS138 2.7 42.1 1.0 CE1 A:HIS180 2.8 33.4 1.0 CE1 A:HIS138 2.8 43.4 1.0 CD A:GLU142 3.0 38.8 1.0 OE1 A:GLU142 3.0 40.3 1.0 CD2 A:HIS180 3.4 32.4 1.0 P1 A:S0H1002 3.6 69.7 1.0 ND2 A:ASN135 3.6 48.0 1.0 CG A:HIS138 3.8 43.3 1.0 ND1 A:HIS138 3.9 44.2 1.0 O15 A:S0H1002 3.9 69.4 1.0 ND1 A:HIS180 4.0 32.7 1.0 O13 A:S0H1002 4.3 69.1 1.0 CG A:HIS180 4.4 33.3 1.0 OD1 A:ASN197 4.4 43.3 1.0 CG A:GLU142 4.4 37.9 1.0 ND2 A:ASN197 4.5 42.7 1.0 C2 A:S0H1002 4.8 68.6 1.0 CG A:ASN197 4.9 40.2 1.0 CB A:GLU142 4.9 34.1 1.0 CG A:ASN135 4.9 49.9 1.0

Iron binding site 2 out of 2 in the Crystal Structure of Feii Hppe in Complex with Substrate Form 1


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 2 of Crystal Structure of Feii Hppe in Complex with Substrate Form 1 within 5.0Å range: probe atom residue distance (Å) B Occ B:Fe199 b:46.3 occ:1.00 NE2 B:HIS138 1.7 46.3 1.0 O6 B:S0H1001 2.0 52.3 1.0 OE1 B:GLU142 2.1 34.2 1.0 O15 B:S0H1001 2.1 60.5 1.0 NE2 B:HIS180 2.3 29.8 1.0 CE1 B:HIS138 2.6 46.5 1.0 CD2 B:HIS138 2.9 45.6 1.0 CE1 B:HIS180 3.0 30.4 1.0 CD B:GLU142 3.1 33.9 1.0 C3 B:S0H1001 3.3 55.5 1.0 P1 B:S0H1001 3.4 60.5 1.0 OE2 B:GLU142 3.4 37.2 1.0 CD2 B:HIS180 3.4 30.1 1.0 C2 B:S0H1001 3.7 58.4 1.0 ND1 B:HIS138 3.7 46.4 1.0 O B:HOH1004 3.7 41.2 1.0 CG B:HIS138 3.9 46.2 1.0 C1 B:S0H1001 4.0 56.1 1.0 ND1 B:HIS180 4.2 28.7 1.0 O14 B:S0H1001 4.2 61.6 1.0 O13 B:S0H1001 4.3 61.3 1.0 CG B:GLU142 4.4 32.0 1.0 CG B:HIS180 4.4 31.2 1.0 OD1 B:ASN197 4.5 40.3 1.0 ND2 B:ASN197 4.8 38.3 1.0 CB B:GLU142 4.9 28.6 1.0

L.J.Higgins, F.Yan, P.Liu, H.W.Liu, C.L.Drennan. Structural Insight Into Antibiotic Fosfomycin Biosynthesis By A Mononuclear Iron Enzyme Nature V. 437 838 2005.
ISSN: ISSN 0028-0836
PubMed: 16015285
DOI: 10.1038/NATURE03924