Iron in PDB 2bs2: Quinol:Fumarate Reductase From Wolinella Succinogenes

All present enzymatic activity of Quinol:Fumarate Reductase From Wolinella Succinogenes:
1.3.99.1;

The structure of Quinol:Fumarate Reductase From Wolinella Succinogenes, PDB code: 2bs2 was solved by C.R.D.Lancaster, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	28.70 / 1.78
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	85.104, 188.766, 117.817, 90.00, 104.47, 90.00
R / Rfree (%)	22.9 / 23.7

The structure of Quinol:Fumarate Reductase From Wolinella Succinogenes also contains other interesting chemical elements:

Sodium

(Na)

2 atoms

Pages:

>>> Page 1 <<< Page 2, Binding sites: 11 - 20; Page 3, Binding sites: 21 - 22;

Binding sites:

The binding sites of Iron atom in the Quinol:Fumarate Reductase From Wolinella Succinogenes (pdb code 2bs2). This binding sites where shown within 5.0 Angstroms radius around Iron atom.
In total 22 binding sites of Iron where determined in the Quinol:Fumarate Reductase From Wolinella Succinogenes, PDB code: 2bs2:
Jump to Iron binding site number: 1; 2; 3; 4; 5; 6; 7; 8; 9; 10;

Iron binding site 1 out of 22 in the Quinol:Fumarate Reductase From Wolinella Succinogenes


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 1 of Quinol:Fumarate Reductase From Wolinella Succinogenes within 5.0Å range: probe atom residue distance (Å) B Occ B:Fe1240 b:22.8 occ:1.00 FE1 B:FES1240 0.0 22.8 1.0 SG B:CYS65 2.1 23.7 1.0 S1 B:FES1240 2.2 23.6 1.0 SG B:CYS77 2.2 26.8 1.0 S2 B:FES1240 2.2 24.1 1.0 FE2 B:FES1240 2.7 22.7 1.0 CB B:CYS77 3.3 26.8 1.0 CB B:CYS65 3.4 21.7 1.0 N B:CYS65 3.9 22.0 1.0 N B:GLY60 4.2 26.1 1.0 SG B:CYS57 4.2 22.9 1.0 N B:CYS77 4.3 26.0 1.0 CA B:CYS65 4.3 22.6 1.0 CA B:CYS77 4.4 28.9 1.0 CA B:GLY60 4.5 25.4 1.0 N B:ARG58 4.5 25.1 1.0 CD1 B:PHE55 4.6 24.2 1.0 CA B:ARG58 4.6 25.6 1.0 SG B:CYS62 4.7 23.1 1.0 CB B:LEU75 4.7 26.3 1.0 N B:SER64 4.7 20.0 1.0 CD2 B:LEU75 4.8 26.7 1.0 N B:ALA59 4.8 26.1 1.0 CE1 B:PHE55 4.9 22.2 1.0 C B:ARG58 5.0 27.2 1.0

Iron binding site 2 out of 22 in the Quinol:Fumarate Reductase From Wolinella Succinogenes


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 2 of Quinol:Fumarate Reductase From Wolinella Succinogenes within 5.0Å range: probe atom residue distance (Å) B Occ B:Fe1240 b:22.7 occ:1.00 FE2 B:FES1240 0.0 22.7 1.0 S1 B:FES1240 2.2 23.6 1.0 SG B:CYS62 2.2 23.1 1.0 S2 B:FES1240 2.2 24.1 1.0 SG B:CYS57 2.2 22.9 1.0 FE1 B:FES1240 2.7 22.8 1.0 CB B:CYS62 3.4 24.1 1.0 CB B:CYS57 3.5 22.1 1.0 N B:CYS62 3.6 25.9 1.0 N B:CYS57 3.6 22.6 1.0 N B:ARG58 3.8 25.1 1.0 N B:GLY63 3.8 22.4 1.0 CA B:CYS62 3.9 24.4 1.0 CA B:CYS57 4.0 22.9 1.0 N B:SER64 4.0 20.0 1.0 C B:CYS62 4.2 23.0 1.0 SG B:CYS77 4.3 26.8 1.0 C B:CYS57 4.3 24.7 1.0 CB B:SER64 4.3 22.9 1.0 N B:GLY60 4.3 26.1 1.0 N B:ILE61 4.4 25.1 1.0 SG B:CYS65 4.6 23.7 1.0 N B:VAL56 4.6 22.3 1.0 N B:ALA59 4.6 26.1 1.0 C B:VAL56 4.7 22.3 1.0 CA B:ARG58 4.7 25.6 1.0 CA B:SER64 4.7 21.3 1.0 CA B:GLY60 4.7 25.4 1.0 C B:ILE61 4.8 26.5 1.0 CA B:GLY63 4.8 21.6 1.0 N B:CYS65 4.8 22.0 1.0 CB B:VAL56 4.8 22.4 1.0 C B:GLY63 4.9 22.8 1.0 C B:GLY60 4.9 25.8 1.0 CA B:VAL56 4.9 21.2 1.0

Iron binding site 3 out of 22 in the Quinol:Fumarate Reductase From Wolinella Succinogenes


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 3 of Quinol:Fumarate Reductase From Wolinella Succinogenes within 5.0Å range: probe atom residue distance (Å) B Occ B:Fe1241 b:25.7 occ:1.00 FE1 B:F3S1241 0.0 25.7 1.0 SG B:CYS161 2.2 24.6 1.0 S1 B:F3S1241 2.2 27.0 1.0 S2 B:F3S1241 2.3 25.2 1.0 S3 B:F3S1241 2.3 24.7 1.0 FE3 B:F3S1241 2.7 24.7 1.0 FE4 B:F3S1241 2.8 25.5 1.0 CB B:CYS161 3.4 25.4 1.0 S4 B:F3S1241 3.8 26.8 1.0 CA B:CYS161 4.1 25.6 1.0 CE2 B:PHE170 4.1 25.9 1.0 O B:HOH2104 4.1 21.8 1.0 OG1 B:THR163 4.3 25.7 1.0 CB B:THR163 4.5 25.5 1.0 CB B:LEU211 4.6 25.7 1.0 CD1 B:LEU211 4.7 25.2 1.0 CZ B:PHE170 4.7 25.7 1.0 SG B:CYS214 4.8 23.1 1.0 SG B:CYS208 4.8 24.6 1.0 CG B:LEU211 4.8 25.6 1.0 C B:CYS161 4.8 25.8 1.0 N B:LEU211 4.9 27.9 1.0 N B:THR163 5.0 24.9 1.0

Iron binding site 4 out of 22 in the Quinol:Fumarate Reductase From Wolinella Succinogenes


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 4 of Quinol:Fumarate Reductase From Wolinella Succinogenes within 5.0Å range: probe atom residue distance (Å) B Occ B:Fe1241 b:24.7 occ:1.00 FE3 B:F3S1241 0.0 24.7 1.0 SG B:CYS208 2.1 24.6 1.0 S1 B:F3S1241 2.3 27.0 1.0 S4 B:F3S1241 2.3 26.8 1.0 S3 B:F3S1241 2.3 24.7 1.0 FE1 B:F3S1241 2.7 25.7 1.0 FE4 B:F3S1241 2.8 25.5 1.0 CB B:CYS208 3.5 25.9 1.0 N B:THR210 3.8 27.5 1.0 CA B:CYS208 3.9 26.4 1.0 S2 B:F3S1241 4.0 25.2 1.0 N B:MET209 4.0 26.7 1.0 CA B:THR210 4.2 26.7 1.0 N B:LEU211 4.3 27.9 1.0 C B:CYS208 4.3 26.8 1.0 O B:HOH2142 4.4 25.9 1.0 CZ B:PHE170 4.4 25.7 1.0 CE2 B:PHE170 4.6 25.9 1.0 SG B:CYS161 4.7 24.6 1.0 SG B:CYS214 4.7 23.1 1.0 C B:THR210 4.8 28.0 1.0 C B:MET209 4.8 27.3 1.0 CD1 B:ILE228 4.8 28.6 1.0 N B:LEU212 5.0 26.6 1.0

Iron binding site 5 out of 22 in the Quinol:Fumarate Reductase From Wolinella Succinogenes


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 5 of Quinol:Fumarate Reductase From Wolinella Succinogenes within 5.0Å range: probe atom residue distance (Å) B Occ B:Fe1241 b:25.5 occ:1.00 FE4 B:F3S1241 0.0 25.5 1.0 SG B:CYS214 2.1 23.1 1.0 S4 B:F3S1241 2.2 26.8 1.0 S3 B:F3S1241 2.2 24.7 1.0 S2 B:F3S1241 2.3 25.2 1.0 FE1 B:F3S1241 2.8 25.7 1.0 FE3 B:F3S1241 2.8 24.7 1.0 CB B:CYS214 3.2 23.2 1.0 S1 B:F3S1241 3.9 27.0 1.0 N B:CYS214 3.9 24.6 1.0 N B:LEU212 4.1 26.6 1.0 CA B:CYS214 4.2 23.9 1.0 CA B:LEU212 4.2 27.5 1.0 CB B:ALA173 4.3 23.9 1.0 CD1 B:ILE228 4.5 28.6 1.0 N B:ALA213 4.5 26.6 1.0 C B:LEU212 4.6 27.1 1.0 SG B:CYS208 4.6 24.6 1.0 SG B:CYS161 4.7 24.6 1.0 N B:LEU211 4.9 27.9 1.0 O B:HOH2104 4.9 21.8 1.0 N B:HIS215 5.0 26.0 1.0

Iron binding site 6 out of 22 in the Quinol:Fumarate Reductase From Wolinella Succinogenes


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 6 of Quinol:Fumarate Reductase From Wolinella Succinogenes within 5.0Å range: probe atom residue distance (Å) B Occ B:Fe1242 b:25.2 occ:1.00 FE1 B:SF41242 0.0 25.2 1.0 SG B:CYS157 2.1 24.5 1.0 S2 B:SF41242 2.3 24.6 1.0 S3 B:SF41242 2.3 24.0 1.0 S4 B:SF41242 2.3 22.2 1.0 FE4 B:SF41242 2.7 25.0 1.0 FE3 B:SF41242 2.8 25.2 1.0 FE2 B:SF41242 2.8 24.5 1.0 CB B:CYS157 3.2 23.9 1.0 S1 B:SF41242 3.9 24.4 1.0 N B:CYS157 3.9 22.7 1.0 CA B:CYS157 4.2 24.3 1.0 CB B:ALA174 4.2 24.6 1.0 SG B:CYS151 4.6 24.0 1.0 SG B:CYS154 4.6 26.1 1.0 SG B:CYS218 4.7 27.2 1.0 CA B:ALA174 4.7 24.3 1.0 N B:ALA174 4.8 24.9 1.0 N B:CYS156 4.9 20.9 1.0 N B:GLY155 5.0 22.0 1.0

Iron binding site 7 out of 22 in the Quinol:Fumarate Reductase From Wolinella Succinogenes


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 7 of Quinol:Fumarate Reductase From Wolinella Succinogenes within 5.0Å range: probe atom residue distance (Å) B Occ B:Fe1242 b:24.5 occ:1.00 FE2 B:SF41242 0.0 24.5 1.0 SG B:CYS154 2.2 26.1 1.0 S3 B:SF41242 2.3 24.0 1.0 S4 B:SF41242 2.3 22.2 1.0 S1 B:SF41242 2.3 24.4 1.0 FE3 B:SF41242 2.7 25.2 1.0 FE4 B:SF41242 2.8 25.0 1.0 FE1 B:SF41242 2.8 25.2 1.0 N B:CYS154 3.6 21.7 1.0 CB B:CYS154 3.6 20.8 1.0 S2 B:SF41242 3.9 24.6 1.0 N B:GLY155 4.0 22.0 1.0 CA B:CYS154 4.0 21.7 1.0 CD B:PRO219 4.3 27.3 1.0 N B:CYS156 4.3 20.9 1.0 C B:CYS154 4.4 21.0 1.0 N B:GLU153 4.5 21.9 1.0 CG1 B:ILE152 4.6 21.2 1.0 SG B:CYS151 4.6 24.0 1.0 C B:GLU153 4.6 22.6 1.0 CG B:PRO219 4.6 31.2 1.0 SG B:CYS218 4.6 27.2 1.0 SG B:CYS157 4.6 24.5 1.0 CA B:GLU153 4.8 22.9 1.0 CB B:CYS156 4.8 23.4 1.0 N B:CYS157 4.8 22.7 1.0 N B:ILE152 4.9 23.3 1.0 CA B:GLY155 5.0 22.3 1.0

Iron binding site 8 out of 22 in the Quinol:Fumarate Reductase From Wolinella Succinogenes


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 8 of Quinol:Fumarate Reductase From Wolinella Succinogenes within 5.0Å range: probe atom residue distance (Å) B Occ B:Fe1242 b:25.2 occ:1.00 FE3 B:SF41242 0.0 25.2 1.0 SG B:CYS151 2.2 24.0 1.0 S1 B:SF41242 2.2 24.4 1.0 S4 B:SF41242 2.2 22.2 1.0 S2 B:SF41242 2.2 24.6 1.0 FE2 B:SF41242 2.7 24.5 1.0 FE1 B:SF41242 2.8 25.2 1.0 FE4 B:SF41242 2.8 25.0 1.0 CB B:CYS151 3.3 23.0 1.0 CA B:CYS151 3.7 22.6 1.0 S3 B:SF41242 3.9 24.0 1.0 N B:ILE152 3.9 23.3 1.0 N B:GLU153 4.0 21.9 1.0 C B:CYS151 4.2 23.7 1.0 CA B:GLU153 4.5 22.9 1.0 CB B:ALA174 4.7 24.6 1.0 SG B:CYS157 4.7 24.5 1.0 N B:CYS154 4.7 21.7 1.0 SG B:CYS218 4.8 27.2 1.0 CD2 B:LEU222 4.8 30.4 1.0 O B:HOH2114 4.8 22.6 1.0 SG B:CYS154 4.8 26.1 1.0 C B:ILE152 4.9 23.0 1.0 CA B:ILE152 5.0 21.5 1.0

Iron binding site 9 out of 22 in the Quinol:Fumarate Reductase From Wolinella Succinogenes


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 9 of Quinol:Fumarate Reductase From Wolinella Succinogenes within 5.0Å range: probe atom residue distance (Å) B Occ B:Fe1242 b:25.0 occ:1.00 FE4 B:SF41242 0.0 25.0 1.0 SG B:CYS218 2.2 27.2 1.0 S3 B:SF41242 2.3 24.0 1.0 S2 B:SF41242 2.3 24.6 1.0 S1 B:SF41242 2.3 24.4 1.0 FE1 B:SF41242 2.7 25.2 1.0 FE2 B:SF41242 2.8 24.5 1.0 FE3 B:SF41242 2.8 25.2 1.0 CB B:CYS218 3.4 26.5 1.0 CA B:CYS218 3.9 25.7 1.0 S4 B:SF41242 3.9 22.2 1.0 CD B:PRO219 4.3 27.3 1.0 C B:CYS218 4.6 28.0 1.0 SG B:CYS157 4.6 24.5 1.0 SG B:CYS154 4.6 26.1 1.0 N B:PRO219 4.7 29.5 1.0 CD1 B:LEU224 4.7 21.4 1.0 CD2 B:LEU222 4.8 30.4 1.0 CD1 B:LEU222 4.8 31.2 1.0 SG B:CYS151 4.9 24.0 1.0 CB B:CYS157 4.9 23.9 1.0 N B:LYS220 5.0 29.0 1.0

Iron binding site 10 out of 22 in the Quinol:Fumarate Reductase From Wolinella Succinogenes


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 10 of Quinol:Fumarate Reductase From Wolinella Succinogenes within 5.0Å range: probe atom residue distance (Å) B Occ C:Fe1255 b:29.8 occ:1.00 FE C:HEM1255 0.0 29.8 1.0 NA C:HEM1255 2.0 30.9 1.0 NE2 C:HIS93 2.0 29.7 1.0 NE2 C:HIS182 2.0 30.5 1.0 NB C:HEM1255 2.0 32.3 1.0 ND C:HEM1255 2.0 29.8 1.0 NC C:HEM1255 2.1 32.2 1.0 CD2 C:HIS182 3.0 32.8 1.0 CD2 C:HIS93 3.0 28.3 1.0 C1A C:HEM1255 3.0 32.2 1.0 CE1 C:HIS93 3.0 29.4 1.0 C4A C:HEM1255 3.0 31.2 1.0 CE1 C:HIS182 3.0 30.6 1.0 C1B C:HEM1255 3.1 32.6 1.0 C4D C:HEM1255 3.1 31.0 1.0 C4B C:HEM1255 3.1 33.9 1.0 C1D C:HEM1255 3.1 30.8 1.0 C1C C:HEM1255 3.1 32.1 1.0 C4C C:HEM1255 3.1 31.7 1.0 CHB C:HEM1255 3.4 31.1 1.0 CHA C:HEM1255 3.4 30.9 1.0 CHC C:HEM1255 3.5 33.8 1.0 CHD C:HEM1255 3.5 30.9 1.0 ND1 C:HIS93 4.1 28.9 1.0 ND1 C:HIS182 4.1 32.2 1.0 CG C:HIS182 4.1 32.8 1.0 CG C:HIS93 4.1 29.9 1.0 C2A C:HEM1255 4.2 31.7 1.0 C3A C:HEM1255 4.2 32.3 1.0 C2B C:HEM1255 4.3 31.8 1.0 C3B C:HEM1255 4.3 33.6 1.0 C3D C:HEM1255 4.3 29.2 1.0 C2D C:HEM1255 4.3 30.2 1.0 O C:HOH2045 4.3 28.0 1.0 C3C C:HEM1255 4.3 31.8 1.0 C2C C:HEM1255 4.3 32.4 1.0

M.G.Madej, H.R.Nasiri, N.S.Hilgendorff, H.Schwalbe, C.R.D.Lancaster. Evidence For Transmembrane Proton Transfer in A Dihaem-Containing Membrane Protein Complex. Embo J. V. 25 4963 2006.
ISSN: ISSN 0261-4189
PubMed: 17024183
DOI: 10.1038/SJ.EMBOJ.7601361