Iron in PDB 2g6o: Structure of Bovine Enos Heme Domain (BH4-Free) Complexed with Co

All present enzymatic activity of Structure of Bovine Enos Heme Domain (BH4-Free) Complexed with Co:
1.14.13.39;

The structure of Structure of Bovine Enos Heme Domain (BH4-Free) Complexed with Co, PDB code: 2g6o was solved by H.Li, J.Igarashi, J.Jamal, W.Yang, T.L.Poulos, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	34.96 / 1.90
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	57.698, 106.382, 155.897, 90.00, 90.00, 90.00
R / Rfree (%)	20.8 / 24

The structure of Structure of Bovine Enos Heme Domain (BH4-Free) Complexed with Co also contains other interesting chemical elements:

Arsenic	(As)	2 atoms
Zinc	(Zn)	1 atom

The binding sites of Iron atom in the Structure of Bovine Enos Heme Domain (BH4-Free) Complexed with Co (pdb code 2g6o). This binding sites where shown within 5.0 Angstroms radius around Iron atom.
In total 2 binding sites of Iron where determined in the Structure of Bovine Enos Heme Domain (BH4-Free) Complexed with Co, PDB code: 2g6o:
Jump to Iron binding site number: 1; 2;

Iron binding site 1 out of 2 in the Structure of Bovine Enos Heme Domain (BH4-Free) Complexed with Co


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 1 of Structure of Bovine Enos Heme Domain (BH4-Free) Complexed with Co within 5.0Å range: probe atom residue distance (Å) B Occ A:Fe500 b:26.2 occ:1.00 FE A:HEM500 0.0 26.2 1.0 C A:CMO920 1.7 33.1 1.0 NB A:HEM500 2.0 24.4 1.0 NA A:HEM500 2.0 26.8 1.0 NC A:HEM500 2.0 24.0 1.0 ND A:HEM500 2.0 24.8 1.0 SG A:CYS186 2.4 24.4 1.0 O A:CMO920 2.8 35.1 1.0 C1B A:HEM500 3.1 25.7 1.0 C1A A:HEM500 3.1 26.9 1.0 C4B A:HEM500 3.1 24.4 1.0 C4A A:HEM500 3.1 27.0 1.0 C4D A:HEM500 3.1 26.2 1.0 C1D A:HEM500 3.1 26.1 1.0 C1C A:HEM500 3.1 23.8 1.0 C4C A:HEM500 3.1 23.8 1.0 CB A:CYS186 3.4 24.4 1.0 CHB A:HEM500 3.4 25.8 1.0 CHA A:HEM500 3.5 26.1 1.0 CHC A:HEM500 3.5 24.1 1.0 CHD A:HEM500 3.5 24.9 1.0 CA A:CYS186 4.1 24.8 1.0 CZ A:ARG700 4.3 39.6 1.0 C2A A:HEM500 4.3 27.9 1.0 C2B A:HEM500 4.3 25.3 1.0 C3B A:HEM500 4.3 25.2 1.0 C3A A:HEM500 4.3 27.6 1.0 C2C A:HEM500 4.3 23.4 1.0 C3D A:HEM500 4.3 27.3 1.0 C2D A:HEM500 4.3 26.5 1.0 C3C A:HEM500 4.3 23.3 1.0 NE1 A:TRP180 4.5 22.6 1.0 NE A:ARG700 4.8 39.5 1.0 CD A:ARG700 4.9 38.6 1.0 C A:CYS186 4.9 24.6 1.0 N A:GLY188 4.9 24.2 1.0 N A:VAL187 4.9 24.2 1.0

Iron binding site 2 out of 2 in the Structure of Bovine Enos Heme Domain (BH4-Free) Complexed with Co


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 2 of Structure of Bovine Enos Heme Domain (BH4-Free) Complexed with Co within 5.0Å range: probe atom residue distance (Å) B Occ B:Fe500 b:27.5 occ:1.00 FE B:HEM500 0.0 27.5 1.0 C B:CMO920 1.7 34.2 1.0 NB B:HEM500 2.0 26.9 1.0 ND B:HEM500 2.0 27.8 1.0 NA B:HEM500 2.0 28.4 1.0 NC B:HEM500 2.0 26.9 1.0 SG B:CYS186 2.4 25.8 1.0 O B:CMO920 2.8 35.0 1.0 C1B B:HEM500 3.1 26.9 1.0 C4A B:HEM500 3.1 27.9 1.0 C4C B:HEM500 3.1 26.4 1.0 C4B B:HEM500 3.1 27.1 1.0 C1D B:HEM500 3.1 27.8 1.0 C1C B:HEM500 3.1 27.3 1.0 C4D B:HEM500 3.1 28.5 1.0 C1A B:HEM500 3.1 28.8 1.0 CB B:CYS186 3.4 24.7 1.0 CHB B:HEM500 3.4 26.8 1.0 CHD B:HEM500 3.5 26.8 1.0 CHC B:HEM500 3.5 27.2 1.0 CHA B:HEM500 3.5 28.6 1.0 CA B:CYS186 4.1 24.9 1.0 NH1 B:ARG701 4.2 38.9 1.0 C2B B:HEM500 4.3 26.6 1.0 C3A B:HEM500 4.3 28.7 1.0 C3D B:HEM500 4.3 29.3 1.0 C3B B:HEM500 4.3 26.5 1.0 C2C B:HEM500 4.3 27.1 1.0 C2A B:HEM500 4.3 30.1 1.0 C2D B:HEM500 4.3 28.1 1.0 C3C B:HEM500 4.3 26.4 1.0 NE1 B:TRP180 4.4 25.8 1.0 CZ B:ARG701 4.6 39.1 1.0 C B:CYS186 4.9 24.1 1.0 NE B:ARG701 4.9 39.3 1.0 N B:GLY188 4.9 25.2 1.0 N B:VAL187 5.0 24.4 1.0

H.Li, J.Igarashi, J.Jamal, W.Yang, T.L.Poulos. Structural Studies of Constitutive Nitric Oxide Synthases with Diatomic Ligands Bound. J.Biol.Inorg.Chem. V. 11 753 2006.
ISSN: ISSN 0949-8257
PubMed: 16804678
DOI: 10.1007/S00775-006-0123-8