Iron in PDB 2h35: Solution Structure of Human Normal Adult Hemoglobin

The binding sites of Iron atom in the Solution Structure of Human Normal Adult Hemoglobin (pdb code 2h35). This binding sites where shown within 5.0 Angstroms radius around Iron atom.
In total 4 binding sites of Iron where determined in the Solution Structure of Human Normal Adult Hemoglobin, PDB code: 2h35:
Jump to Iron binding site number: 1; 2; 3; 4;

Iron binding site 1 out of 4 in the Solution Structure of Human Normal Adult Hemoglobin


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 1 of Solution Structure of Human Normal Adult Hemoglobin within 5.0Å range: probe atom residue distance (Å) B Occ A:Fe142 b:0.0 occ:1.00 FE A:HEC142 0.0 0.0 1.0 NC A:HEC142 2.0 0.0 1.0 NA A:HEC142 2.0 0.0 1.0 ND A:HEC142 2.0 0.0 1.0 NB A:HEC142 2.0 0.0 1.0 HE2 A:HIS87 2.5 0.0 1.0 HE2 A:HIS58 2.7 0.0 1.0 C1C A:HEC142 3.0 0.0 1.0 C4C A:HEC142 3.0 0.0 1.0 C1B A:HEC142 3.0 0.0 1.0 C1A A:HEC142 3.0 0.0 1.0 C4D A:HEC142 3.0 0.0 1.0 C4A A:HEC142 3.0 0.0 1.0 C1D A:HEC142 3.0 0.0 1.0 C4B A:HEC142 3.0 0.0 1.0 NE2 A:HIS87 3.3 0.0 1.0 CHB A:HEC142 3.4 0.0 1.0 CHA A:HEC142 3.4 0.0 1.0 CHC A:HEC142 3.4 0.0 1.0 CHD A:HEC142 3.4 0.0 1.0 NE2 A:HIS58 3.5 0.0 1.0 HE1 A:HIS87 4.0 0.0 1.0 CE1 A:HIS87 4.0 0.0 1.0 HE1 A:HIS58 4.2 0.0 1.0 CE1 A:HIS58 4.2 0.0 1.0 C2C A:HEC142 4.2 0.0 1.0 C3C A:HEC142 4.2 0.0 1.0 C2A A:HEC142 4.2 0.0 1.0 C2B A:HEC142 4.2 0.0 1.0 C3D A:HEC142 4.2 0.0 1.0 C2D A:HEC142 4.2 0.0 1.0 C3A A:HEC142 4.2 0.0 1.0 C3B A:HEC142 4.3 0.0 1.0 HG21 A:VAL62 4.3 0.0 1.0 CD2 A:HIS87 4.3 0.0 1.0 HHB A:HEC142 4.5 0.0 1.0 HHC A:HEC142 4.5 0.0 1.0 HHD A:HEC142 4.5 0.0 1.0 HHA A:HEC142 4.5 0.0 1.0 CD2 A:HIS58 4.5 0.0 1.0 HD22 A:LEU136 4.5 0.0 1.0 HD2 A:HIS87 4.6 0.0 1.0 HD2 A:HIS58 4.7 0.0 1.0

Iron binding site 2 out of 4 in the Solution Structure of Human Normal Adult Hemoglobin


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 2 of Solution Structure of Human Normal Adult Hemoglobin within 5.0Å range: probe atom residue distance (Å) B Occ B:Fe147 b:0.0 occ:1.00 FE B:HEC147 0.0 0.0 1.0 NC B:HEC147 2.0 0.0 1.0 ND B:HEC147 2.0 0.0 1.0 NA B:HEC147 2.0 0.0 1.0 NB B:HEC147 2.0 0.0 1.0 HE2 B:HIS92 2.6 0.0 1.0 C1C B:HEC147 3.0 0.0 1.0 C4C B:HEC147 3.0 0.0 1.0 C1D B:HEC147 3.0 0.0 1.0 C4B B:HEC147 3.0 0.0 1.0 C4D B:HEC147 3.0 0.0 1.0 C4A B:HEC147 3.0 0.0 1.0 C1A B:HEC147 3.0 0.0 1.0 C1B B:HEC147 3.0 0.0 1.0 HE1 B:HIS63 3.2 0.0 1.0 HG23 B:VAL67 3.2 0.0 1.0 CHD B:HEC147 3.4 0.0 1.0 CHC B:HEC147 3.4 0.0 1.0 CHA B:HEC147 3.4 0.0 1.0 CHB B:HEC147 3.4 0.0 1.0 NE2 B:HIS92 3.4 0.0 1.0 HD2 B:HIS92 3.7 0.0 1.0 CD2 B:HIS92 4.0 0.0 1.0 HG21 B:VAL67 4.0 0.0 1.0 CG2 B:VAL67 4.0 0.0 1.0 CE1 B:HIS63 4.2 0.0 1.0 C3C B:HEC147 4.2 0.0 1.0 C2C B:HEC147 4.2 0.0 1.0 C3B B:HEC147 4.2 0.0 1.0 C2D B:HEC147 4.2 0.0 1.0 C2A B:HEC147 4.2 0.0 1.0 C3D B:HEC147 4.2 0.0 1.0 C3A B:HEC147 4.2 0.0 1.0 C2B B:HEC147 4.2 0.0 1.0 HG22 B:VAL67 4.4 0.0 1.0 HHA B:HEC147 4.5 0.0 1.0 HHD B:HEC147 4.5 0.0 1.0 HHB B:HEC147 4.5 0.0 1.0 HHC B:HEC147 4.5 0.0 1.0 CE1 B:HIS92 4.6 0.0 1.0 HD13 B:LEU96 4.8 0.0 1.0 HE2 B:HIS63 4.8 0.0 1.0 NE2 B:HIS63 4.9 0.0 1.0 HD12 B:LEU96 4.9 0.0 1.0 HE1 B:PHE42 5.0 0.0 1.0 HE1 B:HIS92 5.0 0.0 1.0

Iron binding site 3 out of 4 in the Solution Structure of Human Normal Adult Hemoglobin


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 3 of Solution Structure of Human Normal Adult Hemoglobin within 5.0Å range: probe atom residue distance (Å) B Occ C:Fe142 b:0.0 occ:1.00 FE C:HEC142 0.0 0.0 1.0 NC C:HEC142 2.0 0.0 1.0 NA C:HEC142 2.0 0.0 1.0 NB C:HEC142 2.0 0.0 1.0 ND C:HEC142 2.0 0.0 1.0 HE2 C:HIS87 2.5 0.0 1.0 HE2 C:HIS58 2.7 0.0 1.0 C1C C:HEC142 3.0 0.0 1.0 C4C C:HEC142 3.0 0.0 1.0 C1B C:HEC142 3.0 0.0 1.0 C1A C:HEC142 3.0 0.0 1.0 C4D C:HEC142 3.0 0.0 1.0 C4A C:HEC142 3.0 0.0 1.0 C1D C:HEC142 3.0 0.0 1.0 C4B C:HEC142 3.0 0.0 1.0 NE2 C:HIS87 3.3 0.0 1.0 CHB C:HEC142 3.4 0.0 1.0 CHA C:HEC142 3.4 0.0 1.0 CHD C:HEC142 3.4 0.0 1.0 CHC C:HEC142 3.4 0.0 1.0 NE2 C:HIS58 3.5 0.0 1.0 HE1 C:HIS87 4.0 0.0 1.0 CE1 C:HIS87 4.0 0.0 1.0 HE1 C:HIS58 4.2 0.0 1.0 CE1 C:HIS58 4.2 0.0 1.0 C2C C:HEC142 4.2 0.0 1.0 C3C C:HEC142 4.2 0.0 1.0 C2A C:HEC142 4.2 0.0 1.0 C2B C:HEC142 4.2 0.0 1.0 C3D C:HEC142 4.2 0.0 1.0 C3A C:HEC142 4.2 0.0 1.0 C2D C:HEC142 4.2 0.0 1.0 C3B C:HEC142 4.2 0.0 1.0 HG21 C:VAL62 4.3 0.0 1.0 CD2 C:HIS87 4.3 0.0 1.0 HHB C:HEC142 4.5 0.0 1.0 HHC C:HEC142 4.5 0.0 1.0 HHA C:HEC142 4.5 0.0 1.0 HHD C:HEC142 4.5 0.0 1.0 CD2 C:HIS58 4.5 0.0 1.0 HD22 C:LEU136 4.5 0.0 1.0 HD2 C:HIS87 4.6 0.0 1.0 HD2 C:HIS58 4.7 0.0 1.0

Iron binding site 4 out of 4 in the Solution Structure of Human Normal Adult Hemoglobin


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 4 of Solution Structure of Human Normal Adult Hemoglobin within 5.0Å range: probe atom residue distance (Å) B Occ D:Fe147 b:0.0 occ:1.00 FE D:HEC147 0.0 0.0 1.0 NC D:HEC147 2.0 0.0 1.0 NA D:HEC147 2.0 0.0 1.0 ND D:HEC147 2.0 0.0 1.0 NB D:HEC147 2.0 0.0 1.0 HE2 D:HIS92 2.6 0.0 1.0 C1C D:HEC147 3.0 0.0 1.0 C4C D:HEC147 3.0 0.0 1.0 C4A D:HEC147 3.0 0.0 1.0 C4B D:HEC147 3.0 0.0 1.0 C1D D:HEC147 3.0 0.0 1.0 C1A D:HEC147 3.0 0.0 1.0 C4D D:HEC147 3.0 0.0 1.0 C1B D:HEC147 3.0 0.0 1.0 HE1 D:HIS63 3.2 0.0 1.0 HG23 D:VAL67 3.2 0.0 1.0 CHC D:HEC147 3.4 0.0 1.0 CHA D:HEC147 3.4 0.0 1.0 CHD D:HEC147 3.4 0.0 1.0 CHB D:HEC147 3.4 0.0 1.0 NE2 D:HIS92 3.4 0.0 1.0 HD2 D:HIS92 3.7 0.0 1.0 CD2 D:HIS92 4.0 0.0 1.0 HG21 D:VAL67 4.0 0.0 1.0 CG2 D:VAL67 4.0 0.0 1.0 CE1 D:HIS63 4.2 0.0 1.0 C3C D:HEC147 4.2 0.0 1.0 C2C D:HEC147 4.2 0.0 1.0 C3B D:HEC147 4.2 0.0 1.0 C3A D:HEC147 4.2 0.0 1.0 C2D D:HEC147 4.2 0.0 1.0 C3D D:HEC147 4.2 0.0 1.0 C2A D:HEC147 4.2 0.0 1.0 C2B D:HEC147 4.2 0.0 1.0 HG22 D:VAL67 4.4 0.0 1.0 HHB D:HEC147 4.5 0.0 1.0 HHA D:HEC147 4.5 0.0 1.0 HHC D:HEC147 4.5 0.0 1.0 HHD D:HEC147 4.5 0.0 1.0 CE1 D:HIS92 4.6 0.0 1.0 HD13 D:LEU96 4.8 0.0 1.0 HE2 D:HIS63 4.8 0.0 1.0 NE2 D:HIS63 4.9 0.0 1.0 HD12 D:LEU96 4.9 0.0 1.0 HE1 D:PHE42 5.0 0.0 1.0 HE1 D:HIS92 5.0 0.0 1.0

Y.Xu, Y.Zheng, J.S.Fan, D.Yang. A New Strategy For Structure Determination of Large Proteins in Solution Without Deuteration Nat.Methods V. 3 931 2006.
ISSN: ISSN 1548-7091
PubMed: 17060917
DOI: 10.1038/NMETH938