Iron in PDB 2h7q: Cytochrome P450CAM Complexed with Imidazole

All present enzymatic activity of Cytochrome P450CAM Complexed with Imidazole:
1.14.15.1;

The structure of Cytochrome P450CAM Complexed with Imidazole, PDB code: 2h7q was solved by A.Verras, A.Alian, P.R.Montellano, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	35.00 / 1.50
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	36.667, 103.750, 106.485, 90.00, 90.00, 90.00
R / Rfree (%)	21 / 23.9

The binding sites of Iron atom in the Cytochrome P450CAM Complexed with Imidazole (pdb code 2h7q). This binding sites where shown within 5.0 Angstroms radius around Iron atom.
In total only one binding site of Iron was determined in the Cytochrome P450CAM Complexed with Imidazole, PDB code: 2h7q:

Iron binding site 1 out of 1 in the Cytochrome P450CAM Complexed with Imidazole


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 1 of Cytochrome P450CAM Complexed with Imidazole within 5.0Å range: probe atom residue distance (Å) B Occ A:Fe415 b:11.4 occ:1.00 FE A:HEM415 0.0 11.4 1.0 ND A:HEM415 2.0 11.0 1.0 NA A:HEM415 2.1 10.6 1.0 NB A:HEM415 2.1 9.7 1.0 NC A:HEM415 2.1 10.1 1.0 N3 A:IMD3026 2.1 7.7 1.0 SG A:CYS357 2.3 11.1 1.0 C2 A:IMD3026 3.0 18.6 0.8 C1D A:HEM415 3.1 13.0 1.0 C4D A:HEM415 3.1 11.0 1.0 C4C A:HEM415 3.1 10.8 1.0 C1A A:HEM415 3.1 8.9 1.0 C4A A:HEM415 3.1 9.9 1.0 C4B A:HEM415 3.1 8.7 1.0 C1B A:HEM415 3.1 8.4 1.0 C1C A:HEM415 3.1 9.8 1.0 C4 A:IMD3026 3.2 21.4 0.5 CB A:CYS357 3.4 9.4 1.0 CHD A:HEM415 3.4 10.9 1.0 CHA A:HEM415 3.4 9.8 1.0 CHB A:HEM415 3.4 10.9 1.0 CHC A:HEM415 3.5 9.6 1.0 N1 A:IMD3026 4.1 21.8 0.6 CA A:CYS357 4.2 10.6 1.0 C5 A:IMD3026 4.2 20.4 0.6 C2D A:HEM415 4.3 14.1 1.0 C3D A:HEM415 4.3 13.6 1.0 C3A A:HEM415 4.3 10.3 1.0 C2A A:HEM415 4.3 10.9 1.0 C3B A:HEM415 4.3 8.9 1.0 C2B A:HEM415 4.3 8.8 1.0 C3C A:HEM415 4.3 11.0 1.0 C2C A:HEM415 4.4 9.9 1.0 N A:GLY359 4.7 11.1 1.0 C A:CYS357 4.8 11.2 1.0 N A:LEU358 4.9 10.9 1.0 O A:HOH3452 4.9 38.6 0.7

A.Verras, A.Alian, P.R.Montellano. Cytochrome P450 Active Site Plasticity: Attenuation of Imidazole Binding in Cytochrome P450CAM By An L244A Mutation. Protein Eng.Des.Sel. V. 19 491 2006.
ISSN: ISSN 1741-0126
PubMed: 16943206
DOI: 10.1093/PROTEIN/GZL035