Iron in PDB 2hbu: Crystal Structure of Hif Prolyl Hydroxylase Egln-1 in Complex with A Biologically Active Inhibitor

The structure of Crystal Structure of Hif Prolyl Hydroxylase Egln-1 in Complex with A Biologically Active Inhibitor, PDB code: 2hbu was solved by A.G.Evdokimov, R.L.Walter, M.Mekel, M.E.Pokross, R.Kawamoto, A.Boyer, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	32.53 / 1.85
Space group	P 63
Cell size a, b, c (Å), α, β, γ (°)	111.045, 111.045, 40.126, 90.00, 90.00, 120.00
R / Rfree (%)	17.9 / 23.1

The structure of Crystal Structure of Hif Prolyl Hydroxylase Egln-1 in Complex with A Biologically Active Inhibitor also contains other interesting chemical elements:

Chlorine

(Cl)

1 atom

The binding sites of Iron atom in the Crystal Structure of Hif Prolyl Hydroxylase Egln-1 in Complex with A Biologically Active Inhibitor (pdb code 2hbu). This binding sites where shown within 5.0 Angstroms radius around Iron atom.
In total only one binding site of Iron was determined in the Crystal Structure of Hif Prolyl Hydroxylase Egln-1 in Complex with A Biologically Active Inhibitor, PDB code: 2hbu:

Iron binding site 1 out of 1 in the Crystal Structure of Hif Prolyl Hydroxylase Egln-1 in Complex with A Biologically Active Inhibitor


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 1 of Crystal Structure of Hif Prolyl Hydroxylase Egln-1 in Complex with A Biologically Active Inhibitor within 5.0Å range: probe atom residue distance (Å) B Occ A:Fe900 b:17.7 occ:1.00 O13 A:UN91 2.1 19.8 1.0 NE2 A:HIS313 2.1 18.8 1.0 OD2 A:ASP315 2.1 20.3 1.0 NE2 A:HIS374 2.1 21.1 1.0 O A:HOH993 2.1 17.9 1.0 N8 A:UN91 2.2 21.5 1.0 C12 A:UN91 2.9 15.3 1.0 CE1 A:HIS313 3.0 19.9 1.0 C9 A:UN91 3.1 14.2 1.0 CE1 A:HIS374 3.1 22.1 1.0 CD2 A:HIS374 3.1 20.1 1.0 CD2 A:HIS313 3.1 19.2 1.0 CG A:ASP315 3.1 21.7 1.0 C7 A:UN91 3.2 18.7 1.0 OD1 A:ASP315 3.4 20.8 1.0 CL1 A:UN91 3.5 24.1 1.0 ND1 A:HIS313 4.2 21.0 1.0 ND1 A:HIS374 4.2 21.1 1.0 N14 A:UN91 4.2 22.1 1.0 CG A:HIS374 4.2 23.1 1.0 CG A:HIS313 4.2 22.4 1.0 O A:HOH901 4.2 19.8 1.0 C10 A:UN91 4.4 20.1 1.0 CB A:ASP315 4.5 21.7 1.0 C2 A:UN91 4.6 16.2 1.0 C15 A:UN91 4.7 19.2 1.0 CZ A:PHE366 4.8 18.2 1.0 CA A:ASP315 4.8 19.3 1.0

A.G.Evdokimov, R.L.Walter, M.Mekel, M.E.Pokross, R.Kawamoto, A.Boyer. Crystal Structure of Hif Prolyl Hydroxylase in Complex with A Biologically Active Inhibitor To Be Published.