Atomistry » Iron » PDB 2mya-2nwb » 2nse
Atomistry »
  Iron »
    PDB 2mya-2nwb »
      2nse »

Iron in PDB 2nse: Bovine Endothelial Nitric Oxide Synthase Substrate Complex

Enzymatic activity of Bovine Endothelial Nitric Oxide Synthase Substrate Complex

All present enzymatic activity of Bovine Endothelial Nitric Oxide Synthase Substrate Complex:
1.14.13.39;

Protein crystallography data

The structure of Bovine Endothelial Nitric Oxide Synthase Substrate Complex, PDB code: 2nse was solved by C.S.Raman, H.Li, P.Martasek, V.Kral, B.S.S.Masters, T.L.Poulos, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 30.00 / 2.34
Space group P 21 21 21
Cell size a, b, c (Å), α, β, γ (°) 58.060, 106.380, 156.380, 90.00, 90.00, 90.00
R / Rfree (%) 21.6 / 30.5

Other elements in 2nse:

The structure of Bovine Endothelial Nitric Oxide Synthase Substrate Complex also contains other interesting chemical elements:

Arsenic (As) 2 atoms
Zinc (Zn) 1 atom

Iron Binding Sites:

The binding sites of Iron atom in the Bovine Endothelial Nitric Oxide Synthase Substrate Complex (pdb code 2nse). This binding sites where shown within 5.0 Angstroms radius around Iron atom.
In total 2 binding sites of Iron where determined in the Bovine Endothelial Nitric Oxide Synthase Substrate Complex, PDB code: 2nse:
Jump to Iron binding site number: 1; 2;

Iron binding site 1 out of 2 in 2nse

Go back to Iron Binding Sites List in 2nse
Iron binding site 1 out of 2 in the Bovine Endothelial Nitric Oxide Synthase Substrate Complex


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 1 of Bovine Endothelial Nitric Oxide Synthase Substrate Complex within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Fe500

b:15.7
occ:1.00
FE A:HEM500 0.0 15.7 1.0
ND A:HEM500 1.9 4.1 1.0
NB A:HEM500 1.9 4.9 1.0
NA A:HEM500 2.0 17.1 1.0
NC A:HEM500 2.0 25.7 1.0
SG A:CYS186 2.2 28.9 1.0
C4D A:HEM500 2.9 15.4 1.0
C1D A:HEM500 3.0 16.4 1.0
C1B A:HEM500 3.0 15.1 1.0
C4B A:HEM500 3.0 16.6 1.0
C1A A:HEM500 3.0 7.0 1.0
C4A A:HEM500 3.0 12.2 1.0
C1C A:HEM500 3.1 13.2 1.0
C4C A:HEM500 3.1 18.3 1.0
CB A:CYS186 3.2 23.0 1.0
CHA A:HEM500 3.3 9.4 1.0
CHC A:HEM500 3.4 8.6 1.0
CHD A:HEM500 3.4 20.6 1.0
CHB A:HEM500 3.4 11.1 1.0
CA A:CYS186 3.9 21.9 1.0
NH1 A:ARG700 4.0 25.1 1.0
C3D A:HEM500 4.2 14.3 1.0
C2D A:HEM500 4.2 7.9 1.0
C2B A:HEM500 4.2 12.0 1.0
C3B A:HEM500 4.2 21.2 1.0
C2A A:HEM500 4.2 13.4 1.0
C3A A:HEM500 4.3 5.7 1.0
C2C A:HEM500 4.3 16.8 1.0
C3C A:HEM500 4.3 16.6 1.0
CZ A:ARG700 4.4 25.3 1.0
NE1 A:TRP180 4.5 15.2 1.0
NH2 A:ARG700 4.8 15.0 1.0
C A:CYS186 4.8 22.6 1.0
N A:VAL187 4.9 16.6 1.0
N A:GLY188 4.9 25.3 1.0
NE A:ARG700 4.9 28.6 1.0

Iron binding site 2 out of 2 in 2nse

Go back to Iron Binding Sites List in 2nse
Iron binding site 2 out of 2 in the Bovine Endothelial Nitric Oxide Synthase Substrate Complex


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 2 of Bovine Endothelial Nitric Oxide Synthase Substrate Complex within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Fe500

b:29.4
occ:1.00
FE B:HEM500 0.0 29.4 1.0
ND B:HEM500 2.0 31.3 1.0
NB B:HEM500 2.0 37.9 1.0
NA B:HEM500 2.0 40.7 1.0
NC B:HEM500 2.0 37.7 1.0
SG B:CYS186 2.2 23.9 1.0
C1D B:HEM500 3.0 37.8 1.0
C4D B:HEM500 3.0 33.6 1.0
C4B B:HEM500 3.0 40.9 1.0
C1A B:HEM500 3.0 38.1 1.0
C1B B:HEM500 3.1 37.1 1.0
C4C B:HEM500 3.1 34.5 1.0
C1C B:HEM500 3.1 33.4 1.0
C4A B:HEM500 3.1 34.9 1.0
NH1 B:ARG700 3.2 41.7 1.0
CHD B:HEM500 3.4 40.0 1.0
CHA B:HEM500 3.4 36.7 1.0
CHC B:HEM500 3.4 35.9 1.0
CHB B:HEM500 3.5 35.9 1.0
CB B:CYS186 3.5 34.4 1.0
NE1 B:TRP180 4.1 34.7 1.0
CA B:CYS186 4.1 29.8 1.0
CZ B:ARG700 4.2 39.9 1.0
C3D B:HEM500 4.3 34.9 1.0
C2D B:HEM500 4.3 33.4 1.0
C2A B:HEM500 4.3 35.2 1.0
C3B B:HEM500 4.3 41.9 1.0
C2B B:HEM500 4.3 36.7 1.0
C3A B:HEM500 4.3 33.3 1.0
C2C B:HEM500 4.3 32.4 1.0
C3C B:HEM500 4.3 35.4 1.0
NH2 B:ARG700 4.7 33.7 1.0
N B:GLY188 4.7 31.2 1.0
N B:VAL187 4.8 23.9 1.0
CD1 B:TRP180 4.9 31.8 1.0
C B:CYS186 4.9 29.1 1.0
CE2 B:TRP180 5.0 38.3 1.0

Reference:

C.S.Raman, H.Li, P.Martasek, V.Kral, B.S.Masters, T.L.Poulos. Crystal Structure of Constitutive Endothelial Nitric Oxide Synthase: A Paradigm For Pterin Function Involving A Novel Metal Center. Cell(Cambridge,Mass.) V. 95 939 1998.
ISSN: ISSN 0092-8674
PubMed: 9875848
DOI: 10.1016/S0092-8674(00)81718-3
Page generated: Sun Dec 13 14:49:50 2020

Last articles

Tb in 6TVY
Si in 6Y7O
Rh in 6WRM
Rh in 6WRL
Ni in 6Y8Z
Ni in 6Y8Y
Na in 6ZXZ
Na in 7ACG
Na in 6YLS
Na in 6Y8Z
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy