Iron in PDB 2o1z: Plasmodium Vivax Ribonucleotide Reductase Subunit R2 (PV086155)

The structure of Plasmodium Vivax Ribonucleotide Reductase Subunit R2 (PV086155), PDB code: 2o1z was solved by A.Dong, W.Tempel, W.Qiu, J.Lew, A.K.Wernimont, Y.H.Lin, A.Hassanali, M.Melone, Y.Zhao, P.Nordlund, C.H.Arrowsmith, A.M.Edwards, J.Weigelt, M.Sundstrom, A.Bochkarev, R.Hui, J.D.Artz, M.Amani, Structural Genomicsconsortium (Sgc), with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	37.32 / 2.40
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	76.151, 79.978, 103.846, 90.00, 90.00, 90.00
R / Rfree (%)	21.8 / 28.5

The binding sites of Iron atom in the Plasmodium Vivax Ribonucleotide Reductase Subunit R2 (PV086155) (pdb code 2o1z). This binding sites where shown within 5.0 Angstroms radius around Iron atom.
In total 2 binding sites of Iron where determined in the Plasmodium Vivax Ribonucleotide Reductase Subunit R2 (PV086155), PDB code: 2o1z:
Jump to Iron binding site number: 1; 2;

Iron binding site 1 out of 2 in the Plasmodium Vivax Ribonucleotide Reductase Subunit R2 (PV086155)


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 1 of Plasmodium Vivax Ribonucleotide Reductase Subunit R2 (PV086155) within 5.0Å range: probe atom residue distance (Å) B Occ A:Fe1000 b:54.7 occ:1.00 OE1 A:GLU225 2.3 32.2 1.0 ND1 A:HIS228 2.4 17.7 1.0 OE1 A:GLU191 2.7 38.1 1.0 OE1 A:GLU129 2.8 32.2 1.0 CD A:GLU225 2.9 31.0 1.0 OE2 A:GLU225 3.0 34.8 1.0 CG A:GLU191 3.2 32.9 1.0 CE1 A:HIS228 3.3 18.4 1.0 CD A:GLU191 3.4 35.5 1.0 CG A:HIS228 3.4 18.1 1.0 NE2 A:GLN125 3.6 23.5 1.0 CB A:HIS228 3.7 16.7 1.0 CD A:GLU129 3.8 27.5 1.0 CG A:GLU129 3.9 25.2 1.0 CG A:GLU225 4.3 26.5 1.0 CA A:GLU225 4.3 21.0 1.0 NE2 A:HIS228 4.5 20.0 1.0 CD2 A:HIS228 4.5 19.9 1.0 CB A:GLU225 4.6 24.1 1.0 CD A:GLN125 4.6 23.2 1.0 OE2 A:GLU191 4.6 36.6 1.0 CB A:GLU191 4.6 28.0 1.0 O A:HOH2071 4.7 41.2 1.0 CG A:GLN125 4.8 22.1 1.0 N A:GLU225 4.8 19.9 1.0 CE1 A:HIS132 4.9 14.5 1.0 OE2 A:GLU129 5.0 30.6 1.0

Iron binding site 2 out of 2 in the Plasmodium Vivax Ribonucleotide Reductase Subunit R2 (PV086155)


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 2 of Plasmodium Vivax Ribonucleotide Reductase Subunit R2 (PV086155) within 5.0Å range: probe atom residue distance (Å) B Occ B:Fe1001 b:48.2 occ:1.00 OE2 B:GLU225 2.1 30.1 1.0 OE1 B:GLU191 2.2 38.5 1.0 ND1 B:HIS228 2.4 19.1 1.0 OE2 B:GLU129 2.6 33.5 1.0 OE1 B:GLU129 2.8 32.5 1.0 CD B:GLU129 3.0 32.2 1.0 CE1 B:HIS228 3.1 21.3 1.0 CD B:GLU225 3.1 29.0 1.0 CD B:GLU191 3.2 38.2 1.0 CG B:HIS228 3.4 17.9 1.0 OE2 B:GLU191 3.5 42.9 1.0 O B:HOH1059 3.5 45.1 1.0 OE1 B:GLU225 3.6 33.1 1.0 NE2 B:GLN125 3.7 27.6 1.0 CB B:HIS228 3.8 15.0 1.0 NE2 B:HIS228 4.3 22.9 1.0 CD2 B:HIS228 4.4 20.4 1.0 CG B:GLU225 4.4 26.1 1.0 CG B:GLU129 4.5 29.2 1.0 CD B:GLN125 4.6 25.1 1.0 CG B:GLU191 4.6 34.4 1.0 CA B:GLU225 4.6 20.5 1.0 CG B:GLN125 4.6 24.9 1.0 CE1 B:HIS132 4.9 14.4 1.0 ND1 B:HIS132 5.0 13.6 1.0 CB B:GLU225 5.0 23.4 1.0

A.Dong, W.Tempel, W.Qiu, J.Lew, A.K.Wernimont, Y.H.Lin, A.Hassanali, M.Melone, Y.Zhao, P.Nordlund, C.H.Arrowsmith, A.M.Edwards, J.Weigelt, M.Sundstrom, A.Bochkarev, R.Hui, J.D.Artz, M.Amani. Crystal Structure of Plasmodium Vivax Ribonucleotide Reductase Subunit R2 (PV086155) To Be Published.