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Atomistry » Iron » PDB 2orl-2pg7 » 2orr » |
Iron in PDB 2orr: Murine Inducible Nitric Oxide Synthase Oxygenase Domain (Delta 114) 4-(Benzo[1,3]Dioxol-5-Yloxy)-2-(4-Imidazol-1- Yl-Phenoxy)-Pyrimidine ComplexEnzymatic activity of Murine Inducible Nitric Oxide Synthase Oxygenase Domain (Delta 114) 4-(Benzo[1,3]Dioxol-5-Yloxy)-2-(4-Imidazol-1- Yl-Phenoxy)-Pyrimidine Complex
All present enzymatic activity of Murine Inducible Nitric Oxide Synthase Oxygenase Domain (Delta 114) 4-(Benzo[1,3]Dioxol-5-Yloxy)-2-(4-Imidazol-1- Yl-Phenoxy)-Pyrimidine Complex:
1.14.13.39; Protein crystallography data
The structure of Murine Inducible Nitric Oxide Synthase Oxygenase Domain (Delta 114) 4-(Benzo[1,3]Dioxol-5-Yloxy)-2-(4-Imidazol-1- Yl-Phenoxy)-Pyrimidine Complex, PDB code: 2orr
was solved by
M.Adler,
M.Whitlow,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Iron Binding Sites:
The binding sites of Iron atom in the Murine Inducible Nitric Oxide Synthase Oxygenase Domain (Delta 114) 4-(Benzo[1,3]Dioxol-5-Yloxy)-2-(4-Imidazol-1- Yl-Phenoxy)-Pyrimidine Complex
(pdb code 2orr). This binding sites where shown within
5.0 Angstroms radius around Iron atom.
In total only one binding site of Iron was determined in the Murine Inducible Nitric Oxide Synthase Oxygenase Domain (Delta 114) 4-(Benzo[1,3]Dioxol-5-Yloxy)-2-(4-Imidazol-1- Yl-Phenoxy)-Pyrimidine Complex, PDB code: 2orr: Iron binding site 1 out of 1 in 2orrGo back to Iron Binding Sites List in 2orr
Iron binding site 1 out
of 1 in the Murine Inducible Nitric Oxide Synthase Oxygenase Domain (Delta 114) 4-(Benzo[1,3]Dioxol-5-Yloxy)-2-(4-Imidazol-1- Yl-Phenoxy)-Pyrimidine Complex
Mono view Stereo pair view
Reference:
D.D.Davey,
M.Adler,
D.Arnaia,
K.Eagen,
S.Erickson,
W.Guilford,
M.Kenrick,
M.M.Morrissey,
M.Ohimeyer,
G.Pan,
V.M.Paradkar,
J.Parkinson,
M.Polokoff,
K.Salonz,
C.Santos,
B.Subramanyam,
R.Vergona,
R.G.Wei,
M.Whitlow,
B.Ye,
Z.S.Zhao,
J.J.Devlin,
G.Phillips.
Design, Synthesis, and Activity of 2-Imidazol-1-Ylpyrimidine Derived Inducible Nitric Oxide Synthase Dimerization Inhibitors J.Med.Chem. V. 50 1146 2007.
Page generated: Sun Dec 13 14:50:38 2020
ISSN: ISSN 0022-2623 PubMed: 17315988 DOI: 10.1021/JM061319I |
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