Iron in PDB 2sbl: The Three-Dimensional Structure of An Arachidonic Acid 15- Lipoxygenase

All present enzymatic activity of The Three-Dimensional Structure of An Arachidonic Acid 15- Lipoxygenase:
1.13.11.12;

The structure of The Three-Dimensional Structure of An Arachidonic Acid 15- Lipoxygenase, PDB code: 2sbl was solved by L.M.Amzel, J.C.Boyington, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	N/A / 2.60
Space group	C 1 2 1
Cell size a, b, c (Å), α, β, γ (°)	184.500, 125.600, 94.700, 90.00, 102.90, 90.00
R / Rfree (%)	17.3 / n/a

The binding sites of Iron atom in the The Three-Dimensional Structure of An Arachidonic Acid 15- Lipoxygenase (pdb code 2sbl). This binding sites where shown within 5.0 Angstroms radius around Iron atom.
In total 2 binding sites of Iron where determined in the The Three-Dimensional Structure of An Arachidonic Acid 15- Lipoxygenase, PDB code: 2sbl:
Jump to Iron binding site number: 1; 2;

Iron binding site 1 out of 2 in the The Three-Dimensional Structure of An Arachidonic Acid 15- Lipoxygenase


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 1 of The Three-Dimensional Structure of An Arachidonic Acid 15- Lipoxygenase within 5.0Å range: probe atom residue distance (Å) B Occ B:Fe840 b:43.7 occ:1.00 OXT B:ILE839 2.2 28.8 1.0 NE2 B:HIS504 2.2 25.3 1.0 NE2 B:HIS690 2.2 14.9 1.0 NE2 B:HIS499 2.3 36.3 1.0 C B:ILE839 3.0 19.3 1.0 O B:ILE839 3.0 22.8 1.0 CE1 B:HIS504 3.0 27.0 1.0 CE1 B:HIS499 3.1 38.7 1.0 CE1 B:HIS690 3.1 10.1 1.0 OD1 B:ASN694 3.2 27.2 1.0 CD2 B:HIS690 3.3 11.0 1.0 CD2 B:HIS499 3.3 29.8 1.0 CD2 B:HIS504 3.3 16.6 1.0 CG B:ASN694 3.7 10.2 1.0 ND1 B:HIS504 4.2 24.3 1.0 ND1 B:HIS499 4.3 25.2 1.0 CB B:ASN694 4.3 7.3 1.0 ND1 B:HIS690 4.3 9.1 1.0 CG B:HIS504 4.4 18.3 1.0 CG B:HIS499 4.4 25.4 1.0 ND2 B:ASN694 4.4 5.1 1.0 CG B:HIS690 4.4 11.5 1.0 CA B:ILE839 4.4 18.5 1.0 CG2 B:ILE837 4.5 2.0 1.0 N B:ILE839 4.9 16.1 1.0

Iron binding site 2 out of 2 in the The Three-Dimensional Structure of An Arachidonic Acid 15- Lipoxygenase


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 2 of The Three-Dimensional Structure of An Arachidonic Acid 15- Lipoxygenase within 5.0Å range: probe atom residue distance (Å) B Occ A:Fe840 b:43.7 occ:1.00 OXT A:ILE839 2.2 28.8 1.0 NE2 A:HIS504 2.2 25.3 1.0 NE2 A:HIS690 2.2 14.9 1.0 NE2 A:HIS499 2.3 36.3 1.0 C A:ILE839 3.0 19.3 1.0 O A:ILE839 3.0 22.8 1.0 CE1 A:HIS504 3.0 27.0 1.0 CE1 A:HIS499 3.1 38.7 1.0 CE1 A:HIS690 3.1 10.1 1.0 OD1 A:ASN694 3.2 27.2 1.0 CD2 A:HIS690 3.3 11.0 1.0 CD2 A:HIS499 3.3 29.8 1.0 CD2 A:HIS504 3.3 16.6 1.0 CG A:ASN694 3.7 10.2 1.0 ND1 A:HIS504 4.2 24.3 1.0 ND1 A:HIS499 4.3 25.2 1.0 CB A:ASN694 4.3 7.3 1.0 ND1 A:HIS690 4.3 9.1 1.0 CG A:HIS504 4.4 18.3 1.0 CG A:HIS499 4.4 25.4 1.0 ND2 A:ASN694 4.4 5.1 1.0 CG A:HIS690 4.4 11.5 1.0 CA A:ILE839 4.4 18.5 1.0 CG2 A:ILE837 4.5 2.0 1.0 N A:ILE839 4.9 16.1 1.0

J.C.Boyington, B.J.Gaffney, L.M.Amzel. The Three-Dimensional Structure of An Arachidonic Acid 15-Lipoxygenase. Science V. 260 1482 1993.
ISSN: ISSN 0036-8075
PubMed: 8502991