Iron in PDB 2vz7: Crystal Structure of the Yc-17-Bound Pikc D50N Mutant

The structure of Crystal Structure of the Yc-17-Bound Pikc D50N Mutant, PDB code: 2vz7 was solved by S.Li, D.H.Sherman, L.M.Podust, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	49.67 / 3.20
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	59.862, 109.323, 153.040, 90.00, 90.00, 90.00
R / Rfree (%)	17.9 / 26

The binding sites of Iron atom in the Crystal Structure of the Yc-17-Bound Pikc D50N Mutant (pdb code 2vz7). This binding sites where shown within 5.0 Angstroms radius around Iron atom.
In total 2 binding sites of Iron where determined in the Crystal Structure of the Yc-17-Bound Pikc D50N Mutant, PDB code: 2vz7:
Jump to Iron binding site number: 1; 2;

Iron binding site 1 out of 2 in the Crystal Structure of the Yc-17-Bound Pikc D50N Mutant


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 1 of Crystal Structure of the Yc-17-Bound Pikc D50N Mutant within 5.0Å range: probe atom residue distance (Å) B Occ A:Fe1407 b:29.1 occ:1.00 FE A:HEM1407 0.0 29.1 1.0 NC A:HEM1407 2.0 28.9 1.0 NB A:HEM1407 2.0 29.8 1.0 NA A:HEM1407 2.0 30.3 1.0 ND A:HEM1407 2.0 30.6 1.0 SG A:CYS354 2.8 38.9 1.0 C1C A:HEM1407 3.0 29.2 1.0 C4B A:HEM1407 3.0 29.4 1.0 C4C A:HEM1407 3.0 28.1 1.0 C1D A:HEM1407 3.0 30.2 1.0 C1A A:HEM1407 3.0 30.4 1.0 C1B A:HEM1407 3.0 30.9 1.0 C4A A:HEM1407 3.1 30.5 1.0 C4D A:HEM1407 3.1 30.1 1.0 CHC A:HEM1407 3.4 29.9 1.0 CHD A:HEM1407 3.4 28.4 1.0 CHA A:HEM1407 3.4 30.8 1.0 CHB A:HEM1407 3.5 30.8 1.0 CB A:CYS354 3.6 35.5 1.0 O A:ALA243 4.0 45.7 1.0 CA A:CYS354 4.1 34.0 1.0 C2D A:HEM1407 4.3 31.4 1.0 C3B A:HEM1407 4.3 29.4 1.0 C3A A:HEM1407 4.3 30.0 1.0 C3C A:HEM1407 4.3 28.2 1.0 C2A A:HEM1407 4.3 29.4 1.0 C2B A:HEM1407 4.3 29.7 1.0 C2C A:HEM1407 4.3 28.7 1.0 C3D A:HEM1407 4.3 30.8 1.0 C1 A:PXI1408 4.6 47.1 1.0 N A:ILE355 4.7 29.3 1.0 N A:GLY356 4.7 29.0 1.0 C A:ALA243 4.8 44.5 1.0 C A:CYS354 4.8 31.6 1.0 CB A:ALA243 4.9 40.7 1.0

Iron binding site 2 out of 2 in the Crystal Structure of the Yc-17-Bound Pikc D50N Mutant


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 2 of Crystal Structure of the Yc-17-Bound Pikc D50N Mutant within 5.0Å range: probe atom residue distance (Å) B Occ B:Fe1407 b:29.5 occ:1.00 FE B:HEM1407 0.0 29.5 1.0 ND B:HEM1407 1.9 30.2 1.0 NA B:HEM1407 1.9 29.7 1.0 NC B:HEM1407 2.0 30.8 1.0 NB B:HEM1407 2.0 30.1 1.0 SG B:CYS354 2.9 32.9 1.0 C4D B:HEM1407 3.0 31.4 1.0 C1A B:HEM1407 3.0 29.9 1.0 C1D B:HEM1407 3.0 30.2 1.0 C4A B:HEM1407 3.0 30.2 1.0 C4C B:HEM1407 3.1 30.6 1.0 C1C B:HEM1407 3.1 31.4 1.0 C1B B:HEM1407 3.1 30.1 1.0 C4B B:HEM1407 3.1 30.1 1.0 CHA B:HEM1407 3.4 30.8 1.0 CHD B:HEM1407 3.4 29.5 1.0 CHB B:HEM1407 3.4 29.6 1.0 CHC B:HEM1407 3.5 31.5 1.0 CB B:CYS354 3.6 33.2 1.0 CA B:CYS354 4.2 33.4 1.0 C3D B:HEM1407 4.2 32.1 1.0 C2D B:HEM1407 4.2 31.4 1.0 C2A B:HEM1407 4.2 28.8 1.0 C3A B:HEM1407 4.2 29.8 1.0 C3C B:HEM1407 4.3 32.0 1.0 C2C B:HEM1407 4.3 31.2 1.0 C2B B:HEM1407 4.3 30.1 1.0 C3B B:HEM1407 4.3 29.7 1.0 C1 B:PXI1408 4.4 36.3 1.0 N B:ILE355 4.9 31.6 1.0 CB B:ALA243 4.9 40.7 1.0 OG1 B:THR247 5.0 44.5 1.0 C B:CYS354 5.0 33.4 1.0

S.Li, H.Ouellet, D.H.Sherman, L.M.Podust. Analysis of Transient and Catalytic Desosamine Binding Pockets in Cytochrome P450 Pikc From Streptomyces Venezuelae. J.Biol.Chem. V. 284 5723 2009.
ISSN: ISSN 0021-9258
PubMed: 19124459
DOI: 10.1074/JBC.M807592200