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Atomistry » Iron » PDB 2wl9-2xdq » 2wx2 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Iron » PDB 2wl9-2xdq » 2wx2 » |
Iron in PDB 2wx2: X-Ray Structure of CYP51 From the Human Pathogen Trypanosoma Cruzi in Complex with FluconazoleEnzymatic activity of X-Ray Structure of CYP51 From the Human Pathogen Trypanosoma Cruzi in Complex with Fluconazole
All present enzymatic activity of X-Ray Structure of CYP51 From the Human Pathogen Trypanosoma Cruzi in Complex with Fluconazole:
1.14.13.70; Protein crystallography data
The structure of X-Ray Structure of CYP51 From the Human Pathogen Trypanosoma Cruzi in Complex with Fluconazole, PDB code: 2wx2
was solved by
C.-K.Chen,
S.S.F.Leung,
C.Guilbert,
M.Jacobson,
J.H.Mckerrow,
L.M.Podust,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 2wx2:
The structure of X-Ray Structure of CYP51 From the Human Pathogen Trypanosoma Cruzi in Complex with Fluconazole also contains other interesting chemical elements:
Iron Binding Sites:
The binding sites of Iron atom in the X-Ray Structure of CYP51 From the Human Pathogen Trypanosoma Cruzi in Complex with Fluconazole
(pdb code 2wx2). This binding sites where shown within
5.0 Angstroms radius around Iron atom.
In total 2 binding sites of Iron where determined in the X-Ray Structure of CYP51 From the Human Pathogen Trypanosoma Cruzi in Complex with Fluconazole, PDB code: 2wx2: Jump to Iron binding site number: 1; 2; Iron binding site 1 out of 2 in 2wx2Go back to Iron Binding Sites List in 2wx2
Iron binding site 1 out
of 2 in the X-Ray Structure of CYP51 From the Human Pathogen Trypanosoma Cruzi in Complex with Fluconazole
Mono view Stereo pair view
Iron binding site 2 out of 2 in 2wx2Go back to Iron Binding Sites List in 2wx2
Iron binding site 2 out
of 2 in the X-Ray Structure of CYP51 From the Human Pathogen Trypanosoma Cruzi in Complex with Fluconazole
Mono view Stereo pair view
Reference:
C.-K.Chen,
S.S.F.Leung,
C.Guilbert,
M.Jacobson,
J.H.Mckerrow,
L.M.Podust.
Structural Characterization of CYP51 From Trypanosoma Cruzi and Trypanosoma Brucei Bound to the Antifungal Drugs Posaconazole and Fluconazole Plos Negl Trop Dis V. 4 E651 2010.
Page generated: Sun Dec 13 14:56:08 2020
ISSN: ISSN 1935-2727 PubMed: 20386598 DOI: 10.1371/JOURNAL.PNTD.0000651 |
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