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Atomistry » Iron » PDB 2xv1-2yde » 2yde | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Iron » PDB 2xv1-2yde » 2yde » |
Iron in PDB 2yde: Factor Inhibiting Hif-1 Alpha in Complex with S-2-HydroxyglutarateEnzymatic activity of Factor Inhibiting Hif-1 Alpha in Complex with S-2-Hydroxyglutarate
All present enzymatic activity of Factor Inhibiting Hif-1 Alpha in Complex with S-2-Hydroxyglutarate:
1.14.11.16; Protein crystallography data
The structure of Factor Inhibiting Hif-1 Alpha in Complex with S-2-Hydroxyglutarate, PDB code: 2yde
was solved by
R.Chowdhury,
I.J.Clifton,
C.J.Schofield,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Iron Binding Sites:
The binding sites of Iron atom in the Factor Inhibiting Hif-1 Alpha in Complex with S-2-Hydroxyglutarate
(pdb code 2yde). This binding sites where shown within
5.0 Angstroms radius around Iron atom.
In total only one binding site of Iron was determined in the Factor Inhibiting Hif-1 Alpha in Complex with S-2-Hydroxyglutarate, PDB code: 2yde: Iron binding site 1 out of 1 in 2ydeGo back to Iron Binding Sites List in 2yde
Iron binding site 1 out
of 1 in the Factor Inhibiting Hif-1 Alpha in Complex with S-2-Hydroxyglutarate
Mono view Stereo pair view
Reference:
R.Chowdhury,
K.K.Yeoh,
Y.M.Tian,
L.Hillringhaus,
E.A.Bagg,
N.R.Rose,
I.K.Leung,
X.S.Li,
E.C.Woon,
M.Yang,
M.A.Mcdonough,
O.N.King,
I.J.Clifton,
R.J.Klose,
T.D.Claridge,
P.J.Ratcliffe,
C.J.Schofield,
A.Kawamura.
The Oncometabolite 2-Hydroxyglutarate Inhibits Histone Lysine Demethylases. Embo Rep. V. 12 463 2011.
Page generated: Sun Dec 13 14:57:48 2020
ISSN: ESSN 1469-3178 PubMed: 21460794 DOI: 10.1038/EMBOR.2011.43 |
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