Iron in PDB 2z7e: Crystal Structure of Aquifex Aeolicus Iscu with Bound [2FE- 2S] Cluster

The structure of Crystal Structure of Aquifex Aeolicus Iscu with Bound [2FE- 2S] Cluster, PDB code: 2z7e was solved by Y.Shimomura, K.Wada, Y.Takahashi, K.Fukuyama, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	47.25 / 2.30
Space group	P 21 21 2
Cell size a, b, c (Å), α, β, γ (°)	72.903, 122.136, 62.051, 90.00, 90.00, 90.00
R / Rfree (%)	22.5 / 25.2

The binding sites of Iron atom in the Crystal Structure of Aquifex Aeolicus Iscu with Bound [2FE- 2S] Cluster (pdb code 2z7e). This binding sites where shown within 5.0 Angstroms radius around Iron atom.
In total 2 binding sites of Iron where determined in the Crystal Structure of Aquifex Aeolicus Iscu with Bound [2FE- 2S] Cluster, PDB code: 2z7e:
Jump to Iron binding site number: 1; 2;

Iron binding site 1 out of 2 in the Crystal Structure of Aquifex Aeolicus Iscu with Bound [2FE- 2S] Cluster


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 1 of Crystal Structure of Aquifex Aeolicus Iscu with Bound [2FE- 2S] Cluster within 5.0Å range: probe atom residue distance (Å) B Occ B:Fe158 b:33.5 occ:1.00 FE1 B:FES158 0.0 33.5 1.0 S2 B:FES158 2.2 37.4 1.0 S1 B:FES158 2.2 31.6 1.0 SG B:CYS36 2.2 30.3 1.0 NE2 B:HIS106 2.3 40.2 1.0 CE1 B:HIS106 2.6 43.8 1.0 CB B:CYS36 3.0 28.1 1.0 FE2 B:FES158 3.0 34.5 1.0 CD2 B:HIS106 3.6 40.9 1.0 ND1 B:HIS106 3.8 44.4 1.0 CG B:HIS106 4.3 39.8 1.0 CA B:CYS36 4.4 28.6 1.0 SG B:CYS107 4.5 33.9 1.0 CB B:ALA38 4.6 34.2 1.0 N B:CYS36 4.7 27.1 1.0 CB B:ASN33 4.8 32.5 1.0 CD2 A:LEU10 4.8 36.1 1.0 CG A:GLU7 4.8 33.3 1.0 SG B:CYS63 5.0 34.3 1.0

Iron binding site 2 out of 2 in the Crystal Structure of Aquifex Aeolicus Iscu with Bound [2FE- 2S] Cluster


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 2 of Crystal Structure of Aquifex Aeolicus Iscu with Bound [2FE- 2S] Cluster within 5.0Å range: probe atom residue distance (Å) B Occ B:Fe158 b:34.5 occ:1.00 FE2 B:FES158 0.0 34.5 1.0 S1 B:FES158 2.2 31.6 1.0 S2 B:FES158 2.2 37.4 1.0 SG B:CYS107 2.3 33.9 1.0 SG B:CYS63 2.3 34.3 1.0 FE1 B:FES158 3.0 33.5 1.0 CB B:CYS63 3.3 33.5 1.0 CB B:CYS107 3.3 31.9 1.0 CA B:CYS107 3.9 32.7 1.0 O A:HOH179 4.0 43.5 1.0 NE2 B:HIS106 4.1 40.2 1.0 CB B:ALA66 4.5 36.0 1.0 N B:ALA66 4.5 39.3 1.0 CD2 B:HIS106 4.6 40.9 1.0 CE1 B:HIS106 4.6 43.8 1.0 N B:CYS107 4.6 33.6 1.0 CA B:CYS63 4.7 34.1 1.0 CD2 A:LEU10 4.7 36.1 1.0 CE2 A:PHE3 4.7 51.2 1.0 CB B:SER65 4.7 38.0 1.0 CZ A:PHE3 5.0 51.0 1.0

Y.Shimomura, K.Wada, K.Fukuyama, Y.Takahashi. The Asymmetric Trimeric Architecture of [2FE-2S] Iscu: Implications For Its Scaffolding During Iron-Sulfur Cluster Biosynthesis J.Mol.Biol. V. 383 133 2008.
ISSN: ISSN 0022-2836
PubMed: 18723024
DOI: 10.1016/J.JMB.2008.08.015