Iron in PDB 3awp: Cytochrome P450SP Alpha (CYP152B1) Mutant F288G

All present enzymatic activity of Cytochrome P450SP Alpha (CYP152B1) Mutant F288G:
1.11.2.4;

The structure of Cytochrome P450SP Alpha (CYP152B1) Mutant F288G, PDB code: 3awp was solved by T.Fujishiro, O.Shoji, S.Nagano, H.Sugimoto, Y.Shiro, Y.Watanabe, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	19.67 / 1.80
Space group	P 31 2 1
Cell size a, b, c (Å), α, β, γ (°)	94.580, 94.580, 113.449, 90.00, 90.00, 120.00
R / Rfree (%)	16 / 19

The binding sites of Iron atom in the Cytochrome P450SP Alpha (CYP152B1) Mutant F288G (pdb code 3awp). This binding sites where shown within 5.0 Angstroms radius around Iron atom.
In total only one binding site of Iron was determined in the Cytochrome P450SP Alpha (CYP152B1) Mutant F288G, PDB code: 3awp:

Iron binding site 1 out of 1 in the Cytochrome P450SP Alpha (CYP152B1) Mutant F288G


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 1 of Cytochrome P450SP Alpha (CYP152B1) Mutant F288G within 5.0Å range: probe atom residue distance (Å) B Occ A:Fe501 b:9.3 occ:1.00 FE A:HEM501 0.0 9.3 1.0 NA A:HEM501 2.0 8.0 1.0 NC A:HEM501 2.0 7.5 1.0 NB A:HEM501 2.0 8.9 1.0 ND A:HEM501 2.0 9.2 1.0 O A:HOH483 2.2 15.8 1.0 SG A:CYS361 2.3 12.3 1.0 C1A A:HEM501 3.0 7.4 1.0 C4B A:HEM501 3.0 8.7 1.0 C4C A:HEM501 3.0 8.8 1.0 C4D A:HEM501 3.0 9.4 1.0 C1C A:HEM501 3.0 7.8 1.0 C1D A:HEM501 3.1 9.1 1.0 C1B A:HEM501 3.1 9.1 1.0 C4A A:HEM501 3.1 8.5 1.0 CB A:CYS361 3.3 10.0 1.0 CHC A:HEM501 3.4 7.5 1.0 CHA A:HEM501 3.4 7.7 1.0 CHD A:HEM501 3.4 8.6 1.0 CHB A:HEM501 3.5 8.4 1.0 CA A:CYS361 4.2 9.6 1.0 C3C A:HEM501 4.3 8.7 1.0 C2C A:HEM501 4.3 8.3 1.0 C3B A:HEM501 4.3 8.8 1.0 C2B A:HEM501 4.3 8.5 1.0 C2A A:HEM501 4.3 7.4 1.0 C3A A:HEM501 4.3 8.5 1.0 C3D A:HEM501 4.3 9.2 1.0 C2D A:HEM501 4.3 8.0 1.0 NE2 A:GLN350 4.4 12.2 1.0 O A:HOH584 4.5 25.1 1.0 C2 A:PLM601 4.7 18.0 0.3 CB A:PRO242 4.7 11.1 1.0 CD A:PRO362 4.8 8.7 1.0 N A:GLY363 4.9 9.5 1.0 C A:CYS361 5.0 9.7 1.0 O A:HOH610 5.0 25.5 1.0

T.Fujishiro, O.Shoji, S.Nagano, H.Sugimoto, Y.Shiro, Y.Watanabe. Crystal Structure of H2O2-Dependent Cytochrome P450SPALPHA with Its Bound Fatty Acid Substrate: Insight Into the Regioselective Hydroxylation of Fatty Acids at the Alpha Position. J.Biol.Chem. V. 286 29941 2011.
ISSN: ISSN 0021-9258
PubMed: 21719702
DOI: 10.1074/JBC.M111.245225