Iron in PDB 3hyu: Crystal Structure of the Altitude Adapted Hemoglobin of Guinea Pig.

The structure of Crystal Structure of the Altitude Adapted Hemoglobin of Guinea Pig., PDB code: 3hyu was solved by B.Pairet, E.Jaenicke, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	19.59 / 1.67
Space group	C 2 2 21
Cell size a, b, c (Å), α, β, γ (°)	83.540, 89.950, 82.720, 90.00, 90.00, 90.00
R / Rfree (%)	17.7 / 20.3

The binding sites of Iron atom in the Crystal Structure of the Altitude Adapted Hemoglobin of Guinea Pig. (pdb code 3hyu). This binding sites where shown within 5.0 Angstroms radius around Iron atom.
In total 2 binding sites of Iron where determined in the Crystal Structure of the Altitude Adapted Hemoglobin of Guinea Pig., PDB code: 3hyu:
Jump to Iron binding site number: 1; 2;

Iron binding site 1 out of 2 in the Crystal Structure of the Altitude Adapted Hemoglobin of Guinea Pig.


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 1 of Crystal Structure of the Altitude Adapted Hemoglobin of Guinea Pig. within 5.0Å range: probe atom residue distance (Å) B Occ A:Fe142 b:8.1 occ:1.00 FE A:HEM142 0.0 8.1 1.0 NE2 A:HIS87 2.0 5.3 1.0 NC A:HEM142 2.0 8.2 1.0 NB A:HEM142 2.0 5.4 1.0 NA A:HEM142 2.1 6.2 1.0 ND A:HEM142 2.1 5.3 1.0 O A:HOH214 2.1 9.2 1.0 CE1 A:HIS87 2.9 6.0 1.0 C4C A:HEM142 3.1 7.2 1.0 C1C A:HEM142 3.1 6.2 1.0 C1D A:HEM142 3.1 8.6 1.0 C4D A:HEM142 3.1 8.7 1.0 C1B A:HEM142 3.1 6.9 1.0 CD2 A:HIS87 3.1 7.1 1.0 C4B A:HEM142 3.1 6.8 1.0 C1A A:HEM142 3.1 7.3 1.0 C4A A:HEM142 3.1 5.9 1.0 CHD A:HEM142 3.4 6.7 1.0 CHA A:HEM142 3.4 8.7 1.0 CHB A:HEM142 3.4 6.8 1.0 CHC A:HEM142 3.5 5.8 1.0 ND1 A:HIS87 4.0 6.7 1.0 CG A:HIS87 4.2 6.7 1.0 NE2 A:HIS58 4.2 8.5 1.0 C3C A:HEM142 4.3 7.3 1.0 C2C A:HEM142 4.3 6.6 1.0 C3B A:HEM142 4.3 6.8 1.0 C2B A:HEM142 4.3 5.7 1.0 C3D A:HEM142 4.3 9.6 1.0 C2D A:HEM142 4.3 9.4 1.0 C3A A:HEM142 4.3 6.5 1.0 C2A A:HEM142 4.3 7.7 1.0 CE1 A:HIS58 4.7 9.0 1.0 CG2 A:VAL62 4.8 6.7 1.0

Iron binding site 2 out of 2 in the Crystal Structure of the Altitude Adapted Hemoglobin of Guinea Pig.


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 2 of Crystal Structure of the Altitude Adapted Hemoglobin of Guinea Pig. within 5.0Å range: probe atom residue distance (Å) B Occ B:Fe147 b:11.2 occ:1.00 FE B:HEM147 0.0 11.2 1.0 NE2 B:HIS92 2.0 8.6 1.0 NC B:HEM147 2.0 8.1 1.0 NB B:HEM147 2.1 9.6 1.0 ND B:HEM147 2.1 10.1 1.0 NA B:HEM147 2.1 9.8 1.0 O B:HOH165 2.1 10.8 1.0 CE1 B:HIS92 3.0 11.9 1.0 CD2 B:HIS92 3.0 11.3 1.0 C4C B:HEM147 3.0 9.9 1.0 C1C B:HEM147 3.0 7.9 1.0 C1D B:HEM147 3.1 10.6 1.0 C4B B:HEM147 3.1 9.3 1.0 C1A B:HEM147 3.1 9.9 1.0 C1B B:HEM147 3.1 10.2 1.0 C4D B:HEM147 3.1 10.4 1.0 C4A B:HEM147 3.1 10.5 1.0 CHD B:HEM147 3.4 9.6 1.0 CHC B:HEM147 3.4 9.1 1.0 CHA B:HEM147 3.5 10.8 1.0 CHB B:HEM147 3.5 9.1 1.0 ND1 B:HIS92 4.1 12.1 1.0 CG B:HIS92 4.1 11.8 1.0 C3C B:HEM147 4.2 9.6 1.0 C2C B:HEM147 4.3 7.5 1.0 C3B B:HEM147 4.3 10.3 1.0 C2D B:HEM147 4.3 10.3 1.0 C2B B:HEM147 4.3 10.1 1.0 NE2 B:HIS63 4.3 11.7 1.0 C2A B:HEM147 4.3 10.5 1.0 C3A B:HEM147 4.3 11.2 1.0 C3D B:HEM147 4.3 11.9 1.0 CG2 B:VAL67 4.8 8.6 1.0 CE1 B:HIS63 5.0 12.5 1.0

B.Pairet, E.Jaenicke. Structure of the Altitude Adapted Hemoglobin of Guinea Pig in the R2-State. Plos One V. 5 12389 2010.
ISSN: ESSN 1932-6203
PubMed: 20811494
DOI: 10.1371/JOURNAL.PONE.0012389