Iron in PDB 3ia3: A Cis-Proline in Alpha-Hemoglobin Stabilizing Protein Directs the Structural Reorganization of Alpha-Hemoglobin

The structure of A Cis-Proline in Alpha-Hemoglobin Stabilizing Protein Directs the Structural Reorganization of Alpha-Hemoglobin, PDB code: 3ia3 was solved by L.Feng, P.D.Jeffrey, Y.Shi, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	21.25 / 3.20
Space group	P 61 2 2
Cell size a, b, c (Å), α, β, γ (°)	65.230, 65.230, 439.660, 90.00, 90.00, 120.00
R / Rfree (%)	23 / 29.3

The binding sites of Iron atom in the A Cis-Proline in Alpha-Hemoglobin Stabilizing Protein Directs the Structural Reorganization of Alpha-Hemoglobin (pdb code 3ia3). This binding sites where shown within 5.0 Angstroms radius around Iron atom.
In total 2 binding sites of Iron where determined in the A Cis-Proline in Alpha-Hemoglobin Stabilizing Protein Directs the Structural Reorganization of Alpha-Hemoglobin, PDB code: 3ia3:
Jump to Iron binding site number: 1; 2;

Iron binding site 1 out of 2 in the A Cis-Proline in Alpha-Hemoglobin Stabilizing Protein Directs the Structural Reorganization of Alpha-Hemoglobin


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 1 of A Cis-Proline in Alpha-Hemoglobin Stabilizing Protein Directs the Structural Reorganization of Alpha-Hemoglobin within 5.0Å range: probe atom residue distance (Å) B Occ B:Fe201 b:34.2 occ:1.00 FE B:HEM201 0.0 34.2 1.0 ND B:HEM201 2.0 32.4 1.0 NE2 B:HIS87 2.0 48.3 1.0 NA B:HEM201 2.0 35.2 1.0 NC B:HEM201 2.1 34.7 1.0 NB B:HEM201 2.1 39.0 1.0 NE2 B:HIS58 2.2 48.1 1.0 CE1 B:HIS87 2.9 52.4 1.0 C4D B:HEM201 3.0 34.5 1.0 C1D B:HEM201 3.0 43.4 1.0 CD2 B:HIS87 3.0 49.3 1.0 C1A B:HEM201 3.0 31.2 1.0 C4C B:HEM201 3.0 39.9 1.0 C4B B:HEM201 3.1 43.1 1.0 C4A B:HEM201 3.1 38.4 1.0 C1C B:HEM201 3.1 39.6 1.0 C1B B:HEM201 3.1 35.2 1.0 CD2 B:HIS58 3.1 41.3 1.0 CE1 B:HIS58 3.2 48.5 1.0 CHA B:HEM201 3.3 30.4 1.0 CHD B:HEM201 3.3 40.9 1.0 CHC B:HEM201 3.4 46.6 1.0 CHB B:HEM201 3.5 34.3 1.0 ND1 B:HIS87 4.1 49.9 1.0 CG B:HIS87 4.1 48.3 1.0 C3D B:HEM201 4.2 46.6 1.0 C2D B:HEM201 4.2 48.6 1.0 C2A B:HEM201 4.3 29.9 1.0 ND1 B:HIS58 4.3 41.1 1.0 CG B:HIS58 4.3 46.0 1.0 C3C B:HEM201 4.3 41.3 1.0 C3A B:HEM201 4.3 34.3 1.0 C3B B:HEM201 4.3 43.4 1.0 C2C B:HEM201 4.3 32.7 1.0 C2B B:HEM201 4.4 36.6 1.0 CG2 B:VAL62 4.9 49.5 1.0

Iron binding site 2 out of 2 in the A Cis-Proline in Alpha-Hemoglobin Stabilizing Protein Directs the Structural Reorganization of Alpha-Hemoglobin


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 2 of A Cis-Proline in Alpha-Hemoglobin Stabilizing Protein Directs the Structural Reorganization of Alpha-Hemoglobin within 5.0Å range: probe atom residue distance (Å) B Occ D:Fe201 b:33.5 occ:1.00 FE D:HEM201 0.0 33.5 1.0 ND D:HEM201 2.0 34.5 1.0 NE2 D:HIS87 2.0 33.2 1.0 NA D:HEM201 2.0 40.5 1.0 NC D:HEM201 2.1 37.8 1.0 NB D:HEM201 2.1 36.3 1.0 NE2 D:HIS58 2.2 53.5 1.0 CE1 D:HIS87 3.0 38.9 1.0 CD2 D:HIS87 3.0 35.4 1.0 C1D D:HEM201 3.0 44.6 1.0 C4D D:HEM201 3.0 36.2 1.0 C4C D:HEM201 3.0 44.0 1.0 C1A D:HEM201 3.0 41.0 1.0 C1C D:HEM201 3.1 40.8 1.0 C4A D:HEM201 3.1 49.2 1.0 C4B D:HEM201 3.1 41.0 1.0 C1B D:HEM201 3.1 36.9 1.0 CD2 D:HIS58 3.1 45.8 1.0 CE1 D:HIS58 3.2 58.2 1.0 CHD D:HEM201 3.3 45.9 1.0 CHA D:HEM201 3.4 37.6 1.0 CHC D:HEM201 3.4 47.3 1.0 CHB D:HEM201 3.5 50.0 1.0 ND1 D:HIS87 4.1 38.1 1.0 CG D:HIS87 4.1 38.7 1.0 C3D D:HEM201 4.2 43.1 1.0 C2D D:HEM201 4.2 43.0 1.0 C3C D:HEM201 4.3 47.1 1.0 C2A D:HEM201 4.3 38.2 1.0 ND1 D:HIS58 4.3 48.6 1.0 CG D:HIS58 4.3 47.8 1.0 C2C D:HEM201 4.3 40.0 1.0 C3B D:HEM201 4.3 43.8 1.0 C3A D:HEM201 4.3 43.9 1.0 C2B D:HEM201 4.3 39.3 1.0 CG2 D:VAL62 4.8 46.7 1.0

D.A.Gell, L.Feng, S.Zhou, P.D.Jeffrey, K.Bendak, A.Gow, M.J.Weiss, Y.Shi, J.P.Mackay. A Cis-Proline in Alpha-Hemoglobin Stabilizing Protein Directs the Structural Reorganization of Alpha-Hemoglobin. J.Biol.Chem. V. 284 29462 2009.
ISSN: ISSN 0021-9258
PubMed: 19706593
DOI: 10.1074/JBC.M109.027045