Iron in PDB 3lfm: Crystal Structure of the Fat Mass and Obesity Associated (Fto) Protein Reveals Basis For Its Substrate Specificity

The structure of Crystal Structure of the Fat Mass and Obesity Associated (Fto) Protein Reveals Basis For Its Substrate Specificity, PDB code: 3lfm was solved by J.Chai, Z.Han, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	20.00 / 2.50
Space group	H 3
Cell size a, b, c (Å), α, β, γ (°)	142.860, 142.860, 83.800, 90.00, 90.00, 120.00
R / Rfree (%)	23.9 / 28.5

The binding sites of Iron atom in the Crystal Structure of the Fat Mass and Obesity Associated (Fto) Protein Reveals Basis For Its Substrate Specificity (pdb code 3lfm). This binding sites where shown within 5.0 Angstroms radius around Iron atom.
In total only one binding site of Iron was determined in the Crystal Structure of the Fat Mass and Obesity Associated (Fto) Protein Reveals Basis For Its Substrate Specificity, PDB code: 3lfm:

Iron binding site 1 out of 1 in the Crystal Structure of the Fat Mass and Obesity Associated (Fto) Protein Reveals Basis For Its Substrate Specificity


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 1 of Crystal Structure of the Fat Mass and Obesity Associated (Fto) Protein Reveals Basis For Its Substrate Specificity within 5.0Å range: probe atom residue distance (Å) B Occ A:Fe507 b:89.8 occ:1.00 OD1 A:ASP233 2.1 55.0 1.0 O2' A:OGA1550 2.2 89.0 1.0 NE2 A:HIS307 2.7 45.4 1.0 C2 A:OGA1550 2.7 88.6 1.0 O2 A:OGA1550 2.7 92.0 1.0 NE2 A:HIS231 2.8 40.4 1.0 C1 A:OGA1550 3.0 91.1 1.0 CG A:ASP233 3.0 49.9 1.0 OD2 A:ASP233 3.2 52.9 1.0 CE1 A:HIS307 3.2 43.5 1.0 CE1 A:HIS231 3.5 36.3 1.0 N1 A:OGA1550 3.8 84.6 1.0 CD2 A:HIS231 3.9 39.6 1.0 CD2 A:HIS307 3.9 44.2 1.0 O1 A:OGA1550 4.0 91.2 1.0 NH2 A:ARG322 4.1 53.6 1.0 C4 A:OGA1550 4.1 80.9 1.0 CB A:ASP233 4.4 48.4 1.0 CN A:3DT506 4.4 0.6 1.0 ND1 A:HIS307 4.5 44.3 1.0 O2 A:3DT506 4.6 0.8 1.0 N3 A:3DT506 4.6 0.2 1.0 ND1 A:HIS231 4.7 38.5 1.0 C2 A:3DT506 4.7 0.4 1.0 CA A:ASP233 4.8 46.8 1.0 CG A:HIS307 4.9 43.7 1.0 CG A:HIS231 4.9 39.4 1.0 N A:ASP233 5.0 44.6 1.0

Z.Han, T.Niu, J.Chang, X.Lei, M.Zhao, Q.Wang, W.Cheng, J.Wang, Y.Feng, J.Chai. Crystal Structure of the Fto Protein Reveals Basis For Its Substrate Specificity Nature V. 464 1205 2010.
ISSN: ISSN 0028-0836
PubMed: 20376003
DOI: 10.1038/NATURE08921