Iron in PDB 3m9s: Crystal Structure of Respiratory Complex I From Thermus Thermophilus

All present enzymatic activity of Crystal Structure of Respiratory Complex I From Thermus Thermophilus:
1.6.5.3; 1.6.99.5;

The structure of Crystal Structure of Respiratory Complex I From Thermus Thermophilus, PDB code: 3m9s was solved by R.G.Efremov, R.Baradaran, L.A.Sazanov, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	30.00 / 4.50
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	96.390, 336.090, 262.240, 90.00, 100.59, 90.00
R / Rfree (%)	n/a / n/a

Pages:

>>> Page 1 <<< Page 2, Binding sites: 11 - 20; Page 3, Binding sites: 21 - 30; Page 4, Binding sites: 31 - 40; Page 5, Binding sites: 41 - 50; Page 6, Binding sites: 51 - 60; Page 7, Binding sites: 61 - 64;

Binding sites:

The binding sites of Iron atom in the Crystal Structure of Respiratory Complex I From Thermus Thermophilus (pdb code 3m9s). This binding sites where shown within 5.0 Angstroms radius around Iron atom.
In total 64 binding sites of Iron where determined in the Crystal Structure of Respiratory Complex I From Thermus Thermophilus, PDB code: 3m9s:
Jump to Iron binding site number: 1; 2; 3; 4; 5; 6; 7; 8; 9; 10;

Iron binding site 1 out of 64 in the Crystal Structure of Respiratory Complex I From Thermus Thermophilus


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 1 of Crystal Structure of Respiratory Complex I From Thermus Thermophilus within 5.0Å range: probe atom residue distance (Å) B Occ 6:Fe182 b:80.0 occ:1.00 FE1 6:SF4182 0.0 80.0 1.0 S2 6:SF4182 2.3 80.0 1.0 S3 6:SF4182 2.3 80.0 1.0 SG 6:CYS111 2.3 80.0 1.0 S4 6:SF4182 2.3 80.0 1.0 FE4 6:SF4182 2.6 80.0 1.0 FE3 6:SF4182 2.8 80.0 1.0 FE2 6:SF4182 2.8 80.0 1.0 CB 6:CYS111 3.3 80.0 1.0 CD 6:ARG83 3.5 80.0 1.0 S1 6:SF4182 3.9 80.0 1.0 N 6:CYS111 4.0 80.0 1.0 NE 6:ARG83 4.2 80.0 1.0 CA 6:CYS111 4.2 80.0 1.0 N 6:ARG83 4.4 80.0 1.0 CE2 6:PHE118 4.6 80.0 1.0 SG 6:CYS140 4.6 80.0 1.0 CG 6:ARG83 4.7 80.0 1.0 CB 6:ARG83 4.8 80.0 1.0 SG 6:CYS45 4.8 80.0 1.0 SG 6:CYS46 4.9 80.0 1.0 C 6:GLY82 5.0 80.0 1.0

Iron binding site 2 out of 64 in the Crystal Structure of Respiratory Complex I From Thermus Thermophilus


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 2 of Crystal Structure of Respiratory Complex I From Thermus Thermophilus within 5.0Å range: probe atom residue distance (Å) B Occ 6:Fe182 b:80.0 occ:1.00 FE2 6:SF4182 0.0 80.0 1.0 S1 6:SF4182 2.3 80.0 1.0 SG 6:CYS46 2.3 80.0 1.0 S3 6:SF4182 2.3 80.0 1.0 S4 6:SF4182 2.3 80.0 1.0 FE3 6:SF4182 2.6 80.0 1.0 FE1 6:SF4182 2.8 80.0 1.0 FE4 6:SF4182 2.8 80.0 1.0 CB 6:CYS46 3.4 80.0 1.0 N 6:CYS46 3.9 80.0 1.0 S2 6:SF4182 3.9 80.0 1.0 CA 6:CYS46 4.1 80.0 1.0 CB 6:PRO141 4.1 80.0 1.0 CA 6:PRO141 4.2 80.0 1.0 SG 6:CYS45 4.6 80.0 1.0 CA 6:GLY82 4.6 80.0 1.0 CA 6:CYS140 4.7 80.0 1.0 N 6:PRO141 4.7 80.0 1.0 C 6:CYS45 4.8 80.0 1.0 CB 6:CYS45 4.8 80.0 1.0 SG 6:CYS140 4.8 80.0 1.0 SG 6:CYS111 4.9 80.0 1.0 O 6:MET108 4.9 80.0 1.0 C 6:CYS140 5.0 80.0 1.0

Iron binding site 3 out of 64 in the Crystal Structure of Respiratory Complex I From Thermus Thermophilus


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 3 of Crystal Structure of Respiratory Complex I From Thermus Thermophilus within 5.0Å range: probe atom residue distance (Å) B Occ 6:Fe182 b:80.0 occ:1.00 FE3 6:SF4182 0.0 80.0 1.0 SG 6:CYS45 2.3 80.0 1.0 S1 6:SF4182 2.3 80.0 1.0 S2 6:SF4182 2.3 80.0 1.0 S4 6:SF4182 2.3 80.0 1.0 FE2 6:SF4182 2.6 80.0 1.0 FE4 6:SF4182 2.7 80.0 1.0 FE1 6:SF4182 2.8 80.0 1.0 CB 6:CYS45 3.3 80.0 1.0 S3 6:SF4182 3.8 80.0 1.0 NE 6:ARG83 3.8 80.0 1.0 NE2 4:HIS169 4.0 80.0 1.0 CA 6:CYS45 4.1 80.0 1.0 N 6:CYS45 4.1 80.0 1.0 N 6:CYS46 4.2 80.0 1.0 CD 6:ARG83 4.2 80.0 1.0 C 6:CYS45 4.5 80.0 1.0 CG 4:ARG84 4.6 80.0 1.0 SG 6:CYS46 4.6 80.0 1.0 CD2 4:HIS169 4.8 80.0 1.0 SG 6:CYS140 4.8 80.0 1.0 CE1 4:HIS169 4.8 80.0 1.0 CB 6:ALA44 4.9 80.0 1.0 SG 6:CYS111 4.9 80.0 1.0 C 6:ALA44 4.9 80.0 1.0 CZ 6:ARG83 4.9 80.0 1.0

Iron binding site 4 out of 64 in the Crystal Structure of Respiratory Complex I From Thermus Thermophilus


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 4 of Crystal Structure of Respiratory Complex I From Thermus Thermophilus within 5.0Å range: probe atom residue distance (Å) B Occ 6:Fe182 b:80.0 occ:1.00 FE4 6:SF4182 0.0 80.0 1.0 SG 6:CYS140 2.3 80.0 1.0 S3 6:SF4182 2.3 80.0 1.0 S2 6:SF4182 2.3 80.0 1.0 S1 6:SF4182 2.3 80.0 1.0 FE1 6:SF4182 2.6 80.0 1.0 FE3 6:SF4182 2.7 80.0 1.0 FE2 6:SF4182 2.8 80.0 1.0 CB 6:CYS140 3.3 80.0 1.0 CA 6:CYS140 3.5 80.0 1.0 C 6:CYS140 3.8 80.0 1.0 S4 6:SF4182 3.9 80.0 1.0 O 6:CYS140 4.2 80.0 1.0 N 6:PRO141 4.3 80.0 1.0 NE 4:ARG84 4.3 80.0 1.0 SG 6:CYS111 4.6 80.0 1.0 NH2 4:ARG84 4.6 80.0 1.0 CA 6:PRO141 4.6 80.0 1.0 CD1 9:ILE99 4.6 80.0 1.0 NE2 4:HIS169 4.6 80.0 1.0 CD2 4:HIS169 4.6 80.0 1.0 SG 6:CYS45 4.8 80.0 1.0 SG 6:CYS46 4.9 80.0 1.0 N 6:CYS140 4.9 80.0 1.0 CZ 4:ARG84 4.9 80.0 1.0 CG1 9:ILE99 5.0 80.0 1.0 O 6:GLY139 5.0 80.0 1.0

Iron binding site 5 out of 64 in the Crystal Structure of Respiratory Complex I From Thermus Thermophilus


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 5 of Crystal Structure of Respiratory Complex I From Thermus Thermophilus within 5.0Å range: probe atom residue distance (Å) B Occ 9:Fe183 b:80.0 occ:1.00 FE1 9:SF4183 0.0 80.0 1.0 S3 9:SF4183 2.3 80.0 1.0 S2 9:SF4183 2.3 80.0 1.0 S4 9:SF4183 2.3 80.0 1.0 SG 9:CYS101 2.3 80.0 1.0 FE4 9:SF4183 2.6 80.0 1.0 FE3 9:SF4183 2.7 80.0 1.0 FE2 9:SF4183 2.7 80.0 1.0 CB 9:CYS101 3.4 80.0 1.0 N 9:CYS101 3.5 80.0 1.0 S1 9:SF4183 3.8 80.0 1.0 CD 9:PRO64 3.9 80.0 1.0 CA 9:CYS101 4.0 80.0 1.0 N 9:GLY102 4.2 80.0 1.0 N 9:PHE100 4.2 80.0 1.0 C 9:PHE100 4.5 80.0 1.0 N 9:LEU103 4.5 80.0 1.0 SG 9:CYS63 4.5 80.0 1.0 CB 9:LEU103 4.5 80.0 1.0 CA 9:PHE100 4.5 80.0 1.0 CG2 9:ILE99 4.5 80.0 1.0 SG 9:CYS104 4.6 80.0 1.0 C 9:CYS101 4.6 80.0 1.0 CG 9:PRO64 4.7 80.0 1.0 N 9:ILE99 4.8 80.0 1.0 CD1 9:LEU103 4.8 80.0 1.0 SG 9:CYS98 4.8 80.0 1.0 N 9:CYS104 4.9 80.0 1.0

Iron binding site 6 out of 64 in the Crystal Structure of Respiratory Complex I From Thermus Thermophilus


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 6 of Crystal Structure of Respiratory Complex I From Thermus Thermophilus within 5.0Å range: probe atom residue distance (Å) B Occ 9:Fe183 b:80.0 occ:1.00 FE2 9:SF4183 0.0 80.0 1.0 S4 9:SF4183 2.3 80.0 1.0 SG 9:CYS98 2.3 80.0 1.0 S1 9:SF4183 2.3 80.0 1.0 S3 9:SF4183 2.3 80.0 1.0 FE1 9:SF4183 2.7 80.0 1.0 FE4 9:SF4183 2.7 80.0 1.0 FE3 9:SF4183 2.7 80.0 1.0 CB 9:CYS98 3.4 80.0 1.0 NE2 9:HIS41 3.6 80.0 1.0 N 9:PHE100 3.6 80.0 1.0 N 9:ILE99 3.7 80.0 1.0 CA 9:CYS98 3.7 80.0 1.0 S2 9:SF4183 3.9 80.0 1.0 CE1 9:HIS41 4.1 80.0 1.0 CA 9:PHE100 4.1 80.0 1.0 C 9:CYS98 4.1 80.0 1.0 N 9:CYS101 4.6 80.0 1.0 C 9:ILE99 4.7 80.0 1.0 SG 9:CYS101 4.7 80.0 1.0 CA 9:ILE99 4.7 80.0 1.0 SG 9:CYS104 4.8 80.0 1.0 SG 9:CYS63 4.8 80.0 1.0 CD2 9:HIS41 4.8 80.0 1.0 C 9:PHE100 4.9 80.0 1.0

Iron binding site 7 out of 64 in the Crystal Structure of Respiratory Complex I From Thermus Thermophilus


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 7 of Crystal Structure of Respiratory Complex I From Thermus Thermophilus within 5.0Å range: probe atom residue distance (Å) B Occ 9:Fe183 b:80.0 occ:1.00 FE3 9:SF4183 0.0 80.0 1.0 SG 9:CYS104 2.3 80.0 1.0 S4 9:SF4183 2.3 80.0 1.0 S2 9:SF4183 2.3 80.0 1.0 S1 9:SF4183 2.3 80.0 1.0 FE1 9:SF4183 2.7 80.0 1.0 FE2 9:SF4183 2.7 80.0 1.0 FE4 9:SF4183 2.8 80.0 1.0 CB 9:CYS104 3.2 80.0 1.0 NE2 9:HIS41 3.6 80.0 1.0 N 9:CYS104 3.9 80.0 1.0 S3 9:SF4183 4.0 80.0 1.0 CA 9:CYS104 4.2 80.0 1.0 CD2 9:HIS41 4.2 80.0 1.0 CD1 9:ILE68 4.4 80.0 1.0 N 9:GLY102 4.7 80.0 1.0 SG 9:CYS98 4.7 80.0 1.0 CE1 9:HIS41 4.8 80.0 1.0 N 9:LEU103 4.8 80.0 1.0 SG 9:CYS63 4.8 80.0 1.0 SG 9:CYS101 4.9 80.0 1.0

Iron binding site 8 out of 64 in the Crystal Structure of Respiratory Complex I From Thermus Thermophilus


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 8 of Crystal Structure of Respiratory Complex I From Thermus Thermophilus within 5.0Å range: probe atom residue distance (Å) B Occ 9:Fe183 b:80.0 occ:1.00 FE4 9:SF4183 0.0 80.0 1.0 SG 9:CYS63 2.3 80.0 1.0 S1 9:SF4183 2.3 80.0 1.0 S3 9:SF4183 2.3 80.0 1.0 S2 9:SF4183 2.3 80.0 1.0 FE1 9:SF4183 2.6 80.0 1.0 FE2 9:SF4183 2.7 80.0 1.0 FE3 9:SF4183 2.8 80.0 1.0 CB 9:CYS63 3.2 80.0 1.0 CA 9:CYS63 3.8 80.0 1.0 S4 9:SF4183 3.9 80.0 1.0 CD 9:PRO64 3.9 80.0 1.0 C 9:CYS63 4.5 80.0 1.0 CD1 9:ILE68 4.5 80.0 1.0 CG1 9:ILE68 4.5 80.0 1.0 CB 9:ALA67 4.5 80.0 1.0 N 9:PRO64 4.6 80.0 1.0 SG 9:CYS101 4.7 80.0 1.0 SG 9:CYS98 4.8 80.0 1.0 SG 9:CYS104 4.9 80.0 1.0 N 9:CYS63 5.0 80.0 1.0

Iron binding site 9 out of 64 in the Crystal Structure of Respiratory Complex I From Thermus Thermophilus


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 9 of Crystal Structure of Respiratory Complex I From Thermus Thermophilus within 5.0Å range: probe atom residue distance (Å) B Occ 9:Fe184 b:80.0 occ:1.00 FE1 9:SF4184 0.0 80.0 1.0 S3 9:SF4184 2.3 80.0 1.0 S4 9:SF4184 2.3 80.0 1.0 SG 9:CYS108 2.3 80.0 1.0 S2 9:SF4184 2.3 80.0 1.0 FE3 9:SF4184 2.6 80.0 1.0 FE2 9:SF4184 2.7 80.0 1.0 FE4 9:SF4184 2.8 80.0 1.0 CB 9:CYS108 3.4 80.0 1.0 CB 9:ALA112 3.6 80.0 1.0 OG1 9:THR110 3.8 80.0 1.0 CA 9:CYS108 3.9 80.0 1.0 CD 9:PRO109 3.9 80.0 1.0 S1 9:SF4184 3.9 80.0 1.0 N 9:ILE113 4.5 80.0 1.0 N 9:PRO109 4.5 80.0 1.0 CG2 9:ILE113 4.6 80.0 1.0 N 9:ALA112 4.7 80.0 1.0 C 9:CYS108 4.7 80.0 1.0 CA 9:ALA112 4.7 80.0 1.0 SG 9:CYS59 4.7 80.0 1.0 SG 9:CYS56 4.7 80.0 1.0 SG 9:CYS53 4.8 80.0 1.0 N 9:THR110 4.9 80.0 1.0 CB 9:CYS59 4.9 80.0 1.0

Iron binding site 10 out of 64 in the Crystal Structure of Respiratory Complex I From Thermus Thermophilus


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 10 of Crystal Structure of Respiratory Complex I From Thermus Thermophilus within 5.0Å range: probe atom residue distance (Å) B Occ 9:Fe184 b:80.0 occ:1.00 FE2 9:SF4184 0.0 80.0 1.0 SG 9:CYS59 2.2 80.0 1.0 S4 9:SF4184 2.3 80.0 1.0 S1 9:SF4184 2.3 80.0 1.0 S3 9:SF4184 2.3 80.0 1.0 FE3 9:SF4184 2.6 80.0 1.0 FE1 9:SF4184 2.7 80.0 1.0 FE4 9:SF4184 2.8 80.0 1.0 CB 9:CYS59 3.3 80.0 1.0 N 9:CYS59 3.9 80.0 1.0 S2 9:SF4184 3.9 80.0 1.0 OH 9:TYR91 4.1 80.0 1.0 CE1 9:TYR91 4.2 80.0 1.0 CA 9:CYS59 4.2 80.0 1.0 N 9:LEU58 4.4 80.0 1.0 CZ 9:TYR91 4.5 80.0 1.0 N 9:SER57 4.6 80.0 1.0 CG2 9:ILE113 4.6 80.0 1.0 SG 9:CYS53 4.6 80.0 1.0 SG 9:CYS56 4.7 80.0 1.0 CA 9:SER57 4.7 80.0 1.0 SG 9:CYS108 4.7 80.0 1.0 C 9:SER57 5.0 80.0 1.0 C 9:LEU58 5.0 80.0 1.0

R.G.Efremov, R.Baradaran, L.A.Sazanov. The Architecture of Respiratory Complex I Nature V. 465 441 2010.
ISSN: ISSN 0028-0836
PubMed: 20505720
DOI: 10.1038/NATURE09066