Iron »
PDB 3m38-3mma »
3me6 »
Iron in PDB 3me6: Crystal Structure of Cytochrome 2B4 in Complex with the Anti-Platelet Drug Clopidogrel
Enzymatic activity of Crystal Structure of Cytochrome 2B4 in Complex with the Anti-Platelet Drug Clopidogrel
All present enzymatic activity of Crystal Structure of Cytochrome 2B4 in Complex with the Anti-Platelet Drug Clopidogrel:
1.14.14.1;
1.14.14.1;
Protein crystallography data
The structure of Crystal Structure of Cytochrome 2B4 in Complex with the Anti-Platelet Drug Clopidogrel, PDB code: 3me6
was solved by
S.C.Gay,
A.G.Roberts,
K.Maekawa,
J.C.Talakad,
W.X.Hong,
Q.Zhang,
C.D.Stout,
J.R.Halpert,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
| Resolution Low / High (Å) | 76.75 / 3.10 |
| Space group | P 3 |
| Cell size a, b, c (Å), α, β, γ (°) | 234.490, 234.490, 57.320, 90.00, 90.00, 120.00 |
| R / Rfree (%) | 17.8 / 23.4 |
Other elements in 3me6:
The structure of Crystal Structure of Cytochrome 2B4 in Complex with the Anti-Platelet Drug Clopidogrel also contains other interesting chemical elements:
| Chlorine | (Cl) | 4 atoms |
Iron Binding Sites:
The binding sites of Iron atom in the Crystal Structure of Cytochrome 2B4 in Complex with the Anti-Platelet Drug Clopidogrel
(pdb code 3me6). This binding sites where shown within
5.0 Angstroms radius around Iron atom.
In total 4 binding sites of Iron where determined in the Crystal Structure of Cytochrome 2B4 in Complex with the Anti-Platelet Drug Clopidogrel, PDB code: 3me6:
Jump to Iron binding site number: 1; 2; 3; 4;
In total 4 binding sites of Iron where determined in the Crystal Structure of Cytochrome 2B4 in Complex with the Anti-Platelet Drug Clopidogrel, PDB code: 3me6:
Jump to Iron binding site number: 1; 2; 3; 4;
Iron binding site 1 out of 4 in 3me6
Go back to
Iron Binding Sites List in 3me6
Iron binding site 1 out
of 4 in the Crystal Structure of Cytochrome 2B4 in Complex with the Anti-Platelet Drug Clopidogrel
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Iron with other atoms in the Fe binding
site number 1 of Crystal Structure of Cytochrome 2B4 in Complex with the Anti-Platelet Drug Clopidogrel within 5.0Å range:
|
Iron binding site 2 out of 4 in 3me6
Go back to
Iron Binding Sites List in 3me6
Iron binding site 2 out
of 4 in the Crystal Structure of Cytochrome 2B4 in Complex with the Anti-Platelet Drug Clopidogrel
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Iron with other atoms in the Fe binding
site number 2 of Crystal Structure of Cytochrome 2B4 in Complex with the Anti-Platelet Drug Clopidogrel within 5.0Å range:
|
Iron binding site 3 out of 4 in 3me6
Go back to
Iron Binding Sites List in 3me6
Iron binding site 3 out
of 4 in the Crystal Structure of Cytochrome 2B4 in Complex with the Anti-Platelet Drug Clopidogrel
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Iron with other atoms in the Fe binding
site number 3 of Crystal Structure of Cytochrome 2B4 in Complex with the Anti-Platelet Drug Clopidogrel within 5.0Å range:
|
Iron binding site 4 out of 4 in 3me6
Go back to
Iron Binding Sites List in 3me6
Iron binding site 4 out
of 4 in the Crystal Structure of Cytochrome 2B4 in Complex with the Anti-Platelet Drug Clopidogrel
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Iron with other atoms in the Fe binding
site number 4 of Crystal Structure of Cytochrome 2B4 in Complex with the Anti-Platelet Drug Clopidogrel within 5.0Å range:
|
Reference:
S.C.Gay,
A.G.Roberts,
K.Maekawa,
J.C.Talakad,
W.X.Hong,
Q.Zhang,
C.D.Stout,
J.R.Halpert.
Structures of Cytochrome P450 2B4 Complexed with the Antiplatelet Drugs Ticlopidine and Clopidogrel. Biochemistry V. 49 8709 2010.
ISSN: ISSN 0006-2960
PubMed: 20815363
DOI: 10.1021/BI100914Z
Page generated: Sun Aug 4 14:46:52 2024
ISSN: ISSN 0006-2960
PubMed: 20815363
DOI: 10.1021/BI100914Z
Last articles
Zn in 9JYWZn in 9IR4
Zn in 9IR3
Zn in 9GMX
Zn in 9GMW
Zn in 9JEJ
Zn in 9ERF
Zn in 9ERE
Zn in 9EGV
Zn in 9EGW
