Iron in PDB 3o1a: Structure of Oxye (CYP165D3), A Cytochrome P450 Involved in Teicoplanin Biosynthesis

All present enzymatic activity of Structure of Oxye (CYP165D3), A Cytochrome P450 Involved in Teicoplanin Biosynthesis:
1.14.14.1;

The structure of Structure of Oxye (CYP165D3), A Cytochrome P450 Involved in Teicoplanin Biosynthesis, PDB code: 3o1a was solved by M.J.Cryle, I.Schlichting, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	49.27 / 2.50
Space group	P 31
Cell size a, b, c (Å), α, β, γ (°)	75.680, 75.680, 74.720, 90.00, 90.00, 120.00
R / Rfree (%)	22 / 27.4

The binding sites of Iron atom in the Structure of Oxye (CYP165D3), A Cytochrome P450 Involved in Teicoplanin Biosynthesis (pdb code 3o1a). This binding sites where shown within 5.0 Angstroms radius around Iron atom.
In total only one binding site of Iron was determined in the Structure of Oxye (CYP165D3), A Cytochrome P450 Involved in Teicoplanin Biosynthesis, PDB code: 3o1a:

Iron binding site 1 out of 1 in the Structure of Oxye (CYP165D3), A Cytochrome P450 Involved in Teicoplanin Biosynthesis


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 1 of Structure of Oxye (CYP165D3), A Cytochrome P450 Involved in Teicoplanin Biosynthesis within 5.0Å range: probe atom residue distance (Å) B Occ A:Fe385 b:66.0 occ:1.00 FE A:HEM385 0.0 66.0 1.0 O A:HOH391 2.0 84.1 1.0 NC A:HEM385 2.0 66.2 1.0 NB A:HEM385 2.1 65.8 1.0 NA A:HEM385 2.1 65.1 1.0 ND A:HEM385 2.1 68.0 1.0 SG A:CYS332 2.4 76.2 1.0 C4C A:HEM385 3.0 67.9 1.0 C1C A:HEM385 3.0 67.1 1.0 C4A A:HEM385 3.1 65.5 1.0 C1B A:HEM385 3.1 65.7 1.0 C4B A:HEM385 3.1 66.4 1.0 C1D A:HEM385 3.1 68.2 1.0 C1A A:HEM385 3.1 65.7 1.0 C4D A:HEM385 3.1 67.7 1.0 CB A:CYS332 3.3 75.5 1.0 CHD A:HEM385 3.4 68.3 1.0 CHB A:HEM385 3.4 65.7 1.0 CHC A:HEM385 3.4 66.8 1.0 CHA A:HEM385 3.5 66.4 1.0 CA A:CYS332 4.1 76.4 1.0 C3C A:HEM385 4.2 67.3 1.0 C2C A:HEM385 4.2 66.8 1.0 C3A A:HEM385 4.3 64.9 1.0 C3B A:HEM385 4.3 67.0 1.0 C2B A:HEM385 4.3 66.9 1.0 C2A A:HEM385 4.3 64.8 1.0 C2D A:HEM385 4.4 69.1 1.0 C3D A:HEM385 4.4 68.5 1.0 CE A:MET226 4.5 78.8 1.0 C A:CYS332 4.9 78.4 1.0

M.J.Cryle, J.Staaden, I.Schlichting. Structural Characterization of CYP165D3, A Cytochrome P450 Involved in Phenolic Coupling in Teicoplanin Biosynthesis. Arch.Biochem.Biophys. V. 507 163 2011.
ISSN: ISSN 0003-9861
PubMed: 20974107
DOI: 10.1016/J.ABB.2010.10.017