Iron in PDB 3ovq: Crystal Structure of Hrpe and D-Ribulose-5-Phospate Complex

All present enzymatic activity of Crystal Structure of Hrpe and D-Ribulose-5-Phospate Complex:
5.1.3.1;

The structure of Crystal Structure of Hrpe and D-Ribulose-5-Phospate Complex, PDB code: 3ovq was solved by W.G.Liang, S.Y.Ouyang, N.Shaw, A.Joachimiak, R.G.Zhang, Z.J.Liu, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	25.94 / 2.00
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	61.785, 43.535, 72.269, 90.00, 94.88, 90.00
R / Rfree (%)	14.7 / 19.1

The binding sites of Iron atom in the Crystal Structure of Hrpe and D-Ribulose-5-Phospate Complex (pdb code 3ovq). This binding sites where shown within 5.0 Angstroms radius around Iron atom.
In total 2 binding sites of Iron where determined in the Crystal Structure of Hrpe and D-Ribulose-5-Phospate Complex, PDB code: 3ovq:
Jump to Iron binding site number: 1; 2;

Iron binding site 1 out of 2 in the Crystal Structure of Hrpe and D-Ribulose-5-Phospate Complex


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 1 of Crystal Structure of Hrpe and D-Ribulose-5-Phospate Complex within 5.0Å range: probe atom residue distance (Å) B Occ A:Fe229 b:24.0 occ:1.00 OD1 A:ASP37 2.1 23.6 1.0 O4 A:5RP230 2.2 26.7 1.0 OD2 A:ASP175 2.2 22.5 1.0 NE2 A:HIS35 2.2 18.7 1.0 ND1 A:HIS70 2.3 20.2 1.0 O13 A:5RP230 2.3 21.3 1.0 C3 A:5RP230 3.0 31.8 1.0 CD2 A:HIS35 3.1 17.9 1.0 CE1 A:HIS70 3.1 15.8 1.0 CG A:ASP37 3.1 26.6 1.0 CG A:ASP175 3.2 27.6 1.0 C5 A:5RP230 3.2 35.3 1.0 CE1 A:HIS35 3.3 16.7 1.0 CG A:HIS70 3.3 21.0 1.0 OD2 A:ASP37 3.5 28.8 1.0 OD1 A:ASP175 3.5 27.0 1.0 CB A:HIS70 3.7 18.1 1.0 CE A:MET72 4.2 22.1 1.0 NE2 A:HIS70 4.3 23.0 1.0 CG A:HIS35 4.3 17.1 1.0 ND1 A:HIS35 4.3 19.9 1.0 C6 A:5RP230 4.4 40.3 1.0 CD2 A:HIS70 4.4 19.8 1.0 C2 A:5RP230 4.4 28.2 1.0 CB A:ASP37 4.5 24.2 1.0 CB A:ASP175 4.5 21.0 1.0 O1 A:5RP230 4.7 25.6 1.0 CG1 A:VAL195 5.0 28.7 1.0

Iron binding site 2 out of 2 in the Crystal Structure of Hrpe and D-Ribulose-5-Phospate Complex


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 2 of Crystal Structure of Hrpe and D-Ribulose-5-Phospate Complex within 5.0Å range: probe atom residue distance (Å) B Occ B:Fe229 b:24.2 occ:1.00 OD1 B:ASP37 2.1 21.2 1.0 NE2 B:HIS35 2.2 16.0 1.0 O4 B:5RP230 2.2 24.8 1.0 OD2 B:ASP175 2.3 22.2 1.0 ND1 B:HIS70 2.3 18.3 1.0 O13 B:5RP230 2.3 26.8 1.0 C3 B:5RP230 3.0 33.2 1.0 CG B:ASP37 3.1 27.2 1.0 CD2 B:HIS35 3.1 17.1 1.0 CE1 B:HIS70 3.1 18.1 1.0 CG B:ASP175 3.2 26.0 1.0 C5 B:5RP230 3.2 37.0 1.0 CE1 B:HIS35 3.3 15.0 1.0 CG B:HIS70 3.3 16.2 1.0 OD1 B:ASP175 3.5 26.1 1.0 OD2 B:ASP37 3.5 27.3 1.0 CB B:HIS70 3.7 18.7 1.0 CE B:MET72 4.2 19.6 1.0 CG B:HIS35 4.3 16.3 1.0 NE2 B:HIS70 4.3 20.8 1.0 ND1 B:HIS35 4.4 16.7 1.0 CB B:ASP37 4.4 23.3 1.0 C6 B:5RP230 4.4 43.4 1.0 CD2 B:HIS70 4.4 16.1 1.0 C2 B:5RP230 4.5 30.1 1.0 CB B:ASP175 4.5 21.4 1.0 O1 B:5RP230 4.8 32.2 1.0 CA B:ASP37 4.9 23.4 1.0 SD B:MET72 4.9 21.0 1.0

W.G.Liang, S.Y.Ouyang, N.Shaw, A.Joachimiak, R.G.Zhang, Z.J.Liu. Conversion of D-Ribulose 5-Phosphate to D-Xylulose 5-Phosphate: New Insights From Structural and Biochemical Studies on Human Rpe Faseb J. V. 25 497 2011.
ISSN: ISSN 0892-6638
PubMed: 20923965
DOI: 10.1096/FJ.10-171207