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Atomistry » Iron » PDB 3tgu-3u3e » 3tyn | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Iron » PDB 3tgu-3u3e » 3tyn » |
Iron in PDB 3tyn: Structure of Neuronal Nitric Oxide Synthase Heme Domain in Complex with 2-(((2-(((3S,4S)-4-((6-Amino-4-Methylpyridin-2-Yl)Methyl) Pyrrolidin-3-Yl)Oxy)Ethyl)Amino)Methyl)PhenolEnzymatic activity of Structure of Neuronal Nitric Oxide Synthase Heme Domain in Complex with 2-(((2-(((3S,4S)-4-((6-Amino-4-Methylpyridin-2-Yl)Methyl) Pyrrolidin-3-Yl)Oxy)Ethyl)Amino)Methyl)Phenol
All present enzymatic activity of Structure of Neuronal Nitric Oxide Synthase Heme Domain in Complex with 2-(((2-(((3S,4S)-4-((6-Amino-4-Methylpyridin-2-Yl)Methyl) Pyrrolidin-3-Yl)Oxy)Ethyl)Amino)Methyl)Phenol:
1.14.13.39; Protein crystallography data
The structure of Structure of Neuronal Nitric Oxide Synthase Heme Domain in Complex with 2-(((2-(((3S,4S)-4-((6-Amino-4-Methylpyridin-2-Yl)Methyl) Pyrrolidin-3-Yl)Oxy)Ethyl)Amino)Methyl)Phenol, PDB code: 3tyn
was solved by
H.Li,
T.L.Poulos,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 3tyn:
The structure of Structure of Neuronal Nitric Oxide Synthase Heme Domain in Complex with 2-(((2-(((3S,4S)-4-((6-Amino-4-Methylpyridin-2-Yl)Methyl) Pyrrolidin-3-Yl)Oxy)Ethyl)Amino)Methyl)Phenol also contains other interesting chemical elements:
Iron Binding Sites:
The binding sites of Iron atom in the Structure of Neuronal Nitric Oxide Synthase Heme Domain in Complex with 2-(((2-(((3S,4S)-4-((6-Amino-4-Methylpyridin-2-Yl)Methyl) Pyrrolidin-3-Yl)Oxy)Ethyl)Amino)Methyl)Phenol
(pdb code 3tyn). This binding sites where shown within
5.0 Angstroms radius around Iron atom.
In total 2 binding sites of Iron where determined in the Structure of Neuronal Nitric Oxide Synthase Heme Domain in Complex with 2-(((2-(((3S,4S)-4-((6-Amino-4-Methylpyridin-2-Yl)Methyl) Pyrrolidin-3-Yl)Oxy)Ethyl)Amino)Methyl)Phenol, PDB code: 3tyn: Jump to Iron binding site number: 1; 2; Iron binding site 1 out of 2 in 3tynGo back to Iron Binding Sites List in 3tyn
Iron binding site 1 out
of 2 in the Structure of Neuronal Nitric Oxide Synthase Heme Domain in Complex with 2-(((2-(((3S,4S)-4-((6-Amino-4-Methylpyridin-2-Yl)Methyl) Pyrrolidin-3-Yl)Oxy)Ethyl)Amino)Methyl)Phenol
Mono view Stereo pair view
Iron binding site 2 out of 2 in 3tynGo back to Iron Binding Sites List in 3tyn
Iron binding site 2 out
of 2 in the Structure of Neuronal Nitric Oxide Synthase Heme Domain in Complex with 2-(((2-(((3S,4S)-4-((6-Amino-4-Methylpyridin-2-Yl)Methyl) Pyrrolidin-3-Yl)Oxy)Ethyl)Amino)Methyl)Phenol
Mono view Stereo pair view
Reference:
K.J.Labby,
F.Xue,
J.M.Kraus,
H.Ji,
J.Mataka,
H.Li,
P.Martasek,
L.J.Roman,
T.L.Poulos,
R.B.Silverman.
Intramolecular Hydrogen Bonding: A Potential Strategy For More Bioavailable Inhibitors of Neuronal Nitric Oxide Synthase. Bioorg.Med.Chem. V. 20 2435 2012.
Page generated: Sun Aug 4 20:38:50 2024
ISSN: ISSN 0968-0896 PubMed: 22370337 DOI: 10.1016/J.BMC.2012.01.037 |
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