Iron in PDB 3wrl: Crystal Structure of P450CAM

All present enzymatic activity of Crystal Structure of P450CAM:
1.14.15.1;

The structure of Crystal Structure of P450CAM, PDB code: 3wrl was solved by A.Kishimoto, K.Takagi, A.Amano, K.Sakurai, T.Mizushima, H.Shimada, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	38.66 / 1.65
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	66.885, 62.835, 95.731, 90.00, 90.83, 90.00
R / Rfree (%)	18.5 / 22.7

The structure of Crystal Structure of P450CAM also contains other interesting chemical elements:

Potassium

(K)

2 atoms

The binding sites of Iron atom in the Crystal Structure of P450CAM (pdb code 3wrl). This binding sites where shown within 5.0 Angstroms radius around Iron atom.
In total 2 binding sites of Iron where determined in the Crystal Structure of P450CAM, PDB code: 3wrl:
Jump to Iron binding site number: 1; 2;

Iron binding site 1 out of 2 in the Crystal Structure of P450CAM


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 1 of Crystal Structure of P450CAM within 5.0Å range: probe atom residue distance (Å) B Occ A:Fe501 b:9.5 occ:1.00 FE A:HEM501 0.0 9.5 1.0 NA A:HEM501 2.1 8.3 1.0 NB A:HEM501 2.1 8.9 1.0 NC A:HEM501 2.1 9.2 1.0 ND A:HEM501 2.1 8.2 1.0 SG A:CYS357 2.4 9.8 1.0 C1C A:HEM501 3.1 8.2 1.0 C4D A:HEM501 3.1 6.9 1.0 C4C A:HEM501 3.1 10.6 1.0 C1B A:HEM501 3.1 8.0 1.0 C1A A:HEM501 3.1 7.4 1.0 C1D A:HEM501 3.1 9.7 1.0 C4A A:HEM501 3.1 7.0 1.0 C4B A:HEM501 3.1 8.0 1.0 CB A:CYS357 3.3 10.4 1.0 CHC A:HEM501 3.4 9.5 1.0 CHA A:HEM501 3.4 7.6 1.0 CHD A:HEM501 3.5 10.2 1.0 CHB A:HEM501 3.5 7.5 1.0 C5 A:CAM503 4.1 14.3 1.0 CA A:CYS357 4.1 9.2 1.0 C2C A:HEM501 4.3 10.3 1.0 C3B A:HEM501 4.3 7.5 1.0 C3C A:HEM501 4.3 9.6 1.0 C2A A:HEM501 4.3 7.1 1.0 C3A A:HEM501 4.3 7.3 1.0 C2B A:HEM501 4.3 6.9 1.0 C2D A:HEM501 4.3 10.6 1.0 C3D A:HEM501 4.3 10.5 1.0 N A:GLY359 4.5 10.4 1.0 N A:LEU358 4.6 9.4 1.0 C4 A:CAM503 4.7 12.9 1.0 C A:CYS357 4.7 10.1 1.0 CA A:GLY359 4.9 11.2 1.0 C9 A:CAM503 4.9 13.7 1.0

Iron binding site 2 out of 2 in the Crystal Structure of P450CAM


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 2 of Crystal Structure of P450CAM within 5.0Å range: probe atom residue distance (Å) B Occ E:Fe501 b:13.9 occ:1.00 FE E:HEM501 0.0 13.9 1.0 ND E:HEM501 2.0 10.9 1.0 NB E:HEM501 2.0 13.9 1.0 NA E:HEM501 2.1 13.3 1.0 NC E:HEM501 2.1 11.1 1.0 SG E:CYS357 2.4 14.2 1.0 C4D E:HEM501 3.0 14.0 1.0 C1D E:HEM501 3.0 11.6 1.0 C4B E:HEM501 3.0 15.9 1.0 C1C E:HEM501 3.1 12.5 1.0 C1B E:HEM501 3.1 10.8 1.0 C1A E:HEM501 3.1 12.6 1.0 C4A E:HEM501 3.1 13.7 1.0 C4C E:HEM501 3.1 12.4 1.0 CHA E:HEM501 3.4 12.8 1.0 CB E:CYS357 3.4 12.8 1.0 CHC E:HEM501 3.4 15.2 1.0 CHD E:HEM501 3.5 12.2 1.0 CHB E:HEM501 3.5 12.1 1.0 C5 E:CAM503 4.0 20.2 1.0 CA E:CYS357 4.1 13.6 1.0 C3B E:HEM501 4.3 14.0 1.0 C3D E:HEM501 4.3 13.3 1.0 C2D E:HEM501 4.3 14.3 1.0 C2C E:HEM501 4.3 10.5 1.0 C3C E:HEM501 4.3 10.7 1.0 C2A E:HEM501 4.3 13.6 1.0 C2B E:HEM501 4.3 11.3 1.0 C3A E:HEM501 4.3 14.0 1.0 N E:GLY359 4.5 14.3 1.0 C4 E:CAM503 4.6 19.0 1.0 N E:LEU358 4.7 15.6 1.0 C E:CYS357 4.8 15.5 1.0 C9 E:CAM503 4.8 16.0 1.0 CA E:GLY359 4.9 13.3 1.0

A.Kishimoto, K.Takagi, A.Amano, K.Sakurai, Y.Katayama, R.Aminaka, M.Ito, T.Mizushima, H.Shimada. Structure of P450CAM Intermedite To Be Published.