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Atomistry » Iron » PDB 4egn-4f2n » 4enh » |
Iron in PDB 4enh: Crystal Structure of Human Cytochrome P450 CYP46A1 with Fluvoxamine BoundEnzymatic activity of Crystal Structure of Human Cytochrome P450 CYP46A1 with Fluvoxamine Bound
All present enzymatic activity of Crystal Structure of Human Cytochrome P450 CYP46A1 with Fluvoxamine Bound:
1.14.13.98; Protein crystallography data
The structure of Crystal Structure of Human Cytochrome P450 CYP46A1 with Fluvoxamine Bound, PDB code: 4enh
was solved by
C.D.Stout,
N.Mast,
I.A.Pikuleva,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 4enh:
The structure of Crystal Structure of Human Cytochrome P450 CYP46A1 with Fluvoxamine Bound also contains other interesting chemical elements:
Iron Binding Sites:
The binding sites of Iron atom in the Crystal Structure of Human Cytochrome P450 CYP46A1 with Fluvoxamine Bound
(pdb code 4enh). This binding sites where shown within
5.0 Angstroms radius around Iron atom.
In total only one binding site of Iron was determined in the Crystal Structure of Human Cytochrome P450 CYP46A1 with Fluvoxamine Bound, PDB code: 4enh: Iron binding site 1 out of 1 in 4enhGo back to Iron Binding Sites List in 4enh
Iron binding site 1 out
of 1 in the Crystal Structure of Human Cytochrome P450 CYP46A1 with Fluvoxamine Bound
Mono view Stereo pair view
Reference:
N.Mast,
M.Linger,
M.Clark,
J.Wiseman,
C.D.Stout,
I.A.Pikuleva.
In Silico and Intuitive Predictions of CYP46A1 Inhibition By Marketed Drugs with Subsequent Enzyme Crystallization in Complex with Fluvoxamine. Mol.Pharmacol. V. 82 824 2012.
Page generated: Sun Dec 13 15:32:56 2020
ISSN: ISSN 0026-895X PubMed: 22859721 DOI: 10.1124/MOL.112.080424 |
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