Iron in PDB 4hlt: Crystal Structure of Ferric E32V Pirin

All present enzymatic activity of Crystal Structure of Ferric E32V Pirin:
1.13.11.24;

The structure of Crystal Structure of Ferric E32V Pirin, PDB code: 4hlt was solved by F.Liu, I.Rehmani, S.Esaki, R.Fu, L.Chen, V.Serrano, A.Liu, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	31.84 / 1.70
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	42.414, 66.635, 107.330, 90.00, 90.00, 90.00
R / Rfree (%)	18.4 / 23.4

The binding sites of Iron atom in the Crystal Structure of Ferric E32V Pirin (pdb code 4hlt). This binding sites where shown within 5.0 Angstroms radius around Iron atom.
In total only one binding site of Iron was determined in the Crystal Structure of Ferric E32V Pirin, PDB code: 4hlt:

Iron binding site 1 out of 1 in the Crystal Structure of Ferric E32V Pirin


Mono view


Stereo pair view

A full contact list of Iron with other atoms in the Fe binding site number 1 of Crystal Structure of Ferric E32V Pirin within 5.0Å range: probe atom residue distance (Å) B Occ A:Fe1001 b:15.4 occ:1.00 NE2 A:HIS101 2.1 14.5 1.0 NE2 A:HIS58 2.1 16.2 1.0 NE2 A:HIS56 2.1 13.7 1.0 OE2 A:GLU103 2.2 21.1 1.0 CE1 A:HIS101 3.0 16.1 1.0 CE1 A:HIS58 3.1 16.1 1.0 CE1 A:HIS56 3.1 15.4 1.0 CD2 A:HIS56 3.1 14.0 1.0 CD2 A:HIS58 3.2 15.6 1.0 CD2 A:HIS101 3.2 15.2 1.0 CD A:GLU103 3.2 21.5 1.0 OE1 A:GLU103 3.6 22.2 1.0 O A:HOH1203 4.1 34.7 1.0 ND1 A:HIS101 4.1 15.2 1.0 ND1 A:HIS58 4.2 18.4 1.0 ND1 A:HIS56 4.2 16.6 1.0 CG A:HIS101 4.3 14.4 1.0 CG A:HIS56 4.3 15.0 1.0 CG A:HIS58 4.3 15.6 1.0 NE2 A:GLN115 4.3 18.0 1.0 CG A:GLU103 4.4 19.7 1.0 OG1 A:THR63 4.9 21.6 1.0 CG2 A:THR63 5.0 15.1 1.0 OE1 A:GLN115 5.0 33.5 1.0

F.Liu, I.Rehmani, S.Esaki, R.Fu, L.Chen, V.De Serrano, A.Liu. Pirin Is An Iron-Dependent Redox Regulator of Nf-Kappa B. Proc.Natl.Acad.Sci.Usa V. 110 9722 2013.
ISSN: ISSN 0027-8424
PubMed: 23716661
DOI: 10.1073/PNAS.1221743110